-
1
-
-
0027367546
-
Amino acid polymorphisms of insulin receptor substrate-1 in non-insulin dependent diabetes mellitus
-
Almind K, Bjørbæk C, Verstergaard H, Hansen T, Echwald S, Pedersen O: Amino acid polymorphisms of insulin receptor substrate-1 in non-insulin dependent diabetes mellitus. Lancet 242: 828-832, 1993
-
(1993)
Lancet
, vol.242
, pp. 828-832
-
-
Almind, K.1
Bjørbæk, C.2
Verstergaard, H.3
Hansen, T.4
Echwald, S.5
Pedersen, O.6
-
2
-
-
0029905523
-
Phenotypic characterization of the Trp 64 Arg polymorphism in the beta3-adrenergic receptor gene in normal weight and obese subjects
-
Arner P: Phenotypic characterization of the Trp 64 Arg polymorphism in the beta3-adrenergic receptor gene in normal weight and obese subjects. Diabetologia 39: 857-860, 1996
-
(1996)
Diabetologia
, vol.39
, pp. 857-860
-
-
Arner, P.1
-
3
-
-
0028940934
-
An amino acid substitution in the human intestinal fatty acid binding protein is associated with the increased fatty acid binding, increased fat oxidation and insulin resistance
-
Baier LJ, Sacchettini JC, Knowler WC, Eads J, Paolisso G, Tatarinm PA, Mochizuki H, Bennett PH, Bogardus C, Prochazka M: An amino acid substitution in the human intestinal fatty acid binding protein is associated with the increased fatty acid binding, increased fat oxidation and insulin resistance. J Clin Invest 95: 1281-1287, 1995
-
(1995)
J Clin Invest
, vol.95
, pp. 1281-1287
-
-
Baier, L.J.1
Sacchettini, J.C.2
Knowler, W.C.3
Eads, J.4
Paolisso, G.5
Tatarinm, P.A.6
Mochizuki, H.7
Bennett, P.H.8
Bogardus, C.9
Prochazka, M.10
-
4
-
-
13344259300
-
Evidence that the db/db gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice
-
Chen H, Charlat O, Tartaglia LA, Woolf EA, Weng X, Ellis SJ, Lakey ND, Culpepper J, Moore KJ, Breibart RE, Duyk GM, Tepper RI, Morgenstern JP: Evidence that the db/db gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell 84: 491-495, 1996
-
(1996)
Cell
, vol.84
, pp. 491-495
-
-
Chen, H.1
Charlat, O.2
Tartaglia, L.A.3
Woolf, E.A.4
Weng, X.5
Ellis, S.J.6
Lakey, N.D.7
Culpepper, J.8
Moore, K.J.9
Breibart, R.E.10
Duyk, G.M.11
Tepper, R.I.12
Morgenstern, J.P.13
-
5
-
-
0030028959
-
Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (Leptin) receptor
-
Chua SC, Jr, Chung WK, Wu-Peng XS, Xhang Y, Liu SM, Tartaglia LA, Leibel RL. Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (Leptin) receptor. Science 271: 994-996, 1996
-
(1996)
Science
, vol.271
, pp. 994-996
-
-
Chua Jr., S.C.1
Chung, W.K.2
Wu-Peng, X.S.3
Xhang, Y.4
Liu, S.M.5
Tartaglia, L.A.6
Leibel, R.L.7
-
6
-
-
15144353456
-
Exonic and intronic sequence variation in the human leptin receptor gene (LE PR)
-
Chung WK, Power-Kehoe L, Chua M, Chu F, Aronne L, Huma Z, Sothern M, Udall JN, Kahle B, Leibel RL. Exonic and intronic sequence variation in the human leptin receptor gene (LE PR). Diabetes 46: 1509-1511, 1997
-
(1997)
Diabetes
, vol.46
, pp. 1509-1511
-
-
Chung, W.K.1
Power-Kehoe, L.2
Chua, M.3
Chu, F.4
Aronne, L.5
Huma, Z.6
Sothern, M.7
Udall, J.N.8
Kahle, B.9
Leibel, R.L.10
-
7
-
-
0029775612
-
Insulin sensitivity index, acute insulin response, and glucose effectiveness in population-based sample of 380 young healthy Caucasians
-
Clausen JO, Borch-Johnsen K, Ibsen H, Bergman RN, Hougaard P, Winther K, Pedersen O: Insulin sensitivity index, acute insulin response, and glucose effectiveness in population-based sample of 380 young healthy Caucasians. J Clin Invest 98: 1195-1209, 1996
-
(1996)
J Clin Invest
, vol.98
, pp. 1195-1209
-
-
Clausen, J.O.1
Borch-Johnsen, K.2
Ibsen, H.3
Bergman, R.N.4
Hougaard, P.5
Winther, K.6
Pedersen, O.7
-
8
-
-
0029118510
-
Insulin resistance: Interactions between obesity and a common variant of the insulin receptor substrate-1
-
Clausen JO, Hansen T, Bjørbæk C, Echwald SM, Urhammer SA, Rasmussen S, Andersen CB, Hansen L, Almind K, Winther K, Haraldsdottir J, Borch-Johnsen K, Pedersen P: Insulin resistance: interactions between obesity and a common variant of the insulin receptor substrate-1. Lancet 346: 397-402, 1995
-
(1995)
Lancet
, vol.346
, pp. 397-402
-
-
Clausen, J.O.1
Hansen, T.2
Bjørbæk, C.3
Echwald, S.M.4
Urhammer, S.A.5
Rasmussen, S.6
Andersen, C.B.7
Hansen, L.8
Almind, K.9
Winther, K.10
Haraldsdottir, J.11
Borch-Johnsen, K.12
Pedersen, P.13
-
9
-
-
85038190584
-
3-adrenergic receptor gene in normal weight and obese subjects
-
3-adrenergic receptor gene in normal weight and obese subjects. Diabetologia 39: 857-860, 1996
-
(1996)
Diabetologia
, vol.39
, pp. 857-860
-
-
Clement, K.1
Vaisse, C.2
Manning, B.S.J.3
Basdevant, A.4
Guy-Grand, B.5
Ruiz, J.6
Silver, K.D.7
Shuldiner, A.R.8
Froguel, P.9
Strosberg, D.10
-
10
-
-
0029885220
-
The hypothalamic leptin receptor in humans: Identification of incidental sequence polymorphisms and absence of the db/db mouse and fa/fa rat mutations
-
Considine RV, Considine EL, Williams CJ, Hyde TM, Caro JF: The hypothalamic leptin receptor in humans: identification of incidental sequence polymorphisms and absence of the db/db mouse and fa/fa rat mutations. Diabetes 45: 992-994, 1996
-
(1996)
Diabetes
, vol.45
, pp. 992-994
-
-
Considine, R.V.1
Considine, E.L.2
Williams, C.J.3
Hyde, T.M.4
Caro, J.F.5
-
11
-
-
0029020677
-
Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity
-
Considine RV, Considine EL, Williams CJ, Nyce MR, Magosin SA, Bauer TL, Rosato EL, Colberg J, Caro JF: Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity. J Clin Invest 95: 2986-2988, 1995
-
(1995)
J Clin Invest
, vol.95
, pp. 2986-2988
-
-
Considine, R.V.1
Considine, E.L.2
Williams, C.J.3
Nyce, M.R.4
Magosin, S.A.5
Bauer, T.L.6
Rosato, E.L.7
Colberg, J.8
Caro, J.F.9
-
12
-
-
0030724591
-
Pathogenesis of Type II diabetes: Metabolic and molecular implications for identifying diabetes genes
-
De Fronzo RA: Pathogenesis of Type II diabetes: metabolic and molecular implications for identifying diabetes genes. Diabetes Reviews 3: 177-269, 1997
-
(1997)
Diabetes Reviews
, vol.3
, pp. 177-269
-
-
De Fronzo, R.A.1
-
13
-
-
0030935153
-
Identification of two novel missense mutations in the human OB gene
-
Echwald SM, Rasmussen SB, Sørensen TIA, Andersen T, Tybjærg-Hansen A, Clausen JO, Hansen L, Hansen T, Pedersen O: Identification of two novel missense mutations in the human OB gene. Int J Obes 21: 321-326, 1997
-
(1997)
Int J Obes
, vol.21
, pp. 321-326
-
-
Echwald, S.M.1
Rasmussen, S.B.2
Sørensen, T.I.A.3
Andersen, T.4
Tybjærg-Hansen, A.5
Clausen, J.O.6
Hansen, L.7
Hansen, T.8
Pedersen, O.9
-
14
-
-
17344387584
-
Amino-acid variants in the human leptin receptor: Lack of association to juvenile-onset obesity
-
Echwald SM, Sørensen TIA, Tybjærg-Hansen A, Andersen T, Chung WK, Leibel RL, Pedersen O: Amino-acid variants in the human leptin receptor: lack of association to juvenile-onset obesity. Biochem Biophys Res Commun 233: 248-252, 1997
-
(1997)
Biochem Biophys Res Commun
, vol.233
, pp. 248-252
-
-
Echwald, S.M.1
Sørensen, T.I.A.2
Tybjærg-Hansen, A.3
Andersen, T.4
Chung, W.K.5
Leibel, R.L.6
Pedersen, O.7
-
15
-
-
9044228020
-
3-adrenergic receptor with NIDDM and body weight gain
-
3-adrenergic receptor with NIDDM and body weight gain. Diabetologia 39: 349-352, 1996
-
(1996)
Diabetologia
, vol.39
, pp. 349-352
-
-
Fujisawa, T.1
Ikegami, H.2
Yamato, E.3
Takekawa, K.4
Nakagawa, Y.5
Hamada, Y.6
Oga, T.7
Yeda, H.8
Shintani, M.9
Fukuda, M.10
Ogihara, T.11
-
16
-
-
0030927064
-
Leptin receptor gene variation and obesity: Lack of association in a white British male population
-
Gotoda T, Manning BS, Goldstone AP, Imrie H, Evans AL, Strosberg AD, McKeigue PM, Scott J, Aitman AJ: Leptin receptor gene variation and obesity: lack of association in a white British male population. Hum Mol Genet 6: 869-876, 1997
-
(1997)
Hum Mol Genet
, vol.6
, pp. 869-876
-
-
Gotoda, T.1
Manning, B.S.2
Goldstone, A.P.3
Imrie, H.4
Evans, A.L.5
Strosberg, A.D.6
McKeigue, P.M.7
Scott, J.8
Aitman, A.J.9
-
17
-
-
0027422281
-
Insulin receptor substrate 1 (IRS-1) gene polymorphisms in French NIDDM families
-
Hager J, Zouli H, Velho G, Froguel P: Insulin receptor substrate 1 (IRS-1) gene polymorphisms in French NIDDM families. Lancet 342: 1430, 1993
-
(1993)
Lancet
, vol.342
, pp. 1430
-
-
Hager, J.1
Zouli, H.2
Velho, G.3
Froguel, P.4
-
18
-
-
0029126604
-
A widespread amino acid polymorphism at codon 905 of the glycogen-associated regulatory subunit of protein phosphatase-1 is associated with insulin resistance and hypersecretion of insulin
-
Hansen L, Hansen T, Vestergaard H, Bjørbæk C, Echwald SM, Clausen JO, Chen YH, Chen MX, Cohen PTW, Pedersen O: A widespread amino acid polymorphism at codon 905 of the glycogen-associated regulatory subunit of protein phosphatase-1 is associated with insulin resistance and hypersecretion of insulin. Hum Mol Genet 4: 1313-1320, 1995
-
(1995)
Hum Mol Genet
, vol.4
, pp. 1313-1320
-
-
Hansen, L.1
Hansen, T.2
Vestergaard, H.3
Bjørbæk, C.4
Echwald, S.M.5
Clausen, J.O.6
Chen, Y.H.7
Chen, M.X.8
Ptw, C.9
Pedersen, O.10
-
19
-
-
0031046812
-
Identification of a common amino acid polymorphism in the p85a regulatory subunit of phosphatidylinositol 3-kinase
-
Hansen T, Andersen CB, Echwald SM, Urhammer SA, Clausen JO, Vestergaard H, Owens D, Hansen l, Pedersen O: Identification of a common amino acid polymorphism in the p85a regulatory subunit of phosphatidylinositol 3-kinase. Diabetes 46: 494-501, 1997
-
(1997)
Diabetes
, vol.46
, pp. 494-501
-
-
Hansen, T.1
Andersen, C.B.2
Echwald, S.M.3
Urhammer, S.A.4
Clausen, J.O.5
Vestergaard, H.6
Owens, D.7
Hansen, L.8
Pedersen, O.9
-
20
-
-
0028912848
-
Insulin receptor substrate-1 gene mutations in NIDDM: Implications for the study of polygenic disease
-
Hitman GA, Hawrami K, McCarthy MI, Viswanathan M, Snehalatha C, Ramachandran A, Tuomilehto J, Wolf E, Nissinen A, Pedersen O: Insulin receptor substrate-1 gene mutations in NIDDM: implications for the study of polygenic disease. Diabetologia 38: 481-486, 1995
-
(1995)
Diabetologia
, vol.38
, pp. 481-486
-
-
Hitman, G.A.1
Hawrami, K.2
McCarthy, M.I.3
Viswanathan, M.4
Snehalatha, C.5
Ramachandran, A.6
Tuomilehto, J.7
Wolf, E.8
Nissinen, A.9
Pedersen, O.10
-
21
-
-
0028557255
-
Variant sequences of insulin receptor substrate 1 in patients with non-insulin-dependent diabetes mellitus
-
Imai Y, Fusco A, Suzuki Y, Lesniak MA, Alfonso RD, Sesti G, Bertoli A, Lauro R, Accili D, Taylor S: Variant sequences of insulin receptor substrate 1 in patients with non-insulin-dependent diabetes mellitus. J Clin Endocrinol Metab 79: 1655-1658, 1994
-
(1994)
J Clin Endocrinol Metab
, vol.79
, pp. 1655-1658
-
-
Imai, Y.1
Fusco, A.2
Suzuki, Y.3
Lesniak, M.A.4
Alfonso, R.D.5
Sesti, G.6
Bertoli, A.7
Lauro, R.8
Accili, D.9
Taylor, S.10
-
22
-
-
0028970525
-
3-adrenergic receptor gene is associated with obesity and hyperinsulinemia in Japanese subjects
-
3-adrenergic receptor gene is associated with obesity and hyperinsulinemia in Japanese subjects. Biochem Biophys Res Commun 215: 555-560, 1995
-
(1995)
Biochem Biophys Res Commun
, vol.215
, pp. 555-560
-
-
Kadowaki, H.1
Yasuda, K.2
Iwamoto, K.3
Otabe, S.4
Shimokawa, K.5
Walston, J.6
Yoshinaga, H.7
Kosaka, K.8
Yamada, N.9
-
23
-
-
0027994029
-
Insulin receptor substrate-1 variants in non-insulin-dependent diabetes
-
Laakso M, Malkki M, Kekalainen P, Kuusisto J, Deeb SS: Insulin receptor substrate-1 variants in non-insulin-dependent diabetes. J Clin Invest 94: 1141-1146, 1994
-
(1994)
J Clin Invest
, vol.94
, pp. 1141-1146
-
-
Laakso, M.1
Malkki, M.2
Kekalainen, P.3
Kuusisto, J.4
Deeb, S.S.5
-
24
-
-
9844266242
-
Human leptin receptor gene in obese Japanese subjects: Evidence against either obesity causing mutations or association of sequence variants with obesity
-
Matsuoka N, Ogawa Y, Hosoda K, Matsuda J, Masuzaki H, Miyakawa T, Azuma N, Natsui K, Nishimura H, Yoshimasa Y, Nishi S, Thompson DB, Nakao K: Human leptin receptor gene in obese Japanese subjects: evidence against either obesity causing mutations or association of sequence variants with obesity. Diabetologia 40: 1204-1210, 1997
-
(1997)
Diabetologia
, vol.40
, pp. 1204-1210
-
-
Matsuoka, N.1
Ogawa, Y.2
Hosoda, K.3
Matsuda, J.4
Masuzaki, H.5
Miyakawa, T.6
Azuma, N.7
Natsui, K.8
Nishimura, H.9
Yoshimasa, Y.10
Nishi, S.11
Thompson, D.B.12
Nakao, K.13
-
25
-
-
0030878110
-
Congenital leptin deficiency is associated with severe early-onset obesity in humans
-
Montague CT, Faroogi IS, Whitehead JP, Soos MA, Rau H, Wareham NJ, Sewter CP, Digby JE, Mohammed SN, Hurst JA, Cheetham CH, Earley AR, Barnett AH, Prins JB, O'Rahilly S: Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature 387: 903-908, 1997
-
(1997)
Nature
, vol.387
, pp. 903-908
-
-
Montague, C.T.1
Faroogi, I.S.2
Whitehead, J.P.3
Soos, M.A.4
Rau, H.5
Wareham, N.J.6
Sewter, C.P.7
Digby, J.E.8
Mohammed, S.N.9
Hurst, J.A.10
Cheetham, C.H.11
Earley, A.R.12
Barnett, A.H.13
Prins, J.B.14
O'Rahilly, S.15
-
26
-
-
0027468540
-
Linkage of chromosomal markers at 4q with a putative gene determining maximal insulin action in Pima Indians
-
Prochazka M, Lillioja S, Tait J, Knowler WC, Mott DM, Spraul M, Bennett PH, Bogardus C: Linkage of chromosomal markers at 4q with a putative gene determining maximal insulin action in Pima Indians. Diabetes 42: 541-519, 1993
-
(1993)
Diabetes
, vol.42
, pp. 541-1519
-
-
Prochazka, M.1
Lillioja, S.2
Tait, J.3
Knowler, W.C.4
Mott, D.M.5
Spraul, M.6
Bennett, P.H.7
Bogardus, C.8
-
28
-
-
0028058980
-
Molecular scanning of the glycogen synthase and insulin receptor substrate 1 genes in Japanese subjects with non-insulin-dependent diabetes mellitus
-
Shimokawa K, Kadowaki H, Sakura H, Otabe S, Hagura R, Kosaka K, Yazaki Y, Akanuma Y, Kadowaki T: Molecular scanning of the glycogen synthase and insulin receptor substrate 1 genes in Japanese subjects with non-insulin-dependent diabetes mellitus. Biochim Biophys Res Commun 202: 463-469, 1994
-
(1994)
Biochim Biophys Res Commun
, vol.202
, pp. 463-469
-
-
Shimokawa, K.1
Kadowaki, H.2
Sakura, H.3
Otabe, S.4
Hagura, R.5
Kosaka, K.6
Yazaki, Y.7
Akanuma, Y.8
Kadowaki, T.9
-
29
-
-
0030000562
-
Codon 972 polymorphism in the insulin receptor substrate-1 gene, obesity and risk of non-insulin-dependent diabetes mellitus
-
Sigal RJ, Doria A, Warren JH, Krolewski AS: Codon 972 polymorphism in the insulin receptor substrate-1 gene, obesity and risk of non-insulin-dependent diabetes mellitus. J Clin Endocrinol Metab 81: 1657-1659, 1996
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 1657-1659
-
-
Sigal, R.J.1
Doria, A.2
Warren, J.H.3
Krolewski, A.S.4
-
31
-
-
9244256729
-
Molecular scanning of the IRS-1 gene in Japanese patients with non-insulin-dependent diabetes mellitus: Identification of five novel mutations in IRS-1 gene
-
Ura S, Araki E, Kishikawa H, Shirstani T, Todaka M, Isami S, Shiimoda S, Yoshimura R, Matsuda K, Motoyoshi S, Muyamura N, Kahn CR, Shichiri M: Molecular scanning of the IRS-1 gene in Japanese patients with non-insulin-dependent diabetes mellitus: identification of five novel mutations in IRS-1 gene. Diabetologia 39: 600-608, 1996
-
(1996)
Diabetologia
, vol.39
, pp. 600-608
-
-
Ura, S.1
Araki, E.2
Kishikawa, H.3
Shirstani, T.4
Todaka, M.5
Isami, S.6
Shiimoda, S.7
Yoshimura, R.8
Matsuda, K.9
Motoyoshi, S.10
Muyamura, N.11
Kahn, C.R.12
Shichiri, M.13
-
33
-
-
9844232617
-
Mutational analysis of the coding region of the uncoupling protein 2 gene in obese NIDDM patients: Impact of a common amino acid polymorphism on juvenile and maturity onset forms of obesity and insulin resistance
-
Urhammer SA, Dalgaard LT, Sørensen TIA, Møller AM, Andersen T, Tybjærg-Hansen A, Hansen T, Clausen JO, Vestergaard H, Pedersen O: Mutational analysis of the coding region of the uncoupling protein 2 gene in obese NIDDM patients: impact of a common amino acid polymorphism on juvenile and maturity onset forms of obesity and insulin resistance. Diabetologia 40: 1227-1230, 1997
-
(1997)
Diabetologia
, vol.40
, pp. 1227-1230
-
-
Urhammer, S.A.1
Dalgaard, L.T.2
Sørensen, T.I.A.3
Møller, A.M.4
Andersen, T.5
Tybjærg-Hansen, A.6
Hansen, T.7
Clausen, J.O.8
Vestergaard, H.9
Pedersen, O.10
-
34
-
-
0030844233
-
Studies of genetic variability of the uncoupling protein 1 gene in Caucasian subjects with juvenile onset obesity
-
Urhammer SA, Friedberg M, Sørensen TIA, Echwald SM, Andersen T, Tybjærg-Hansen A, Hansen T, Clausen JO, Vestergaard H, Pedersen O: Studies of genetic variability of the uncoupling protein 1 gene in Caucasian subjects with juvenile onset obesity. J Clin Endocrinol Metab 82: 4069-4074, 1997
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 4069-4074
-
-
Urhammer, S.A.1
Friedberg, M.2
Sørensen, T.I.A.3
Echwald, S.M.4
Andersen, T.5
Tybjærg-Hansen, A.6
Hansen, T.7
Clausen, J.O.8
Vestergaard, H.9
Pedersen, O.10
-
35
-
-
0029084088
-
3-adrenergic-receptor gene
-
3-adrenergic-receptor gene. N Engl J Med 333: 343-347, 1995
-
(1995)
N Engl J Med
, vol.333
, pp. 343-347
-
-
Walston, J.1
Silver, K.2
Bogardus, C.3
Knowler, W.C.4
Celi, F.S.5
Austin, S.6
Manning, B.7
Strosberg, D.8
Stern, M.9
Raben, N.10
Sorkin, J.D.11
Roth, J.12
Shuldiner, A.R.13
-
37
-
-
0029857775
-
3-adrenergic-receptor mutations in insulin resistance and obesity respectively with no evidence for glycogen synthase mutations. UK Prospective Diabetes Study
-
3-adrenergic-receptor mutations in insulin resistance and obesity respectively with no evidence for glycogen synthase mutations. UK Prospective Diabetes Study. Diabetologia 39(12): 1505-1511, 1996
-
(1996)
Diabetologia
, vol.39
, Issue.12
, pp. 1505-1511
-
-
Zhang, Y.1
Wat, N.2
Stratton, I.M.3
Warren-Perry, M.G.4
Orho, M.5
Groop, L.6
Turner, R.C.7
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