Cytokine-mediated increases in fetal hemoglobin are associated with globin gene histone modification and transcription factor reprogramming

Blood

Volumn 114, Issue 11, 2009, Pages 2299-2306

  Sripichai, Orapan ^a   Kiefer, Christine M ^a   Bhanu, Natarajan V ^a   Tanno, Toshihiko ^a   Noh, Seung Jae ^a   Goh, Sung Ho ^a   Russell, J Eric ^b   Rognerud, Cheryl L ^c   Ou, Ching Nan ^c   Oneal, Patricia A ^a   Meier, Emily R ^a   Gantt, Nicole M ^a   Byrnes, Colleen ^a   Lee, Y Terry ^a   Dean, Ann ^a   Miller, Jeffery L ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; EARLY GROWTH RESPONSE FACTOR 1; GAMMA GLOBIN; GLOBIN; HEMOGLOBIN F; HISTONE; INHIBITOR OF DIFFERENTIATION 2; MESSENGER RNA; NUCLEAR PROTEIN; NUCLEAR TRANSCRIPTION FACTOR; PROTEIN DERIVATIVE; RNA POLYMERASE II; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MAFF; TRANSCRIPTION FACTOR SOX6; TRANSCRIPTOME; UNCLASSIFIED DRUG; CD34 ANTIGEN;

ARTICLE; CD34 SELECTION; CELL CULTURE; CHROMATIN IMMUNOPRECIPITATION; COMPARATIVE STUDY; CONTROLLED STUDY; CULTURE TECHNIQUE; EGR1 GENE; EMBRYO; ERYTHROID CELL; ERYTHROPOIESIS; FETUS; GENE; GENE EXPRESSION PROFILING; GLOBIN GENE; HHEX GENE; HUMAN; HUMAN CELL; ID2 GENE; MAFF GENE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; SIGNAL TRANSDUCTION; SOX6 GENE; TRANSCRIPTION INITIATION; ADULT; BIOSYNTHESIS; CYTOLOGY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HEMOGLOBINOPATHY; METABOLISM; PROTEIN PROCESSING;

ADULT; ANTIGENS, CD34; CELLS, CULTURED; CYTOKINES; ERYTHROID CELLS; FETAL HEMOGLOBIN; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HEMOGLOBINOPATHIES; HISTONES; HUMANS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA POLYMERASE II; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 70349569073     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2009-05-219386     Document Type: Article

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