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Volumn 114, Issue 8, 2009, Pages 1596-1606

Reintroduction of CEBPA in MN1-overexpressing hematopoietic cells prevents their hyperproliferation and restores myeloid differentiation

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN ALPHA; CD34 ANTIGEN; COLECALCIFEROL; CCAAT ENHANCER BINDING PROTEIN; CEBPA PROTEIN, HUMAN; MN1 PROTEIN, HUMAN; RETINOIC ACID; TUMOR SUPPRESSOR PROTEIN;

EID: 70349561437     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2009-02-205443     Document Type: Article
Times cited : (26)

References (37)
  • 1
    • 0037071391 scopus 로고    scopus 로고
    • Hematopoietic cytokines, transcription factors and lineage commitment
    • Zhu J, Emerson SG. Hematopoietic cytokines, transcription factors and lineage commitment. Oncogene. 2002;21:3295-3313.
    • (2002) Oncogene , vol.21 , pp. 3295-3313
    • Zhu, J.1    Emerson, S.G.2
  • 2
    • 12844280533 scopus 로고    scopus 로고
    • Transcriptional regulation in myelopoiesis: Hematopoietic fate choice, myeloid differentiation, and leukemogenesis
    • DOI 10.1016/j.exphem.2004.08.015, PII S0301472X04003601
    • Rosmarin AG, Yang Z, Resendes KK. Transcriptional regulation in myelopoiesis: hematopoietic fate choice, myeloid differentiation, and leukemogenesis. Exp Hematol. 2005;33:131-143. (Pubitemid 40164893)
    • (2005) Experimental Hematology , vol.33 , Issue.2 , pp. 131-143
    • Rosmarin, A.G.1    Yang, Z.2    Resendes, K.K.3
  • 3
    • 33846622099 scopus 로고    scopus 로고
    • Transcription factors in myeloid development: Balancing differentiation with transformation
    • DOI 10.1038/nri2024, PII NRI2024
    • Rosenbauer F, Tenen DG. Transcription factors in myeloid development: balancing differentiation with transformation. Nat Rev Immunol. 2007;7:105-117. (Pubitemid 46174858)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.2 , pp. 105-117
    • Rosenbauer, F.1    Tenen, D.G.2
  • 4
    • 0025730106 scopus 로고
    • A t(4;22) in a meningioma points to the localization of a putative tumor-suppressor gene
    • Lekanne Deprez RH, Groen NA, van Biezen NA, et al. A t(4;22) in a meningioma points to the localization of a putative tumor-suppressor gene. Am J Hum Genet. 1991;48:783-790.
    • (1991) Am J Hum Genet , vol.48 , pp. 783-790
    • Lekanne Deprez, R.H.1    Groen, N.A.2    Van Biezen, N.A.3
  • 5
    • 0029026395 scopus 로고
    • Cloning and characterization of MN1, a gene from chromosome 22q11, which is disrupted by a balanced translocation in a meningioma
    • Lekanne Deprez RH, Riegman PH, Groen NA, et al. Cloning and characterization of MN1, a gene from chromosome 22q11, which is disrupted by a balanced translocation in a meningioma. Oncogene. 1995;10:1521-1528.
    • (1995) Oncogene , vol.10 , pp. 1521-1528
    • Lekanne Deprez, R.H.1    Riegman, P.H.2    Groen, N.A.3
  • 6
    • 0029061177 scopus 로고
    • Translocation (12;22)(p13;q11) in myeloproliferative disorders results in fusion of the ETS-like TEL gene on 12p13 to the MN1 gene on 22q11
    • Buijs A, Sherr S, van Baal S, et al. Translocation (12;22)(p13;q11) in myeloproliferative disorders results in fusion of the ETS-like TEL gene on 12p13 to the MN1 gene on 22q11. Oncogene. 1995;10:1511-1519.
    • (1995) Oncogene , vol.10 , pp. 1511-1519
    • Buijs, A.1    Sherr, S.2    Van Baal, S.3
  • 9
    • 34447642168 scopus 로고    scopus 로고
    • MN1 overexpression is an important step in the development of inv(16) AML
    • Carella C, Bonten J, Sirma S, et al. MN1 overexpression is an important step in the development of inv(16) AML. Leukemia. 2007;21:1679-1690.
    • (2007) Leukemia , vol.21 , pp. 1679-1690
    • Carella, C.1    Bonten, J.2    Sirma, S.3
  • 10
    • 28844442337 scopus 로고    scopus 로고
    • Conditional MN1-TEL knock-in mice develop acute myeloid leukemia in conjunction with overexpression of HOXA9
    • Kawagoe H, Grosveld GC. Conditional MN1-TEL knock-in mice develop acute myeloid leukemia in conjunction with overexpression of HOXA9. Blood. 2005;106:4269-4277.
    • (2005) Blood , vol.106 , pp. 4269-4277
    • Kawagoe, H.1    Grosveld, G.C.2
  • 12
    • 10344230611 scopus 로고    scopus 로고
    • Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha
    • Zhang P, Iwasaki-Arai J, Iwasaki H, et al. Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha. Immunity. 2004;21:853-863.
    • (2004) Immunity , vol.21 , pp. 853-863
    • Zhang, P.1    Iwasaki-Arai, J.2    Iwasaki, H.3
  • 13
    • 28344438648 scopus 로고    scopus 로고
    • A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis
    • Fazi F, Rosa A, Fatica A, et al. A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis. Cell. 2005;123:819-831.
    • (2005) Cell , vol.123 , pp. 819-831
    • Fazi, F.1    Rosa, A.2    Fatica, A.3
  • 14
    • 0030024112 scopus 로고    scopus 로고
    • CCAAT enhancer-binding protein (C/EBP) and AML1 (CBF alpha2) synergistically activate the macrophage colony-stimulating factor receptor promoter
    • Zhang DE, Hetherington CJ, Meyers S, et al. CCAAT enhancer-binding protein (C/EBP) and AML1 (CBF alpha2) synergistically activate the macrophage colony-stimulating factor receptor promoter. Mol Cell Biol. 1996;16:1231-1240.
    • (1996) Mol Cell Biol , vol.16 , pp. 1231-1240
    • Zhang, D.E.1    Hetherington, C.J.2    Meyers, S.3
  • 15
    • 4444233646 scopus 로고    scopus 로고
    • C/EBPα deficiency results in hyperproliferation of hematopoietic progenitor cells and disrupts macrophage development in vitro and in vivo
    • DOI 10.1182/blood-2003-11-3963
    • Heath V, Suh HC, Holman M, et al. C/EBPalpha deficiency results in hyperproliferation of hematopoietic progenitor cells and disrupts macrophage development in vitro and in vivo. Blood. 2004;104:1639-1647. (Pubitemid 39202269)
    • (2004) Blood , vol.104 , Issue.6 , pp. 1639-1647
    • Heath, V.1    Suh, H.C.2    Holman, M.3    Renn, K.4    Gooya, J.M.5    Parkin, S.6    Klarmann, K.D.7    Ortiz, M.8    Johnson, P.9    Keller, J.10
  • 16
    • 0037443154 scopus 로고    scopus 로고
    • + cells
    • DOI 10.1182/blood-2002-05-1546
    • Cammenga J, Mulloy JC, Berguido FJ, MacGrogan D, Viale A, Nimer SD. Induction of C/EBPalpha activity alters gene expression and differentiation of human CD34+ cells. Blood. 2003;101:2206-2214. (Pubitemid 36302059)
    • (2003) Blood , vol.101 , Issue.6 , pp. 2206-2214
    • Cammenga, J.1    Mulloy, J.C.2    Berguido, F.J.3    MacGrogan, D.4    Viale, A.5    Nimer, S.D.6
  • 17
    • 34548012182 scopus 로고    scopus 로고
    • + stem/progenitor cells impairs self-renewal and partially restores myelopoiesis
    • DOI 10.1182/blood-2006-10-052175
    • Schepers H, Wierenga AT, van Gosliga D, Eggen BJ, Vellenga E, Schuringa JJ. Reintroduction of C/EBPalpha in leukemic CD34+ stem/progenitor cells impairs self-renewal and partially restores myelopoiesis. Blood. 2007;110:1317-1325. (Pubitemid 47281431)
    • (2007) Blood , vol.110 , Issue.4 , pp. 1317-1325
    • Schepers, H.1    Wierenga, A.T.J.2    Van Gosliga, D.3    Eggen, B.J.L.4    Vellenga, E.5    Schuringa, J.J.6
  • 18
    • 4444254797 scopus 로고    scopus 로고
    • The leukemic fusion gene AML1-MDS1-EVI1 suppresses CEBPA in acute myeloid leukemia by activation of Calreticulin
    • Helbling D, Mueller BU, Timchenko NA, et al. The leukemic fusion gene AML1-MDS1-EVI1 suppresses CEBPA in acute myeloid leukemia by activation of Calreticulin. Proc Natl Acad Sci U S A. 2004;101:13312-13317.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 13312-13317
    • Helbling, D.1    Mueller, B.U.2    Timchenko, N.A.3
  • 23
    • 33846862464 scopus 로고    scopus 로고
    • Down-regulation of RXRα expression is essential for neutrophil development from granulocyte/monocyte progenitors
    • DOI 10.1182/blood-2006-04-020552
    • Taschner S, Koesters C, Platzer B, et al. Downregulation of RXRalpha expression is essential for neutrophil development from granulocyte/monocyte progenitors. Blood. 2007;109:971-979. (Pubitemid 46220641)
    • (2007) Blood , vol.109 , Issue.3 , pp. 971-979
    • Taschner, S.1    Koesters, C.2    Platzer, B.3    Jorgl, A.4    Ellmeier, W.5    Benesch, T.6    Strobl, H.7
  • 24
    • 70449477261 scopus 로고    scopus 로고
    • Accessed June 12, 2009
    • NCBI, GEO, Gene Expression Ommibus, http://www.nbci.nlm.nih.gov/sites/ entrez?db=gds. Accessed June 12, 2009.
    • GEO, Gene Expression Ommibus
  • 26
    • 33747177840 scopus 로고    scopus 로고
    • C/EBPalpha directs monocytic commitment of primary myeloid progenitors
    • Wang D, D'Costa J, Civin CI, Friedman AD. C/EBPalpha directs monocytic commitment of primary myeloid progenitors. Blood. 2006;108:1223-1229.
    • (2006) Blood , vol.108 , pp. 1223-1229
    • Wang, D.1    D'Costa, J.2    Civin, C.I.3    Friedman, A.D.4
  • 27
    • 31544446032 scopus 로고    scopus 로고
    • The ETS factor TEL2 is a hematopoietic oncoprotein
    • DOI 10.1182/blood-2005-03-1196
    • Carella C, Potter M, Bonten J, Rehg JE, Neale G, Grosveld GC. The ETS factor TEL2 is a hematopoietic oncoprotein. Blood. 2006;107:1124-1132. (Pubitemid 43156314)
    • (2006) Blood , vol.107 , Issue.3 , pp. 1124-1132
    • Carella, C.1    Potter, M.2    Bonten, J.3    Rehg, J.E.4    Neale, G.5    Grosveld, G.C.6
  • 29
    • 33746861562 scopus 로고    scopus 로고
    • C/EBPalpha: A tumour suppressor in multiple tissues?
    • Schuster MB, Porse BT. C/EBPalpha: a tumour suppressor in multiple tissues? Biochim Biophys Acta. 2006;1766:88-103.
    • (2006) Biochim Biophys Acta , vol.1766 , pp. 88-103
    • Schuster, M.B.1    Porse, B.T.2
  • 30
    • 24344468192 scopus 로고    scopus 로고
    • 3-regulated transcription factor MN1 stimulates vitamin D receptor-mediated transcription and inhibits osteoblastic cell proliferation
    • DOI 10.1210/me.2005-0081
    • Sutton AL, Zhang X, Ellison TI, Macdonald PN. The 1,25(OH)2D3-regulated transcription factor MN1 stimulates vitamin D receptor-mediated transcription and inhibits osteoblastic cell proliferation. Mol Endocrinol. 2005;19:2234-2244. (Pubitemid 41252819)
    • (2005) Molecular Endocrinology , vol.19 , Issue.9 , pp. 2234-2244
    • Sutton, A.L.M.1    Zhang, X.2    Ellison, T.I.3    MacDonald, P.N.4
  • 34
    • 66849099334 scopus 로고    scopus 로고
    • Investigation of C/EBPalpha function in human (versus murine) myelopoiesis provides novel insight into the impact of CEBPA mutations in acute myelogenous leukemia (AML)
    • Niebuhr B, Iwanski GB, Schwieger M, Roscher S, Stocking C, Cammenga J. Investigation of C/EBPalpha function in human (versus murine) myelopoiesis provides novel insight into the impact of CEBPA mutations in acute myelogenous leukemia (AML). Leukemia. 2009;23:978-983.
    • (2009) Leukemia , vol.23 , pp. 978-983
    • Niebuhr, B.1    Iwanski, G.B.2    Schwieger, M.3    Roscher, S.4    Stocking, C.5    Cammenga, J.6
  • 35
    • 0034624828 scopus 로고    scopus 로고
    • A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
    • DOI 10.1038/35004599
    • Akashi K, Traver D, Miyamoto T, Weissman IL. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature. 2000;404:193-197. (Pubitemid 30154488)
    • (2000) Nature , vol.404 , Issue.6774 , pp. 193-197
    • Akashi, K.1    Traver, D.2    Miyamoto, T.3    Weissman, I.L.4
  • 37
    • 42549103716 scopus 로고    scopus 로고
    • C/EBP alpha:AP-1 leucine zipper heterodimers bind novel DNA elements, activate the PU.1 promoter and direct monocyte lineage commitment more potently than C/EBP alpha homodimers or AP-1
    • Cai DH, Wang D, Keefer J, Yeamans C, Hensley K, Friedman AD. C/EBP alpha:AP-1 leucine zipper heterodimers bind novel DNA elements, activate the PU.1 promoter and direct monocyte lineage commitment more potently than C/EBP alpha homodimers or AP-1. Oncogene. 2008;27:2772-2779.
    • (2008) Oncogene , vol.27 , pp. 2772-2779
    • Cai, D.H.1    Wang, D.2    Keefer, J.3    Yeamans, C.4    Hensley, K.5    Friedman, A.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.