Formononetin promotes early fracture healing through stimulating angiogenesis by up-regulating VEGFR-2/Flk-1 in a rat fracture model

International Immunopharmacology

Volumn 9, Issue 12, 2009, Pages 1357-1365

  Huh, Jeong Eun ^a   Kwon, Na Hyun ^b   Baek, Young Hyun ^b   Lee, Jae Dong ^a   Choi, Do Young ^a   Jingushi, Seiya ^c   Kim, Kang il ^b   Park, Dong Suk ^b  

^a Kyung Hee University   (South Korea)

^b Kyung Hee University College of Medicine   (South Korea)

^c KYUSHU ROSAI HOSPITAL   (Japan)

Author keywords

Bone healing; Formononetin; Osteogenesis; VEGF; VEGF receptor

Indexed keywords

ALKALINE PHOSPHATASE; COLLAGEN TYPE 1; FORMONONETIN; OSTEOCALCIN; OSTEOPONTIN; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALLUS; CARTILAGINOUS TISSUE; CELL DIFFERENTIATION; CHONDROGENESIS; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG MECHANISM; ENCHONDRAL OSSIFICATION; FEMUR FRACTURE; FRACTURE HEALING; GENE EXPRESSION; MALE; MESENCHYMAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION;

ANIMALS; ASTRAGALUS MEMBRANACEUS; BONY CALLUS; CELL DIFFERENTIATION; CHONDROGENESIS; COLLAGEN TYPE I; DISEASE MODELS, ANIMAL; FEMUR; FRACTURES, BONE; ISOFLAVONES; MALE; MESENCHYMAL STEM CELLS; NEOVASCULARIZATION, PHYSIOLOGIC; OSTEOCALCIN; OSTEOPONTIN; PHYTOESTROGENS; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; VASCULAR ENDOTHELIAL GROWTH FACTOR A; WOUND HEALING;

EID: 70349553828     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2009.08.003     Document Type: Article

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