Quantitative measurement of the splice variants 120 and 164 of the angiogenic peptide vascular endothelial growth factor in the time flow of fracture healing: A study in the rat

Cell and Tissue Research

Volumn 309, Issue 3, 2002, Pages 387-392

  Pufe, Thomas ^a   Wildemann, Britt ^b   Petersen, Wolf ^a   Mentlein, Rolf ^a   Raschke, Michael ^b   Schmidmaier, Gerhard ^b  

^a UNIVERSITY OF KIEL   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Angiogenesis; Callus; Rat (Sprague Dawley); Tibia fracture

Indexed keywords

ANGIOGENIC FACTOR; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; CALLUS; CAPILLARY; CARTILAGE CELL; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FRACTURE HEALING; IMMUNOHISTOCHEMISTRY; MOLECULAR BIOLOGY; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; TIME;

ALTERNATIVE SPLICING; ANIMALS; BONY CALLUS; CHONDROCYTES; ENDOTHELIAL GROWTH FACTORS; FEMALE; FRACTURES, BONE; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOKINES; ORGAN SPECIFICITY; OSTEOBLASTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; VARIATION (GENETICS); VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS; WOUND HEALING;

ANIMALIA;

EID: 0036037305     PISSN: 0302766X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00441-002-0605-0     Document Type: Article

References (24)

1. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
2. Synergistic induction of endothelial tissue factor by tumor necrosis factor and vascular endothelial growth factor: Functional analysis of the tumor necrosis factor receptors
3. Reverse transcription-polymerase chain reaction products of alternatively spliced mRNAs form heteroduplexes and heteroduplex complexes
4. Molecular and biological properties of vascular endothelial growth factor
5. Sp1 recognition sites in the proximal promoter of the human vascular endothelial growth factor gene are essential for platelet-derived growth factor-induced gene expression
6. Role of the Flt-1receptor tyrosine kinase in regulating the assembly of vascular endothelium
7. The biology of fracture healing. An overview for clinicians, part I
8. VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation
9. Acceleration of fracture healing in nonhuman primates by fibroblast growth factor-2
10. Somatostatin inhibits the production of vascular endothelial growth factor in human glioma cells
11. p42/p44 MAP kinase module plays a key role in the transcriptional regulation of the vascular endothelial growth factor gene in fibroblasts
12. Spatial and temporal gene expression in chondrogenesis during fracture healing and the effects of basic fibroblast growth factor
13. Vascular endothelial growth factor and its receptors
14. The splice variants VEGF121 and VEGF165 of the angiogenic peptide vascular endothelial cell growth factor are expressed in the synovia of patients with rheumatoid arthritis
15. The splice variants VEGF121 and VEGF189 of the angiogenic peptide vascular endothelial growth factor are expressed in osteoarthritic cartilage
16. Induction of vascular endothelial growth factor by tumor necrosis factor alpha in human glioma cells. Possible roles of SP-1
17. Local application of growth factors (insulin-like growth factor-1 and transforming growth factor-beta1) from a biodegradable poly(D, L-lactide) coating of osteosynthetic implants accelerates fracture healing in rats
18. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
19. Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
20. Basic fibroblast growth factor upregulates the expression of vascular endothelial growth factor in vascular smooth muscle cells. Synergistic action with hypoxia
21. Hypoxia regulates VEGF expression and cellular proliferation by osteoblasts in vitro
22. Expression of various growth factors for cell proliferation and cytodifferentiation during fracture repair of bone