-
1
-
-
33747100570
-
Pharmacology of current and promising nucleosides for the treatment of human immunodeficiency viruses
-
Schinazi, R.F.; Hernandez-Santiago, B.I.; Hurwitz, S.J. Pharmacology of current and promising nucleosides for the treatment of human immunodeficiency viruses. Antivir. Res. 2006, 71, 322-334.
-
(2006)
Antivir. Res.
, vol.71
, pp. 322-334
-
-
Schinazi, R.F.1
Hernandez-Santiago, B.I.2
Hurwitz, S.J.3
-
2
-
-
28844487356
-
Inhibition of human immunodeficiency virus type 1 reverse transcriptase, RNase H, and integrase activities by hydroxytropolones
-
Didierjean, J.; Isel, C.; Querré, F.; Mouscadet, J.F.; Aubertin, A.M.; Valnot, J.Y.; Piettre, S.R.; Marquet, R. Inhibition of human immunodeficiency virus type 1 reverse transcriptase, RNase H, and integrase activities by hydroxytropolones. Antimicrob. Agents Chemother. 2005, 49, 4884-4894.
-
(2005)
Antimicrob. Agents Chemother.
, vol.49
, pp. 4884-4894
-
-
Didierjean, J.1
Isel, C.2
Querré, F.3
Mouscadet, J.F.4
Aubertin, A.M.5
Valnot, J.Y.6
Piettre, S.R.7
Marquet, R.8
-
3
-
-
30144438891
-
Update on HAART in HIV
-
Yeni, P. Update on HAART in HIV. J. Hepatol. 2006, 44, S100-S103.
-
(2006)
J. Hepatol.
, vol.44
-
-
Yeni, P.1
-
4
-
-
61449084539
-
Synthesis and anti-HIV integrase evaluation of 4-oxo-4H-quinolizine-3- carboxylic acid derivatives
-
Xu, Y.S.; Zeng, C.C.; Jiao, Z.G.; Hu, L.M.; Zhong, R.G. Design, synthesis and anti-HIV integrase evaluation of 4-oxo-4H-quinolizine-3-carboxylic acid derivatives. Molecules 2009, 14, 868-883.
-
(2009)
Molecules
, vol.14
, pp. 868-883
-
-
Xu, Y.S.1
Zeng, C.C.2
Jiao, Z.G.3
Hu, L.M.4
Design, G.Z.R.5
-
5
-
-
64349086788
-
O. Novel indazole non-nucleoside reverse transcriptase inhibitors using molecular hybridization based on crystallographic overlay
-
Jones, L.H.; Allan, G.; Barba, O.; Burt, C.; Corbau, R.; Dupont, T.; Knochel, T.; Irving, S.; Middleton, D.S.; Mowbray, C.E.; Perros, M.; Ringrose, H.; Swain, N.A.; Webster, R. Westby, M. Phillips, O. Novel indazole non-nucleoside reverse transcriptase inhibitors using molecular hybridization based on crystallographic overlay. J. Med. Chem. 2009, 52, 1219-1223.
-
(2009)
J. Med. Chem.
, vol.52
, pp. 1219-1223
-
-
Jones, L.H.1
Allan, G.2
Barba, O.3
Burt, C.4
Corbau, R.5
Dupont, T.6
Knochel, T.7
Irving, S.8
Middleton, D.S.9
Mowbray, C.E.10
Perros, M.11
Ringrose, H.12
Swain, N.A.13
Westby, W.R.14
Phillips, M.15
-
6
-
-
34548388846
-
Synthesis of novel derivatives of 4-amino-3-(2-furyl)-5-mercapto-1,2,4- triazole as potential HIV-1 NNRTIs
-
Wu, J.; Liu, X.; Cheng, X.; Cao, Y.; Wang, D.; Li, Z.; Xu, W.; Pannecouque, C.; Witvrouw, M.; Clercq, E.D. Synthesis of novel derivatives of 4-amino-3-(2-furyl)-5-mercapto-1,2,4-triazole as potential HIV-1 NNRTIs. Molecules 2007, 12, 2003-2016.
-
(2007)
Molecules
, vol.12
, pp. 2003-2016
-
-
Wu, J.1
Liu, X.2
Cheng, X.3
Cao, Y.4
Wang, D.5
Li, Z.6
Xu, W.7
Pannecouque, C.8
Witvrouw, M.9
Clercq, E.D.10
-
7
-
-
33847618875
-
Discovery of novel benzimidazolones as potent non-nucleoside reverse transcriptase inhibitors active against wild-type and mutant HIV-1 strains
-
Barreca, M.L.; Rao, A.; Luca, L.D.; Iraci, N.; Monforte, A.M.; Maga, G.; Clercq, E.D.; Pannecouque, C.; Balzarini, J.; Chimirri, A. Discovery of novel benzimidazolones as potent non-nucleoside reverse transcriptase inhibitors active against wild-type and mutant HIV-1 strains. Bioorg. Med. Chem. Lett. 2007, 17, 1956-1960.
-
(2007)
Bioorg. Med. Chem. Lett.
, vol.17
, pp. 1956-1960
-
-
Barreca, M.L.1
Rao, A.2
Luca, L.D.3
Iraci, N.4
Monforte, A.M.5
Maga, G.6
Clercq, E.D.7
Pannecouque, C.8
Balzarini, J.9
Chimirri, A.10
-
8
-
-
59649115687
-
Investigation on the role of the tetrazole in the binding of thiotetrazolylacetanilides with HIV-1 wild type and K103N/Y181C double mutant reverse transcriptases
-
Gagnon, A.; Landry, S.; Coulombe, R.; Jakalian, A.; Guse, I.; Thavonekham, B.; Bonnear, P.R.; Yoakim, C.; Simoneau, B. Investigation on the role of the tetrazole in the binding of thiotetrazolylacetanilides with HIV-1 wild type and K103N/Y181C double mutant reverse transcriptases. Bioorg. Med. Chem. Lett. 2009, 19, 1199-1205.
-
(2009)
Bioorg. Med. Chem. Lett.
, vol.19
, pp. 1199-1205
-
-
Gagnon, A.1
Landry, S.2
Coulombe, R.3
Jakalian, A.4
Guse, I.5
Thavonekham, B.6
Bonnear, P.R.7
Yoakim, C.8
Simoneau, B.9
-
9
-
-
58149083480
-
Synthesis, and biological evaluation of a series of 2- hydroxyisoquinoline-1,3(2H,4H)-diones as dual inhibitors of human immunodeficiency virus type 1 integrase and the reverse transcriptase RNase H domain
-
Billamboz, M.; Bailly, F.; Barreca, M.L.; Luca, L.D.; Mouscadet, J.; Calmels, C.; Andréola, M.; Witvrouw, M.; Christ, F.; Debyser, Z.; Cotelle, P. Design, synthesis, and biological evaluation of a series of 2-hydroxyisoquinoline-1,3(2H,4H)-diones as dual inhibitors of human immunodeficiency virus type 1 integrase and the reverse transcriptase RNase H domain. J. Med. Chem. 2008, 51, 7717-7730.
-
(2008)
J. Med. Chem.
, vol.51
, pp. 7717-7730
-
-
Billamboz, M.1
Bailly, F.2
Barreca, M.L.3
Luca, L.D.4
Mouscadet, J.5
Calmels, C.6
Andréola, M.7
Witvrouw, M.8
Christ, F.9
Debyser, Z.10
Design, C.P.11
-
10
-
-
0028824133
-
Hydroxylated aromatic inhibitors of HIV-1 integrase
-
Burke, J.T.R.; Fesen, M.R.; Mzaumder, A.; Wang, J.; Carothers, A.M.; Grunberger, D.; Driscoll, J.; Kohn, K.; Pormier, Y. Hydroxylated aromatic inhibitors of HIV-1 integrase. J. Med. Chem. 1995, 38, 4171-4178.
-
(1995)
J. Med. Chem.
, vol.38
, pp. 4171-4178
-
-
Burke, J.T.R.1
Fesen, M.R.2
Mzaumder, A.3
Wang, J.4
Carothers, A.M.5
Grunberger, D.6
Driscoll, J.7
Kohn, K.8
Pormier, Y.9
-
11
-
-
34447311921
-
And biological evaluation of N-acetyl-beta-aryl-1,2-didehydroethylamines as new HIV-1 RT inhibitors
-
Cheng, P.; Jiang, Z.Y.; Wang, R.R.; Zhang, X.M.; Wang, Q.; Zheng, Y.T.; Zhou, J.; Chen, J.J. Synthesis and biological evaluation of N-acetyl-beta-aryl- 1,2-didehydroethylamines as new HIV-1 RT inhibitors in vitro. Bioorg. Med. Chem. Lett. 2007, 17, 4476-4480.
-
(2007)
In Vitro. Bioorg. Med. Chem. Lett.
, vol.17
, pp. 4476-4480
-
-
Cheng, P.1
Jiang, Z.Y.2
Wang, R.R.3
Zhang, X.M.4
Wang, Q.5
Zheng, Y.T.6
Zhou, J.7
Synthesis, J.C.J.8
-
12
-
-
41149092492
-
1-Aryltetrahydroisoquinolines as active anti-HIV agents
-
Cheng, P.; Huang, N.; Jiang, Z.Y.; Zhang, Q.; Zheng, Y.T.; Chen, J.J.; Zhang, X.M.; Ma, Y.B. 1-Aryltetrahydroisoquinolines as active anti-HIV agents in vitro. Bioorg. Med. Chem. Lett. 2008, 18, 2475-2478.
-
(2008)
In Vitro. Bioorg. Med. Chem. Lett.
, vol.18
, pp. 2475-2478
-
-
Cheng, P.1
Huang, N.2
Jiang, Z.Y.3
Zhang, Q.4
Zheng, Y.T.5
Chen, J.J.6
Zhang, X.M.7
Ma, Y.B.8
-
13
-
-
45249087047
-
Anti-HBV and HIV-1 alkaloids from Pericampylus glaucus
-
Yan, M.H.; Cheng, P.; Jiang, Z.Y.; Ma, Y.B.; Zhang, X.M.; Zhang, F.X.; Yang, L.M.; Zheng, Y.T.; Chen, J.J. Periglaucines A-D, anti-HBV and HIV-1 alkaloids from Pericampylus glaucus. J. Nat. Prod. 2008, 71, 760-763.
-
(2008)
J. Nat. Prod.
, vol.71
, pp. 760-763
-
-
Yan, M.H.1
Cheng, P.2
Jiang, Z.Y.3
Ma, Y.B.4
Zhang, X.M.5
Zhang, F.X.6
Yang, L.M.7
Zheng, Y.T.8
Chen Periglaucines, J.J.A.-D.9
-
14
-
-
5144232449
-
Zinc coupling potentiates anti-HIV-1 activity of baicalin
-
Wang, Q.; Wang, Y.Y.; Pu, S.P.; Zheng, Y.T. Zinc coupling potentiates anti-HIV-1 activity of baicalin. Biochem. Biophys. Res. Commun. 2004, 324, 605-610.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.324
, pp. 605-610
-
-
Wang, Q.1
Wang, Y.Y.2
Pu, S.P.3
Zheng, Y.T.4
-
15
-
-
33644807569
-
Design, synthesis and biological evaluations of novel oxindoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. Part I
-
DOI 10.1016/j.bmcl.2006.01.073, PII S0960894X06001119
-
Jiang, T.; Kuhen, K.L.; Wolff, K.; Yin, H.; Bieza, K.; Caldwell, J.; Bursulaya, B.; Wu, T.Y.; He, Y. Design, synthesis and biological evaluations of novel oxindoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. Part I. Bioorg. Med. Chem. Lett. 2006, 16, 2105-2108. (Pubitemid 43351059)
-
(2006)
Bioorganic and Medicinal Chemistry Letters
, vol.16
, Issue.8
, pp. 2105-2108
-
-
Jiang, T.1
Kuhen, K.L.2
Wolff, K.3
Yin, H.4
Bieza, K.5
Caldwell, J.6
Bursulaya, B.7
Wu, T.Y.-H.8
He, Y.9
-
16
-
-
20944432342
-
Computational strategies in discovering novel non-nucleoside inhibitors of HIV-1 RT
-
Barreca, M.L.; Rao, A.; Laura, D.L.; Zappala, M.; Monforte, A.; Maga, G.; Pannecouque, C.; Balzarini, J.; Clercq, E.D.; Chimirri, A.; Monforte, P. Computational strategies in discovering novel non-nucleoside inhibitors of HIV-1 RT. J. Med. Chem. 2005, 48, 3433-3437.
-
(2005)
J. Med. Chem.
, vol.48
, pp. 3433-3437
-
-
Barreca, M.L.1
Rao, A.2
Laura, D.L.3
Zappala, M.4
Monforte, A.5
Maga, G.6
Pannecouque, C.7
Balzarini, J.8
Clercq, E.D.9
Chimirri, A.10
Monforte, P.11
|