Structure and function of the l-threonine dehydrogenase (TkTDH) from the hyperthermophilic archaeon Thermococcus kodakaraensis

Journal of Structural Biology

Volumn 168, Issue 2, 2009, Pages 294-304

  Bowyer, A ^a   Mikolajek, H ^b   Stuart, J W ^a   Wood, S P ^a,b   Jamil, F ^c   Rashid, N ^c   Akhtar, M ^a,c   Cooper, J B ^a,b  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^c UNIVERSITY OF THE PUNJAB   (Pakistan)

Author keywords

Channelling; Docking; Multi enzyme complex; Threonine dehydrogenase; X ray crystallography

Indexed keywords

ALCOHOL DEHYDROGENASE; AMINO ACID; BUTYRIC ACID DERIVATIVE; COENZYME A; GLYCINE; LIGASE; MONOMER; NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; OXIDOREDUCTASE; TETRAMER; THREONINE; THREONINE 3 DEHYDROGENASE; UNCLASSIFIED DRUG;

ARTICLE; BETA SHEET; CATALYSIS; COMPLEX FORMATION; CONTROLLED STUDY; DRUG BINDING SITE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME STABILITY; ENZYME STRUCTURE; ENZYME SUBUNIT; ESCHERICHIA COLI; HYPERTHERMOPHILIC ARCHAEON; MOLECULAR DOCKING; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN MOTIF; SEQUENCE HOMOLOGY; THERMOCOCCUS; THERMOCOCCUS KODAKARAENSIS; X RAY CRYSTALLOGRAPHY;

ALCOHOL OXIDOREDUCTASES; AMINO ACID SEQUENCE; AMINO ACIDS; BACTERIAL PROTEINS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; KETO ACIDS; MOLECULAR SEQUENCE DATA; NAD; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; SEQUENCE HOMOLOGY, AMINO ACID; THERMOCOCCUS;

ARCHAEA; THERMOCOCCUS KODAKARENSIS;

EID: 70349453952     PISSN: 10478477     EISSN: 10958657     Source Type: Journal    
DOI: 10.1016/j.jsb.2009.07.011     Document Type: Article

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