Investigating a catalytic mechanism of hyperthermophilic L-threonine dehydrogenase from Pyrococcus horikoshii

Journal of Biochemistry

Volumn 144, Issue 1, 2008, Pages 77-85

  Higashi, Noriko ^a   Tanimoto, Koichi ^a   Nishioka, Motomu ^a   Ishikawa, Kazuhiko ^b   Taya, Masahito ^a  

^a OSAKA UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

Activity enhanced mutant; Archaea; Enzymatic kinetics; Proton relay mechanism; Site directed mutagenesis

Indexed keywords

ALCOHOL DEHYDROGENASE; ASPARTIC ACID; GLUTAMINE; HISTIDINE; OXIDOREDUCTASE; THREONINE;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CATALYSIS; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME KINETICS; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SUBSTRATE; NONHUMAN; PROTEIN DOMAIN; PROTON TRANSPORT; PYROCOCCUS HORIKOSHII; SITE DIRECTED MUTAGENESIS;

ALCOHOL OXIDOREDUCTASES; AMINO ACID SEQUENCE; ARCHAEAL PROTEINS; CATALYSIS; KINETICS; MOLECULAR SEQUENCE DATA; MUTATION; PYROCOCCUS HORIKOSHII; SEQUENCE HOMOLOGY, AMINO ACID; ZINC;

PYROCOCCUS HORIKOSHII;

EID: 46849105863     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvn041     Document Type: Article

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