A broad screen for targets of immune complexes decorating arthritic joints highlights deposition of nucleosomes in rheumatoid arthritis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 37, 2009, Pages 15867-15872

  Monach, Paul A ^a,b,g   Hueber, Wolfgang ^c,d   Kessler, Benedikt ^e   Tomooka, Beren H ^c,d   BenBarak, Maya ^c,d   Simmons, Barry P ^b   Wright, John ^b   Thornhill, Thomas S ^b   Monestier, Marc ^f   Ploegh, Hidde ^e   Robinson, William H ^c,d   Mathis, Diane ^a,b,e   Benoist, Christophe ^a,b,e  

^a JOSLIN DIABETES CENTER   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d VA PALO ALTO HEALTH CARE SYSTEM   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

^f TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Autoantibodies; Histones; Mass spectrometry; Proteomics

Indexed keywords

AUTOANTIGEN; IMMUNOGLOBULIN; IMMUNOGLOBULIN G; PEPTIDE; PROTEIN;

AFFINITY CHROMATOGRAPHY; ANTIGEN ANTIBODY COMPLEX; ARTICLE; ARTICULAR CARTILAGE; CLINICAL ARTICLE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; HUMAN; HUMAN TISSUE; IMMUNOGLOBULIN BLOOD LEVEL; INFLAMMATION; JOINT; JOINT PROSTHESIS; MASS SPECTROMETRY; NUCLEOSOME; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN MICROARRAY; PROTEIN PURIFICATION; PROTEOMICS; RHEUMATOID ARTHRITIS; SCREENING TEST; SYNOVECTOMY; SYNOVIUM; TANDEM MASS SPECTROMETRY;

ANTIBODY SPECIFICITY; ANTIGEN-ANTIBODY COMPLEX; ARTHRITIS, RHEUMATOID; AUTOANTIBODIES; AUTOANTIGENS; CASE-CONTROL STUDIES; EXTRACELLULAR MATRIX; HISTONES; HUMANS; IMMUNOGLOBULIN G; IMMUNOHISTOCHEMISTRY; JOINTS; MICROSCOPY, FLUORESCENCE; OSTEOARTHRITIS; PROTEIN ARRAY ANALYSIS; PROTEOMICS; SYNOVIAL MEMBRANE; TANDEM MASS SPECTROMETRY;

ANIMALIA;

EID: 70349445621     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0908032106     Document Type: Article

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