Prevention of Clostridium sordellii lethal toxin-induced apoptotic cell death by tauroursodeoxycholic acid

Biochemistry

Volumn 48, Issue 38, 2009, Pages 9002-9010

  Schulz, Florian ^a   Just, Ingo ^a   Genth, Harald ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN REORGANIZATION; ANTI-APOPTOTIC EFFECTS; ANTIAPOPTOTIC; ANTIAPOPTOTIC ACTIVITIES; APOPTOSIS; APOPTOTIC CELL DEATH; BILE ACID; CELLULAR LEVELS; CULTURED CELL; CYTOPATHIC EFFECT; CYTOTOXIC EFFECTS; GLUCOSYLATION; GTP-BINDING PROTEINS; INDUCED APOPTOSIS; LOW-MOLECULAR WEIGHT; LY294002; MAP KINASE; NEW CONCEPT; PHOSPHOINOSITIDE 3-KINASE; POTENTIAL APPLICATIONS; TOXIGENIC; VIRULENCE FACTORS; VIRULENT STRAINS;

ACIDS; BODY FLUIDS; CELL CULTURE; CELL MEMBRANES; PROTEINS; SIGNALING; TOXIC MATERIALS;

CELL DEATH;

2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CLOSTRIDIUM TOXIN; CLOSTRIDIUM TOXIN TCSH; CLOSTRIDIUM TOXIN TCSL; GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; RAS PROTEIN; RHO FACTOR; TAUROURSODEOXYCHOLIC ACID; UNCLASSIFIED DRUG; VIRULENCE FACTOR; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; BACTERIAL TOXIN; CHROMONE DERIVATIVE; ENZYME INHIBITOR; IMIDAZOLE DERIVATIVE; LETHAL TOXIN LT, CLOSTRIDIUM SORDELLII; MITOGEN ACTIVATED PROTEIN KINASE P38; MORPHOLINE DERIVATIVE; PYRIDINE DERIVATIVE; TAUROCHENODEOXYCHOLIC ACID;

ANIMAL CELL; APOPTOSIS; ARTICLE; CLOSTRIDIUM SORDELLII; CYTOPATHOGENIC EFFECT; CYTOTOXICITY; ENZYME ACTIVATION; GAS GANGRENE; GLYCOSYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANIMAL; BIOLOGICAL MODEL; CELL LINE; CLOSTRIDIUM INFECTION; DRUG ANTAGONISM; DRUG EFFECT; HELA CELL; HUMAN; METABOLISM; PATHOGENICITY; PHYSIOLOGY;

CLOSTRIDIUM SORDELLII;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; BACTERIAL TOXINS; CELL LINE; CHROMONES; CLOSTRIDIUM INFECTIONS; CLOSTRIDIUM SORDELLII; ENZYME ACTIVATION; ENZYME INHIBITORS; HELA CELLS; HUMANS; IMIDAZOLES; MICE; MODELS, BIOLOGICAL; MORPHOLINES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PYRIDINES; RAS PROTEINS; SIGNAL TRANSDUCTION; TAUROCHENODEOXYCHOLIC ACID;

EID: 70349439436     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi900964c     Document Type: Article

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