-
1
-
-
0033924259
-
Rho GTPases as targets of bacterial protein toxins
-
Aktories K., Schmidt G., and Just I. Rho GTPases as targets of bacterial protein toxins. Biol. Chem. 381 (2000) 421-426
-
(2000)
Biol. Chem.
, vol.381
, pp. 421-426
-
-
Aktories, K.1
Schmidt, G.2
Just, I.3
-
2
-
-
0030567981
-
The Ras-related protein Ral is monoglucosylated by Clostridium sordellii lethal toxin
-
Hofmann F., Rex G., Aktories K., and Just I. The Ras-related protein Ral is monoglucosylated by Clostridium sordellii lethal toxin. Biochem. Biophys. Res. Commun. 227 (1996) 77-81
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.227
, pp. 77-81
-
-
Hofmann, F.1
Rex, G.2
Aktories, K.3
Just, I.4
-
3
-
-
0029925007
-
Inactivation of Ras by Clostridium sordellii lethal toxin-catalyzed glucosylation
-
Just I., Selzer J., Hofmann F., Green G.A., and Aktories K. Inactivation of Ras by Clostridium sordellii lethal toxin-catalyzed glucosylation. J. Biol. Chem. 271 (1996) 10149-10153
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 10149-10153
-
-
Just, I.1
Selzer, J.2
Hofmann, F.3
Green, G.A.4
Aktories, K.5
-
4
-
-
15844415779
-
Ras, Rap, and Rac small GTP-binding proteins are targets for Clostridium sordellii lethal toxin glucosylation
-
Popoff M.R., Chaves-Olarte E., Lemichez E., von Eichel-Streiber C., Thelestam M., Chardin P., Cussac D., Antonny B., Chavrier P., Flatau G., Giry M., de Gunzburg J., and Boquet P. Ras, Rap, and Rac small GTP-binding proteins are targets for Clostridium sordellii lethal toxin glucosylation. J. Biol. Chem. 271 (1996) 10217-10224
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 10217-10224
-
-
Popoff, M.R.1
Chaves-Olarte, E.2
Lemichez, E.3
von Eichel-Streiber, C.4
Thelestam, M.5
Chardin, P.6
Cussac, D.7
Antonny, B.8
Chavrier, P.9
Flatau, G.10
Giry, M.11
de Gunzburg, J.12
Boquet, P.13
-
5
-
-
0034877223
-
pH-enhanced cytopathic effects of Clostridium sordellii lethal toxin
-
Qa'Dan M., Spyres L.M., and Ballard J.D. pH-enhanced cytopathic effects of Clostridium sordellii lethal toxin. Infect. Immun. 69 (2001) 5487-5493
-
(2001)
Infect. Immun.
, vol.69
, pp. 5487-5493
-
-
Qa'Dan, M.1
Spyres, L.M.2
Ballard, J.D.3
-
6
-
-
9644272497
-
A phosphatidylserine-binding site in the cytosolic fragment of Clostridium sordellii lethal toxin facilitates glucosylation of membrane-bound Rac and is required for cytotoxicity
-
Mesmin B., Robbe K., Geny B., Luton F., Brandolin G., Popoff M.R., and Antonny B. A phosphatidylserine-binding site in the cytosolic fragment of Clostridium sordellii lethal toxin facilitates glucosylation of membrane-bound Rac and is required for cytotoxicity. J. Biol. Chem. 279 (2004) 49876-49882
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 49876-49882
-
-
Mesmin, B.1
Robbe, K.2
Geny, B.3
Luton, F.4
Brandolin, G.5
Popoff, M.R.6
Antonny, B.7
-
7
-
-
0142155214
-
Lethal toxin from Clostridium sordellii induces apoptotic cell death by disruption of mitochondrial homeostasis in HL-60 cells
-
Petit P., Breard J., Montalescot V., El Hadj N.B., Levade T., Popoff M., and Geny B. Lethal toxin from Clostridium sordellii induces apoptotic cell death by disruption of mitochondrial homeostasis in HL-60 cells. Cell. Microbiol. 5 (2003) 761-771
-
(2003)
Cell. Microbiol.
, vol.5
, pp. 761-771
-
-
Petit, P.1
Breard, J.2
Montalescot, V.3
El Hadj, N.B.4
Levade, T.5
Popoff, M.6
Geny, B.7
-
8
-
-
0032752063
-
Cellular survival: a play in three Akts
-
Datta S.R., Brunet A., and Greenberg M.E. Cellular survival: a play in three Akts. Genes Dev. 13 (1999) 2905-2927
-
(1999)
Genes Dev.
, vol.13
, pp. 2905-2927
-
-
Datta, S.R.1
Brunet, A.2
Greenberg, M.E.3
-
9
-
-
13844273087
-
PI3K-Akt pathway: its functions and alterations in human cancer
-
Osaki M., Oshimura M., and Ito H. PI3K-Akt pathway: its functions and alterations in human cancer. Apoptosis 9 (2004) 667-676
-
(2004)
Apoptosis
, vol.9
, pp. 667-676
-
-
Osaki, M.1
Oshimura, M.2
Ito, H.3
-
10
-
-
0029804116
-
Mechanism of activation of protein kinase B by insulin and IGF-1
-
Alessi D.R., Andjelkovic M., Caudwell B., Cron P., Morrice N., Cohen P., and Hemmings B.A. Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J. 15 (1996) 6541-6551
-
(1996)
EMBO J.
, vol.15
, pp. 6541-6551
-
-
Alessi, D.R.1
Andjelkovic, M.2
Caudwell, B.3
Cron, P.4
Morrice, N.5
Cohen, P.6
Hemmings, B.A.7
-
12
-
-
0347986675
-
Akt inhibits apoptosis downstream of Bid cleavage via a glucose-dependent mechanism involving mitochondrial hexokinases
-
Majewski N., Nogueira V., Robey R., and Hay N. Akt inhibits apoptosis downstream of Bid cleavage via a glucose-dependent mechanism involving mitochondrial hexokinases. Mol. Cell. Biol. 24 (2004) 730-740
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 730-740
-
-
Majewski, N.1
Nogueira, V.2
Robey, R.3
Hay, N.4
-
13
-
-
0035936023
-
The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change
-
Yamaguchi H., and Wang H. The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change. Oncogene 20 (2001) 7779-7786
-
(2001)
Oncogene
, vol.20
, pp. 7779-7786
-
-
Yamaguchi, H.1
Wang, H.2
-
14
-
-
0029587224
-
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
-
Cross D.A., Alessi D.R., Cohen P., Andjelkovich M., and Hemmings B.A. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378 (1995) 785-789
-
(1995)
Nature
, vol.378
, pp. 785-789
-
-
Cross, D.A.1
Alessi, D.R.2
Cohen, P.3
Andjelkovich, M.4
Hemmings, B.A.5
-
15
-
-
0034114105
-
pH-induced conformational changes in Clostridium difficile toxin B
-
Qa'Dan M., Spyres L.M., and Ballard J.D. pH-induced conformational changes in Clostridium difficile toxin B. Infect. Immun. 68 (2000) 2470-2474
-
(2000)
Infect. Immun.
, vol.68
, pp. 2470-2474
-
-
Qa'Dan, M.1
Spyres, L.M.2
Ballard, J.D.3
-
16
-
-
0035159221
-
Cytosolic delivery and characterization of the TcdB glucosylating domain by using a heterologous protein fusion
-
Spyres L.M., Qa'Dan M., Meader A., Tomasek J.J., Howard E.W., and Ballard J.D. Cytosolic delivery and characterization of the TcdB glucosylating domain by using a heterologous protein fusion. Infect. Immun. 69 (2001) 599-601
-
(2001)
Infect. Immun.
, vol.69
, pp. 599-601
-
-
Spyres, L.M.1
Qa'Dan, M.2
Meader, A.3
Tomasek, J.J.4
Howard, E.W.5
Ballard, J.D.6
-
17
-
-
0033976505
-
New method to generate enzymatically deficient Clostridium difficile toxin B as an antigen for immunization
-
Genth H., Selzer J., Busch C., Dumbach J., Hofmann F., Aktories K., and Just I. New method to generate enzymatically deficient Clostridium difficile toxin B as an antigen for immunization. Infect. Immun. 68 (2000) 1094-1101
-
(2000)
Infect. Immun.
, vol.68
, pp. 1094-1101
-
-
Genth, H.1
Selzer, J.2
Busch, C.3
Dumbach, J.4
Hofmann, F.5
Aktories, K.6
Just, I.7
-
18
-
-
2542545910
-
Clostridium sordellii lethal toxin is maintained in a multimeric protein complex
-
Voth D.E., Qa'Dan M., Hamm E.E., Pelfrey J.M., and Ballard J.D. Clostridium sordellii lethal toxin is maintained in a multimeric protein complex. Infect. Immun. 72 (2004) 3366-3372
-
(2004)
Infect. Immun.
, vol.72
, pp. 3366-3372
-
-
Voth, D.E.1
Qa'Dan, M.2
Hamm, E.E.3
Pelfrey, J.M.4
Ballard, J.D.5
-
19
-
-
0034177069
-
Ras effector pathway activation by epidermal growth factor is inhibited in vivo by exoenzyme S ADP-ribosylation of Ras
-
Henriksson M.L., Rosqvist R., Telepnev M., Wolf-Watz H., and Hallberg B. Ras effector pathway activation by epidermal growth factor is inhibited in vivo by exoenzyme S ADP-ribosylation of Ras. Biochem. J. 347 (2000) 217-222
-
(2000)
Biochem. J.
, vol.347
, pp. 217-222
-
-
Henriksson, M.L.1
Rosqvist, R.2
Telepnev, M.3
Wolf-Watz, H.4
Hallberg, B.5
-
20
-
-
20244368521
-
AT514, a cyclic depsipeptide from Serratia marcescens, induces apoptosis of B-chronic lymphocytic leukemia cells: interference with the Akt/NF-kappaB survival pathway
-
Escobar-Diaz E., Lopez-Martin E.M., Hernandez del Cerro M., Puig-Kroger A., Soto-Cerrato V., Montaner B., Giralt E., Garcia-Marco J.A., Perez-Tomas R., and Garcia-Pardo A. AT514, a cyclic depsipeptide from Serratia marcescens, induces apoptosis of B-chronic lymphocytic leukemia cells: interference with the Akt/NF-kappaB survival pathway. Leukemia 19 (2005) 572-579
-
(2005)
Leukemia
, vol.19
, pp. 572-579
-
-
Escobar-Diaz, E.1
Lopez-Martin, E.M.2
Hernandez del Cerro, M.3
Puig-Kroger, A.4
Soto-Cerrato, V.5
Montaner, B.6
Giralt, E.7
Garcia-Marco, J.A.8
Perez-Tomas, R.9
Garcia-Pardo, A.10
-
21
-
-
0036366158
-
YopH prevents monocyte chemoattractant protein 1 expression in macrophages and T-cell proliferation through inactivation of the phosphatidylinositol 3-kinase pathway
-
Sauvonnet N., Lambermont I., van der Bruggen P., and Cornelis G.R. YopH prevents monocyte chemoattractant protein 1 expression in macrophages and T-cell proliferation through inactivation of the phosphatidylinositol 3-kinase pathway. Mol. Microbiol. 45 (2002) 805-815
-
(2002)
Mol. Microbiol.
, vol.45
, pp. 805-815
-
-
Sauvonnet, N.1
Lambermont, I.2
van der Bruggen, P.3
Cornelis, G.R.4
-
22
-
-
0030922964
-
Intracellular targeting of exoenzyme S of Pseudomonas aeruginosa via type III-dependent translocation induces phagocytosis resistance, cytotoxicity, and disruption of actin microfilaments
-
Frithz-Lindsten E., Du Y., Rosqvist R., and Forsberg A. Intracellular targeting of exoenzyme S of Pseudomonas aeruginosa via type III-dependent translocation induces phagocytosis resistance, cytotoxicity, and disruption of actin microfilaments. Mol. Microbiol. 25 (1997) 1125-1139
-
(1997)
Mol. Microbiol.
, vol.25
, pp. 1125-1139
-
-
Frithz-Lindsten, E.1
Du, Y.2
Rosqvist, R.3
Forsberg, A.4
-
23
-
-
0034612636
-
Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation
-
Hoeflich K.P., Luo J., Rubie E.A., Tsao M.S., Jin O., and Woodgett J.R. Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation. Nature 406 (2000) 86-90
-
(2000)
Nature
, vol.406
, pp. 86-90
-
-
Hoeflich, K.P.1
Luo, J.2
Rubie, E.A.3
Tsao, M.S.4
Jin, O.5
Woodgett, J.R.6
-
24
-
-
0040056864
-
p21-activated kinase 1 phosphorylates the death agonist Bad and protects cells from apoptosis
-
Schurmann A., Mooney A.F., Sanders L.C., Sells M.A., Wang H.G., Reed J.C., and Bokoch G.M. p21-activated kinase 1 phosphorylates the death agonist Bad and protects cells from apoptosis. Mol. Cell. Biol. 20 (2000) 453-461
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 453-461
-
-
Schurmann, A.1
Mooney, A.F.2
Sanders, L.C.3
Sells, M.A.4
Wang, H.G.5
Reed, J.C.6
Bokoch, G.M.7
-
25
-
-
0032808154
-
Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria
-
Kennedy S.G., Kandel E.S., Cross T.K., and Hay N. Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria. Mol. Cell. Biol. 19 (1999) 5800-5810
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 5800-5810
-
-
Kennedy, S.G.1
Kandel, E.S.2
Cross, T.K.3
Hay, N.4
-
26
-
-
0035898449
-
Constitutively activated Akt-1 is vital for the survival of human monocyte-differentiated macrophages: role of Mcl-1, independent of nuclear factor (NF)-kappaB, Bad, or caspase activation
-
Liu H., Perlman H., Pagliari L.J., and Pope R.M. Constitutively activated Akt-1 is vital for the survival of human monocyte-differentiated macrophages: role of Mcl-1, independent of nuclear factor (NF)-kappaB, Bad, or caspase activation. J. Exp. Med. 194 (2001) 113-125
-
(2001)
J. Exp. Med.
, vol.194
, pp. 113-125
-
-
Liu, H.1
Perlman, H.2
Pagliari, L.J.3
Pope, R.M.4
-
27
-
-
0035740048
-
Proteolytic cleavage of molecules involved in cell death or survival pathways: a role in the control of apoptosis?
-
Karran L., and Dyer M.J. Proteolytic cleavage of molecules involved in cell death or survival pathways: a role in the control of apoptosis?. Crit. Rev. Eukaryot. Gene Expr. 11 (2001) 269-277
-
(2001)
Crit. Rev. Eukaryot. Gene Expr.
, vol.11
, pp. 269-277
-
-
Karran, L.1
Dyer, M.J.2
-
28
-
-
0032418092
-
Role of Bcl-2 family proteins in apoptosis: apoptosomes or mitochondria?
-
Tsujimoto Y. Role of Bcl-2 family proteins in apoptosis: apoptosomes or mitochondria?. Genes Cells 3 (1998) 697-707
-
(1998)
Genes Cells
, vol.3
, pp. 697-707
-
-
Tsujimoto, Y.1
-
29
-
-
0035903220
-
L form cytochrome c-conducting pores in pure lipid membranes
-
L form cytochrome c-conducting pores in pure lipid membranes. J. Biol. Chem. 276 (2001) 31083-31091
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 31083-31091
-
-
Basanez, G.1
Zhang, J.2
Chau, B.N.3
Maksaev, G.I.4
Frolov, V.A.5
Brandt, T.A.6
Burch, J.7
Hardwick, J.M.8
Zimmerberg, J.9
-
31
-
-
0034123026
-
Cleavage of Bid during cytotoxic drug and UV radiation-induced apoptosis occurs downstream of the point of Bcl-2 action and is catalyzed by caspase-3: a potential feedback loop for amplification of apoptosis-associated mitochondrial cytochrome c release
-
Slee E.A., Keogh S.A., and Martin S.J. Cleavage of Bid during cytotoxic drug and UV radiation-induced apoptosis occurs downstream of the point of Bcl-2 action and is catalyzed by caspase-3: a potential feedback loop for amplification of apoptosis-associated mitochondrial cytochrome c release. Cell Death Differ 7 (2000) 556-565
-
(2000)
Cell Death Differ
, vol.7
, pp. 556-565
-
-
Slee, E.A.1
Keogh, S.A.2
Martin, S.J.3
|