Loss of proteolytically processed filaggrin caused by epidermal deletion of Matriptase/MT-SP1

Journal of Cell Biology

Volumn 163, Issue 4, 2003, Pages 901-910

  List, Karin ^a,f   Szabo, Roman ^a   Wertz, Philip W ^c   Segre, Julie ^b   Haudenschild, Christian C ^d   Kim, Soo Youl ^e   Bugge, Thomas H ^a  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^b NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF IOWA   (United States)

^d Burke Medical Research Institute ^*  (United States)

^e WEILL CORNELL MEDICAL COLLEGE   (United States)

^f FINSEN LABORATORY   (Denmark)

Author keywords

Barrier function; Lipid lamellar bodies; Membrane serine protease; Profilaggrin; Stratum corneum

Indexed keywords

CALCIUM BINDING PROTEIN; FILAGGRIN; MATRIPTASE; PROFILAGGRIN; PROTEIN S 100; SERINE PROTEINASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DESQUAMATION; EMBRYO; EPIDERMIS; GENE DELETION; KERATINOCYTE; MORPHOGENESIS; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING; PROTEOMICS; STRATUM CORNEUM;

ANIMALS; CELL DIFFERENTIATION; DEHYDRATION; EPIDERMIS; EXTRACELLULAR MATRIX; ICHTHYOSIS; INTERMEDIATE FILAMENT PROTEINS; KERATINOCYTES; LIPID METABOLISM; MICE; MICE, KNOCKOUT; MICROSCOPY, ELECTRON; PEPTIDE HYDROLASES; PERMEABILITY; PROTEIN PRECURSORS; S100 PROTEINS; SERINE ENDOPEPTIDASES; SKIN ABNORMALITIES; TRYPSIN;

ANIMALIA;

EID: 0345166962     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200304161     Document Type: Article

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