-
1
-
-
0033909546
-
A general test of association for quantitative traits in families
-
Abecasis GR, Cadon LR, Cookson WO (2000) A general test of association for quantitative traits in families. Am J Hum Genet 66:279-92
-
(2000)
Am J Hum Genet
, vol.66
, pp. 279-292
-
-
Abecasis, G.R.1
Cadon, L.R.2
Cookson, W.O.3
-
2
-
-
33847029992
-
Null mutation sin the filaggrin (FLG) gene determine major susceptibility to early-onset atopic dermatitis that persists into adulthood
-
doi: 10.1038/sj .jid.5700587
-
Barker JN, Palmer CN, Zhao Y, Liao H, Hull PR, Lee SP et al. (2006) Null mutation sin the filaggrin (FLG) gene determine major susceptibility to early-onset atopic dermatitis that persists into adulthood. J Invest Dermatol. doi: 10.1038/sj .jid.5700587
-
(2006)
J Invest Dermatol
-
-
Barker, J.N.1
Palmer, C.N.2
Zhao, Y.3
Liao, H.4
Hull, P.R.5
Lee, S.P.6
-
3
-
-
1842422281
-
The genetics of psoriasis, psoriatic arthritis and atopic dermatitis
-
Bowcock AM, Cookson WO (2004) The genetics of psoriasis, psoriatic arthritis and atopic dermatitis. Hum Mol Genet 13 Spec No 1:R43-55
-
(2004)
Hum Mol Genet
, vol.13
, Issue.SPEC 1
-
-
Bowcock, A.M.1
Cookson, W.O.2
-
4
-
-
0037096834
-
Susceptibility loci for atopic dermatitis on chromosomes 3, 13, 15, 17 and 18 in a Swedish population
-
Bradley M, Soderhall C, Luthman H, Wahlgren CF, Kockum I, Nordenskjold M (2002) Susceptibility loci for atopic dermatitis on chromosomes 3, 13, 15, 17 and 18 in a Swedish population. Hum Mol Genet 11:1539-1548
-
(2002)
Hum Mol Genet
, vol.11
, pp. 1539-1548
-
-
Bradley, M.1
Soderhall, C.2
Luthman, H.3
Wahlgren, C.F.4
Kockum, I.5
Nordenskjold, M.6
-
5
-
-
10244250341
-
The immunogenetics of asthma and eczema: A new focus on the epithelium
-
Cookson W (2004) The immunogenetics of asthma and eczema: a new focus on the epithelium. Nat Rev Immunol 4:978-88
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 978-988
-
-
Cookson, W.1
-
6
-
-
0035072326
-
Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci
-
Cookson WO, Ubhi B, Lawrence R, Abecasis GR, Walley AJ, Cox HE et al. (2001) Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci. Nat Genet 27:372-3
-
(2001)
Nat Genet
, vol.27
, pp. 372-373
-
-
Cookson, W.O.1
Ubhi, B.2
Lawrence, R.3
Abecasis, G.R.4
Walley, A.J.5
Cox, H.E.6
-
7
-
-
0031951481
-
Association of atopic dermatitis to the beta subunit of the high affinity immunoglobulin E receptor
-
Cox HE, Moffatt MF, Faux JA, Walley AJ, Coleman R, Trembath RC et al. (1998) Association of atopic dermatitis to the beta subunit of the high affinity immunoglobulin E receptor. Br J Dermatol 138:182-7
-
(1998)
Br J Dermatol
, vol.138
, pp. 182-187
-
-
Cox, H.E.1
Moffatt, M.F.2
Faux, J.A.3
Walley, A.J.4
Coleman, R.5
Trembath, R.C.6
-
8
-
-
0001498086
-
Atopic eczema in European and Negro West Indian infants in London
-
Davis LR, Marten RH, Sarkany I (1961) Atopic eczema in European and Negro West Indian infants in London. Br J Dermatol 73:410-4
-
(1961)
Br J Dermatol
, vol.73
, pp. 410-414
-
-
Davis, L.R.1
Marten, R.H.2
Sarkany, I.3
-
9
-
-
21644490116
-
Lack of association of SPINK5 polymorphisms with nonsyndromic atopic dermatitis in the population of Northern Germany
-
Folster-Holst R, Stoll M, Koch WA, Hampe J, Christophers E, Schreiber S (2005) Lack of association of SPINK5 polymorphisms with nonsyndromic atopic dermatitis in the population of Northern Germany. Br J Dermatol 152:1365-7
-
(2005)
Br J Dermatol
, vol.152
, pp. 1365-1367
-
-
Folster-Holst, R.1
Stoll, M.2
Koch, W.A.3
Hampe, J.4
Christophers, E.5
Schreiber, S.6
-
10
-
-
0037142609
-
Calgranulins S100A8 and S100A9 are negatively regulated by glucocorticoids in a c-Fos-dependent manner and overexpressed throughout skin carcinogenesis
-
Gebhardt C, Breitenbach U, Tuckermann JP, Dittrich BT, Richter KH, Angel P (2002) Calgranulins S100A8 and S100A9 are negatively regulated by glucocorticoids in a c-Fos-dependent manner and overexpressed throughout skin carcinogenesis. Oncogene 21:4266-76
-
(2002)
Oncogene
, vol.21
, pp. 4266-4276
-
-
Gebhardt, C.1
Breitenbach, U.2
Tuckermann, J.P.3
Dittrich, B.T.4
Richter, K.H.5
Angel, P.6
-
11
-
-
33645401909
-
Skin barrier function and allergic risk
-
Hudson T (2006) Skin barrier function and allergic risk. Nat Genet 38:399-400
-
(2006)
Nat Genet
, vol.38
, pp. 399-400
-
-
Hudson, T.1
-
12
-
-
33745524911
-
Breaking the (un)sound barrier: Filaggrin is a major gene for atopic dermatitis
-
Irvine AD, McLean WH (2006) Breaking the (un)sound barrier: filaggrin is a major gene for atopic dermatitis. J Invest Dermatol 126:1200-2
-
(2006)
J Invest Dermatol
, vol.126
, pp. 1200-1202
-
-
Irvine, A.D.1
McLean, W.H.2
-
13
-
-
0038579516
-
Association of SPINK5 gene polymorphisms with atopic dermatitis in the Japanese population
-
Kato A, Fukai K, Oiso N, Hosomi N, Murakami T, Ishii M (2003) Association of SPINK5 gene polymorphisms with atopic dermatitis in the Japanese population. Br J Dermatol 148:665-9
-
(2003)
Br J Dermatol
, vol.148
, pp. 665-669
-
-
Kato, A.1
Fukai, K.2
Oiso, N.3
Hosomi, N.4
Murakami, T.5
Ishii, M.6
-
14
-
-
0032701911
-
The two calcium-binding proteins, S100A8 and S100A9, are involved in the metabolism of arachidonic acid in human neutrophils
-
Kerkhoff C, Klempt M, Kaever V, Sorg C (1999) The two calcium-binding proteins, S100A8 and S100A9, are involved in the metabolism of arachidonic acid in human neutrophils. J Biol Chem 274:32672-9
-
(1999)
J Biol Chem
, vol.274
, pp. 32672-32679
-
-
Kerkhoff, C.1
Klempt, M.2
Kaever, V.3
Sorg, C.4
-
15
-
-
14844328134
-
SPINK5 polymorphism is associated with disease severity and food allergy in children with atopic dermatitis
-
Kusunoki T, Okafuji I, Yoshioka T, Saito M, Nishikomori R, Heike T et al. (2005) SPINK5 polymorphism is associated with disease severity and food allergy in children with atopic dermatitis. J Allergy Clin Immunol 115:636-8
-
(2005)
J Allergy Clin Immunol
, vol.115
, pp. 636-638
-
-
Kusunoki, T.1
Okafuji, I.2
Yoshioka, T.3
Saito, M.4
Nishikomori, R.5
Heike, T.6
-
16
-
-
0022528787
-
Atopic dermatitis. A genetic-epidemiologic study in a population-based twin sample
-
Larsen FS, Holm NV, Henningsen K (1986) Atopic dermatitis. A genetic-epidemiologic study in a population-based twin sample. J Am Acad Dermatol 15:487-94
-
(1986)
J Am Acad Dermatol
, vol.15
, pp. 487-494
-
-
Larsen, F.S.1
Holm, N.V.2
Henningsen, K.3
-
17
-
-
0033623607
-
A major susceptibility locus for atopic dermatitis maps to chromosome 3q21
-
Lee YA, Wahn U, Kehrt R, Tarani L, Businco L, Gustafsson D et al. (2000) A major susceptibility locus for atopic dermatitis maps to chromosome 3q21. Nat Genet 26:470-3
-
(2000)
Nat Genet
, vol.26
, pp. 470-473
-
-
Lee, Y.A.1
Wahn, U.2
Kehrt, R.3
Tarani, L.4
Businco, L.5
Gustafsson, D.6
-
18
-
-
18944361861
-
Joint modeling of linkage and association: Identifying SNPs responsible for a linkage signal
-
Li M, Boehnke M, Abecasis GR (2005) Joint modeling of linkage and association: identifying SNPs responsible for a linkage signal. Am J Hum Genet 76:934-49
-
(2005)
Am J Hum Genet
, vol.76
, pp. 934-949
-
-
Li, M.1
Boehnke, M.2
Abecasis, G.R.3
-
19
-
-
15844391073
-
A molecular defect in loricrin, the major component of the cornified cell envelope, underlies Vohwinkel's syndrome
-
Maestrini E, Monaco AP, McGrath JA, Ishida-Yamamoto A, Camisa C, Hovnanian A et al. (1996) A molecular defect in loricrin, the major component of the cornified cell envelope, underlies Vohwinkel's syndrome. Nat Genet 13:70-7
-
(1996)
Nat Genet
, vol.13
, pp. 70-77
-
-
Maestrini, E.1
Monaco, A.P.2
McGrath, J.A.3
Ishida-Yamamoto, A.4
Camisa, C.5
Hovnanian, A.6
-
20
-
-
33749315429
-
Filaggrin loss-of-function mutations predispose to phenotypes involved in the atopic march
-
Marenholz I, Nickel R, Ruschendorf F, Schulz F, Esparza-Gordillo J, Kerscher T et al. (2006) Filaggrin loss-of-function mutations predispose to phenotypes involved in the atopic march. J Allergy Clin Immunol 118:866-71
-
(2006)
J Allergy Clin Immunol
, vol.118
, pp. 866-871
-
-
Marenholz, I.1
Nickel, R.2
Ruschendorf, F.3
Schulz, F.4
Esparza-Gordillo, J.5
Kerscher, T.6
-
21
-
-
0027534206
-
Profilaggrin is a major epidermal calcium-binding protein
-
Markova NG, Marekov LN, Chipev CC, Gan SQ, Idler WW, Steinert PM (1993) Profilaggrin is a major epidermal calcium-binding protein. Mol Cell Biol 13:613-25
-
(1993)
Mol Cell Biol
, vol.13
, pp. 613-625
-
-
Markova, N.G.1
Marekov, L.N.2
Chipev, C.C.3
Gan, S.Q.4
Idler, W.W.5
Steinert, P.M.6
-
22
-
-
0035818472
-
Differentially expressed late constituents of the epidermal cornified envelope
-
Marshall D, Hardman MJ, Nield KM, Byrne C (2001) Differentially expressed late constituents of the epidermal cornified envelope. Proc Natl Acad Sci USA 98:13031-6
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 13031-13036
-
-
Marshall, D.1
Hardman, M.J.2
Nield, K.M.3
Byrne, C.4
-
23
-
-
0029932799
-
Genes encoding structural proteins of epidermal cornification and S100 calcium-binding proteins form a gene complex ("epidermal differentiation complex") on human chromosome 1q21
-
Mischke D, Korge BP, Marenholz I, Volz A, Ziegler A (1996) Genes encoding structural proteins of epidermal cornification and S100 calcium-binding proteins form a gene complex ("epidermal differentiation complex") on human chromosome 1q21. J Invest Dermatol 106:989-92
-
(1996)
J Invest Dermatol
, vol.106
, pp. 989-992
-
-
Mischke, D.1
Korge, B.P.2
Marenholz, I.3
Volz, A.4
Ziegler, A.5
-
24
-
-
77956887506
-
A note on a general definition of the coefficient of determination
-
Nagelkerke NJD (1991) A note on a general definition of the coefficient of determination. Biometrika 78:691-2
-
(1991)
Biometrika
, vol.78
, pp. 691-692
-
-
Nagelkerke, N.J.D.1
-
25
-
-
1642307771
-
Association between polymorphisms in the SPINK5 gene and atopic dermatitis in the Japanese
-
Nishio Y, Noguchi E, Shibasaki M, Kamioka M, Ichikawa E, Ichikawa K et al. (2003) Association between polymorphisms in the SPINK5 gene and atopic dermatitis in the Japanese. Genes Immun 4:515-7
-
(2003)
Genes Immun
, vol.4
, pp. 515-517
-
-
Nishio, Y.1
Noguchi, E.2
Shibasaki, M.3
Kamioka, M.4
Ichikawa, E.5
Ichikawa, K.6
-
26
-
-
33645399288
-
Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis
-
Palmer CN, Irvine AD, Terron-Kwiatkowski A, Zhao Y, Liao H, Lee SP et al. (2006) Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis. Nat Genet 38:441-6
-
(2006)
Nat Genet
, vol.38
, pp. 441-446
-
-
Palmer, C.N.1
Irvine, A.D.2
Terron-Kwiatkowski, A.3
Zhao, Y.4
Liao, H.5
Lee, S.P.6
-
27
-
-
12244264435
-
Genetic power calculator: Design of linkage and association genetic mapping studies of complex traits
-
Purcell S, Cherny SS, Sham PC (2003) Genetic power calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics 19:149-50
-
(2003)
Bioinformatics
, vol.19
, pp. 149-150
-
-
Purcell, S.1
Cherny, S.S.2
Sham, P.C.3
-
29
-
-
33749862108
-
Filaggrin loss-of-function variant contributes to atopic dermatitis risk in the population of North Germany
-
Ruether A, Stoll M, Schwarz T, Schreiber S, Folster-Holst R (2006) Filaggrin loss-of-function variant contributes to atopic dermatitis risk in the population of North Germany. Br J Dermatol 155:1093-4
-
(2006)
Br J Dermatol
, vol.155
, pp. 1093-1094
-
-
Ruether, A.1
Stoll, M.2
Schwarz, T.3
Schreiber, S.4
Folster-Holst, R.5
-
30
-
-
0028902751
-
Defects in the barrier
-
Roop D (1995) Defects in the barrier. Science 267:474-5
-
(1995)
Science
, vol.267
, pp. 474-475
-
-
Roop, D.1
-
31
-
-
33746129175
-
Prevalent and rare mutations in the gene encoding filaggrin cause ichthyosis vulgaris and predispose individuals to atopic dermatitis
-
Sandilands A, O' Reagan GM, Liao H, Zhao Y, Terron-Kwiatkowski A, Watson RM et al. (2006) Prevalent and rare mutations in the gene encoding filaggrin cause ichthyosis vulgaris and predispose individuals to atopic dermatitis. J Invest Dermatol 126:1770-5
-
(2006)
J Invest Dermatol
, vol.126
, pp. 1770-1775
-
-
Sandilands, A.1
O' Reagan, G.M.2
Liao, H.3
Zhao, Y.4
Terron-Kwiatkowski, A.5
Watson, R.M.6
-
32
-
-
0027192827
-
Atopic dermatitis: A genetic-epidemiologic study in a population-based twin sample
-
Schultz Larsen F (1993) Atopic dermatitis: a genetic-epidemiologic study in a population-based twin sample. J Am Acad Dermatol 28:719-23
-
(1993)
J Am Acad Dermatol
, vol.28
, pp. 719-723
-
-
Schultz Larsen, F.1
-
33
-
-
0029813505
-
Decreased expression of filaggrin in atopic skin
-
Seguchi T, Cui CY, Kusuda S, Takahashi M, Aisu K, Tezuka T (1996) Decreased expression of filaggrin in atopic skin. Arch Dermatol Res 288:442-6
-
(1996)
Arch Dermatol Res
, vol.288
, pp. 442-446
-
-
Seguchi, T.1
Cui, C.Y.2
Kusuda, S.3
Takahashi, M.4
Aisu, K.5
Tezuka, T.6
-
34
-
-
33644622891
-
Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris
-
Smith FJ, Irvine AD, Terron-Kwiatkowski A, Sandilands A, Campbell LE, Zhao Y et al. (2006) Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris. Nat Genet 38:337-42
-
(2006)
Nat Genet
, vol.38
, pp. 337-342
-
-
Smith, F.J.1
Irvine, A.D.2
Terron-Kwiatkowski, A.3
Sandilands, A.4
Campbell, L.E.5
Zhao, Y.6
-
35
-
-
0027377799
-
Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM)
-
Spielman RS, McGinnis RE, Ewens WJ (1993) Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet 52:506-16
-
(1993)
Am J Hum Genet
, vol.52
, pp. 506-516
-
-
Spielman, R.S.1
McGinnis, R.E.2
Ewens, W.J.3
-
36
-
-
13244284843
-
Large-scale DNA microarray analysis of atopic skin lesions shows overexpression of an epidermal differentiation gene cluster in the alternative pathway and lack of protective gene expression in the cornified envelope
-
Sugiura H, Ebise H, Tazawa T, Tanaka K, Sugiura Y, Uehara M et al. (2005) Large-scale DNA microarray analysis of atopic skin lesions shows overexpression of an epidermal differentiation gene cluster in the alternative pathway and lack of protective gene expression in the cornified envelope. Br J Dermatol 152:146-9
-
(2005)
Br J Dermatol
, vol.152
, pp. 146-149
-
-
Sugiura, H.1
Ebise, H.2
Tazawa, T.3
Tanaka, K.4
Sugiura, Y.5
Uehara, M.6
-
37
-
-
33644553496
-
Peptidoglycan recognition proteins Pglyrp3 and Pglyrp4 are encoded from the epidermal differentiation complex and are candidate genes for the Psors4 locus on chromosome 1q21
-
Sun C, Mathur P, Dupuis J, Tizard R, Ticho B, Crowell T et al. (2006) Peptidoglycan recognition proteins Pglyrp3 and Pglyrp4 are encoded from the epidermal differentiation complex and are candidate genes for the Psors4 locus on chromosome 1q21. Hum Genet 119:113-25
-
(2006)
Hum Genet
, vol.119
, pp. 113-125
-
-
Sun, C.1
Mathur, P.2
Dupuis, J.3
Tizard, R.4
Ticho, B.5
Crowell, T.6
-
38
-
-
0032738116
-
The epidemiology of atopic dermatitis at a tertiary referral skin center in Singapore
-
Tay YK, Khoo BP, Goh CL (1999) The epidemiology of atopic dermatitis at a tertiary referral skin center in Singapore. Asian Pac J Allergy Immunol 17:137-41
-
(1999)
Asian Pac J Allergy Immunol
, vol.17
, pp. 137-141
-
-
Tay, Y.K.1
Khoo, B.P.2
Goh, C.L.3
-
39
-
-
0034785609
-
Gene polymorphism in Netherton and common atopic disease
-
Walley AJ, Chavanas S, Moffatt MF, Esnouf RM, Ubhi B, Lawrence R et al. (2001) Gene polymorphism in Netherton and common atopic disease. Nat Genet 29:175-8
-
(2001)
Nat Genet
, vol.29
, pp. 175-178
-
-
Walley, A.J.1
Chavanas, S.2
Moffatt, M.F.3
Esnouf, R.M.4
Ubhi, B.5
Lawrence, R.6
-
40
-
-
33745353511
-
Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations
-
Weidinger S, Illig T, Baurecht H, Irvine AD, Rodriguez E, Diaz-Lacava A et al. (2006) Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations. J Allergy Clin Immunol 118:214-9
-
(2006)
J Allergy Clin Immunol
, vol.118
, pp. 214-219
-
-
Weidinger, S.1
Illig, T.2
Baurecht, H.3
Irvine, A.D.4
Rodriguez, E.5
Diaz-Lacava, A.6
-
41
-
-
0028076776
-
The UK working party's diagnostic criteria for atopic dermatitis. I. Derivation of a minimum set of discriminators for atopic dermatitis
-
Williams HC, Burney PG, Hay RJ, Archer CB, Shipley MJ, Hunter JJ et al. (1994a) The UK working party's diagnostic criteria for atopic dermatitis. I. Derivation of a minimum set of discriminators for atopic dermatitis. Br J Dermatol 131:383-96
-
(1994)
Br J Dermatol
, vol.131
, pp. 383-396
-
-
Williams, H.C.1
Burney, P.G.2
Hay, R.J.3
Archer, C.B.4
Shipley, M.J.5
Hunter, J.J.6
-
42
-
-
0027983717
-
The UK working party's diagnostic criteria for atopic dermatitis. III. Independent hospital validation
-
Williams HC, Burney PG, Pembroke AC, Hay RJ (1994b) The UK working party's diagnostic criteria for atopic dermatitis. III. Independent hospital validation. Br J Dermatol 131:406-16
-
(1994)
Br J Dermatol
, vol.131
, pp. 406-416
-
-
Williams, H.C.1
Burney, P.G.2
Pembroke, A.C.3
Hay, R.J.4
-
43
-
-
0028869757
-
London-born black Caribbean children are at increased risk of atopic dermatitis
-
Williams HC, Pembroke AC, Forsdyke H, Boodoo G, Hay RJ, Burney PG (1995) London-born black Caribbean children are at increased risk of atopic dermatitis. J Am Acad Dermatol 32:212-7
-
(1995)
J Am Acad Dermatol
, vol.32
, pp. 212-217
-
-
Williams, H.C.1
Pembroke, A.C.2
Forsdyke, H.3
Boodoo, G.4
Hay, R.J.5
Burney, P.G.6
|