메뉴 건너뛰기




Volumn 111, Issue 2, 2009, Pages 428-440

Brain-derived neurotrophic factor facilitates TrkB down-regulation and neuronal injury after status epilepticus in the rat hippocampus

Author keywords

BDNF; Hippocampus; Infusion; Neurotrophin receptors; Pilocarpine; Seizures

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR;

EID: 70349333903     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06342.x     Document Type: Article
Times cited : (32)

References (58)
  • 2
    • 0028090302 scopus 로고
    • The Trk family of neurotrophin receptors
    • Barbacid M. (1994) The Trk family of neurotrophin receptors. J. Neurbiol. 25, 1386 1403.
    • (1994) J. Neurbiol. , vol.25 , pp. 1386-1403
    • Barbacid, M.1
  • 3
    • 54749091291 scopus 로고    scopus 로고
    • Proteolysis of proBDNF Is a Key Regulator in the Formation of Memory
    • Barnes P. Thomas K. L. (2008) Proteolysis of proBDNF Is a Key Regulator in the Formation of Memory. PLoS ONE 3, e3248.
    • (2008) PLoS ONE , vol.3 , pp. 3248
    • Barnes, P.1    Thomas, K.L.2
  • 4
    • 33846101430 scopus 로고    scopus 로고
    • Persistence of long-term memory storage requires a late protein synthesis- and BDNF- dependent phase in the hippocampus
    • Bekinschtein P., Cammarota M., Igaz L. M., Bevilaqua L. R., Izquierdo I. Medina J. H. (2007) Persistence of long-term memory storage requires a late protein synthesis- and BDNF- dependent phase in the hippocampus. Neuron 53, 261 277.
    • (2007) Neuron , vol.53 , pp. 261-277
    • Bekinschtein, P.1    Cammarota, M.2    Igaz, L.M.3    Bevilaqua, L.R.4    Izquierdo, I.5    Medina, J.H.6
  • 6
    • 0033635904 scopus 로고    scopus 로고
    • Neurotrophins: Key regulators of cell fate and cell shape in the vertebrate nervous system
    • Bibel M. Barde Y. A. (2000) Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system. Genes Dev. 14, 1937 2919.
    • (2000) Genes Dev. , vol.14 , pp. 1937-2919
    • Bibel, M.1    Barde, Y.A.2
  • 7
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding
    • Bradford M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal. Biochem. 72, 248 254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 8
    • 0037762690 scopus 로고    scopus 로고
    • Neurotrophins and their receptors: A convergence point for many signalling pathways
    • Chao M. V. (2003) Neurotrophins and their receptors: a convergence point for many signalling pathways. Nat. Rev. Neurosci. 4, 299 309.
    • (2003) Nat. Rev. Neurosci. , vol.4 , pp. 299-309
    • Chao, M.V.1
  • 9
    • 2342446469 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor reduces TrkB protein and mRNA in the normal retina and following optic nerve crush in adult rats
    • Chen H. Weber A. J. (2004) Brain-derived neurotrophic factor reduces TrkB protein and mRNA in the normal retina and following optic nerve crush in adult rats. Brain Res. 1011, 99 106.
    • (2004) Brain Res. , vol.1011 , pp. 99-106
    • Chen, H.1    Weber, A.J.2
  • 10
    • 13144259635 scopus 로고    scopus 로고
    • TrkB signalling inhibits p75-mediated apoptosis induced by nerve growth factor in embryonic proprioceptive neurons
    • Davey F. Davies A. M. (1998) TrkB signalling inhibits p75-mediated apoptosis induced by nerve growth factor in embryonic proprioceptive neurons. Curr. Biol. 8, 915 918.
    • (1998) Curr. Biol. , vol.8 , pp. 915-918
    • Davey, F.1    Davies, A.M.2
  • 11
    • 39649085329 scopus 로고    scopus 로고
    • Time course and mechanism of hippocampal neuronal death in an in vitro model of status epilepticus: Role of NMDA receptor activation and NMDA dependent calcium entry
    • Deshpande L. S., Lou J. K., Mian A., Blair R. E., Attkisson E. Delorenzo R. J. (2008) Time course and mechanism of hippocampal neuronal death in an in vitro model of status epilepticus: role of NMDA receptor activation and NMDA dependent calcium entry. Eur. J. Pharmacol. 583, 73 83.
    • (2008) Eur. J. Pharmacol. , vol.583 , pp. 73-83
    • Deshpande, L.S.1    Lou, J.K.2    Mian, A.3    Blair, R.E.4    Attkisson, E.5    Delorenzo, R.J.6
  • 12
    • 0029946148 scopus 로고    scopus 로고
    • BDNF down-regulates neurotrophin responsiveness, TrkB protein and TrkB mRNA levels in cultured rat hippocampal neurons
    • Frank L., Ventimiglia R., Anderson K., Lindsay R. M. Rudge J. S. (1996) BDNF down-regulates neurotrophin responsiveness, TrkB protein and TrkB mRNA levels in cultured rat hippocampal neurons. Eur. J. Neurosci. 8, 1220 1230.
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 1220-1230
    • Frank, L.1    Ventimiglia, R.2    Anderson, K.3    Lindsay, R.M.4    Rudge, J.S.5
  • 13
    • 0031149621 scopus 로고    scopus 로고
    • Effects of BDNF infusion on the regulation of trkB protein and message in adult rat brain
    • Frank L., Wiegand S. J., Siuciak J. A., Lindsay R. M. Rudge J. S. (1997) Effects of BDNF infusion on the regulation of trkB protein and message in adult rat brain. Exp. Neurol. 145, 62 70.
    • (1997) Exp. Neurol. , vol.145 , pp. 62-70
    • Frank, L.1    Wiegand, S.J.2    Siuciak, J.A.3    Lindsay, R.M.4    Rudge, J.S.5
  • 14
    • 0034279150 scopus 로고    scopus 로고
    • Neurotrophins induce death of hippocampal neurons via the p75 receptor
    • Friedman W. J. (2000) Neurotrophins induce death of hippocampal neurons via the p75 receptor. J. Neurosci. 20, 6340 6346.
    • (2000) J. Neurosci. , vol.20 , pp. 6340-6346
    • Friedman, W.J.1
  • 15
    • 0030600008 scopus 로고    scopus 로고
    • The temporal evolution of neuronal damage from pilocarpine-induced status epilepticus
    • Fujikawa D. G. (1996) The temporal evolution of neuronal damage from pilocarpine-induced status epilepticus. Brain Res. 725, 11 22.
    • (1996) Brain Res. , vol.725 , pp. 11-22
    • Fujikawa, D.G.1
  • 16
    • 0027744156 scopus 로고
    • Seizures-induced changes in neurotrophin expression: Implications for epilepsy
    • Gall C. M. (1993) Seizures-induced changes in neurotrophin expression: implications for epilepsy. Exp. Neurol. 124, 150 166.
    • (1993) Exp. Neurol. , vol.124 , pp. 150-166
    • Gall, C.M.1
  • 18
    • 3242704193 scopus 로고    scopus 로고
    • Conditional deletion of TrkB but not BDNF prevents epileptogenesis in the kindling model
    • He X. P., Kotloski R., Nef S., Luikart B. W., Parada L. F. McNamara J. O. (2004) Conditional deletion of TrkB but not BDNF prevents epileptogenesis in the kindling model. Neuron 43, 31 42.
    • (2004) Neuron , vol.43 , pp. 31-42
    • He, X.P.1    Kotloski, R.2    Nef, S.3    Luikart, B.W.4    Parada, L.F.5    McNamara, J.O.6
  • 19
    • 0028988240 scopus 로고
    • Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus
    • Kang H. Schuman E. M. (1995) Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus. Science 267, 1658 1662.
    • (1995) Science , vol.267 , pp. 1658-1662
    • Kang, H.1    Schuman, E.M.2
  • 20
    • 0030889462 scopus 로고    scopus 로고
    • Ligand-induced down-regulation of trk messenger RNA, protein and tyrosine phosphorylation in rat cortical neurons
    • Knusel B., Gao H., Okazaki T., Yoshida T., Mori N., Hefti F. Kaplan D. R. (1997) Ligand-induced down-regulation of trk messenger RNA, protein and tyrosine phosphorylation in rat cortical neurons. Neuroscience 78, 951 962.
    • (1997) Neuroscience , vol.78 , pp. 951-962
    • Knusel, B.1    Gao, H.2    Okazaki, T.3    Yoshida, T.4    Mori, N.5    Hefti, F.6    Kaplan, D.R.7
  • 21
    • 0028109727 scopus 로고
    • Characterisation of neurotrophin dimers and monomers
    • Kolbeck R., Jungbluth S. Barde Y. A. (1994) Characterisation of neurotrophin dimers and monomers. Eur. J. Biochem. 225, 995 1003.
    • (1994) Eur. J. Biochem. , vol.225 , pp. 995-1003
    • Kolbeck, R.1    Jungbluth, S.2    Barde, Y.A.3
  • 23
    • 0344441260 scopus 로고    scopus 로고
    • Exacerbated status epilepticus and acute cell loss, but no changes in epileptogenesis, in mice with increased brain-derived neurotrophic factor signaling
    • Lahteinen S., Pitkanen A., Koponen E., Saarelainen T. Castren E. (2003) Exacerbated status epilepticus and acute cell loss, but no changes in epileptogenesis, in mice with increased brain-derived neurotrophic factor signaling. Neuroscience 122, 1081 1092.
    • (2003) Neuroscience , vol.122 , pp. 1081-1092
    • Lahteinen, S.1    Pitkanen, A.2    Koponen, E.3    Saarelainen, T.4    Castren, E.5
  • 24
    • 0029086156 scopus 로고
    • Protective effects of brain-derived neurotrophic factor on the development of hippocampal kindling in the rat
    • Larmet Y., Reibel S., Carnahan J., Nawa H., Marescaux C. Depaulis A. (1995) Protective effects of brain-derived neurotrophic factor on the development of hippocampal kindling in the rat. NeuroReport 6, 1937 1941.
    • (1995) NeuroReport , vol.6 , pp. 1937-1941
    • Larmet, Y.1    Reibel, S.2    Carnahan, J.3    Nawa, H.4    Marescaux, C.5    Depaulis, A.6
  • 25
    • 0035976524 scopus 로고    scopus 로고
    • Regulation of cell survival by secreted proneurotrophins
    • Lee R., Kermani P., Teng K. K. Hempstead B. L. (2001) Regulation of cell survival by secreted proneurotrophins. Science 294, 1945 1948.
    • (2001) Science , vol.294 , pp. 1945-1948
    • Lee, R.1    Kermani, P.2    Teng, K.K.3    Hempstead, B.L.4
  • 26
    • 0346219199 scopus 로고    scopus 로고
    • Acute and long-term synaptic modulation by neurotrophins
    • Lu B. (2004) Acute and long-term synaptic modulation by neurotrophins. Prog. Brain Res. 146, 137 150.
    • (2004) Prog. Brain Res. , vol.146 , pp. 137-150
    • Lu, B.1
  • 27
    • 38649128208 scopus 로고    scopus 로고
    • Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF
    • Matsumoto T., Rauskolb S., Polack M., Klose J., Kolbeck R., Korte M. Barde Y. A. (2008) Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF. Nat. Neurosci. 11, 131 133.
    • (2008) Nat. Neurosci. , vol.11 , pp. 131-133
    • Matsumoto, T.1    Rauskolb, S.2    Polack, M.3    Klose, J.4    Kolbeck, R.5    Korte, M.6    Barde, Y.A.7
  • 28
    • 0034192511 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor differentially regulates excitatory and inhibitory synaptic transmission in hippocampal cultures
    • McLean Bolton M., Pittman A. J. Lo D. C. (2000) Brain-derived neurotrophic factor differentially regulates excitatory and inhibitory synaptic transmission in hippocampal cultures. J. Neurosci. 20, 3221 3232.
    • (2000) J. Neurosci. , vol.20 , pp. 3221-3232
    • McLean Bolton, M.1    Pittman, A.J.2    Lo, D.C.3
  • 29
    • 0037451044 scopus 로고    scopus 로고
    • Pro-brain-derived neurotrophic factor is decreased in parietal cortex in Alzheimer's disease
    • Michalski B. Fahnestock M. (2003) Pro-brain-derived neurotrophic factor is decreased in parietal cortex in Alzheimer's disease. Mol. Brain Res. 111, 148 154.
    • (2003) Mol. Brain Res. , vol.111 , pp. 148-154
    • Michalski, B.1    Fahnestock, M.2
  • 32
    • 2142814521 scopus 로고    scopus 로고
    • National Research Council. National Academies Press. Washington, D.C.
    • National Research Council (1996) Guide for the use and care of laboratory animals. National Academies Press, Washington, D.C.
    • (1996) Guide for the Use and Care of Laboratory Animals.
  • 33
    • 10744219632 scopus 로고    scopus 로고
    • Sortilin is essential for proNGF-induced neuronal cell death
    • Nykjaer A., Lee R., Teng K. K. et al. (2004) Sortilin is essential for proNGF-induced neuronal cell death. Nature 427, 843 848.
    • (2004) Nature , vol.427 , pp. 843-848
    • Nykjaer, A.1    Lee, R.2    Teng, K.K.3
  • 35
    • 20744434559 scopus 로고    scopus 로고
    • Precursor form of brain-derived neurotrophic factor and mature brain-derived neurotrophic factor are decreased in the pre-clinical stages of Alzheimer's disease
    • Peng S., Wuu J., Mufson E. J. Fahnestock M. (2005) Precursor form of brain-derived neurotrophic factor and mature brain-derived neurotrophic factor are decreased in the pre-clinical stages of Alzheimer's disease. J. Neurochem. 93, 1412 1421.
    • (2005) J. Neurochem. , vol.93 , pp. 1412-1421
    • Peng, S.1    Wuu, J.2    Mufson, E.J.3    Fahnestock, M.4
  • 36
    • 44649160040 scopus 로고    scopus 로고
    • Brain-derived neurotropic factor and neurogenesis in the adult rat dentate gyrus: Interactions with corticosterone
    • Pinnock S. B. Herbert J. (2008) Brain-derived neurotropic factor and neurogenesis in the adult rat dentate gyrus: interactions with corticosterone. Eur. J. Neurosci., 27, 2493 2500.
    • (2008) Eur. J. Neurosci. , vol.27 , pp. 2493-2500
    • Pinnock, S.B.1    Herbert, J.2
  • 37
    • 0035234670 scopus 로고    scopus 로고
    • Neurotrophins as synaptic modulators
    • Poo M. M. (2001) Neurotrophins as synaptic modulators. Nat. Rev. Neurosci. 2, 24 32.
    • (2001) Nat. Rev. Neurosci. , vol.2 , pp. 24-32
    • Poo, M.M.1
  • 38
    • 0015309163 scopus 로고
    • Modifications of seizure activity by electrical stimulation. II. Motor seizure
    • Racine R. J. (1972) Modifications of seizure activity by electrical stimulation. II. Motor seizure. Electroencephalogr. Clin. Neurophysiol. 32, 281 294.
    • (1972) Electroencephalogr. Clin. Neurophysiol. , vol.32 , pp. 281-294
    • Racine, R.J.1
  • 39
    • 0033566919 scopus 로고    scopus 로고
    • P75 neurotrophin receptor expression is induced in apoptotic neurons after seizure
    • Roux P. P., Colicos M. A., Barker P. A. Kennedy T. E. (1999) p75 neurotrophin receptor expression is induced in apoptotic neurons after seizure. J. Neurosci. 19, 6887 6896.
    • (1999) J. Neurosci. , vol.19 , pp. 6887-6896
    • Roux, P.P.1    Colicos, M.A.2    Barker, P.A.3    Kennedy, T.E.4
  • 40
    • 0032007112 scopus 로고    scopus 로고
    • Endogenous BDNF protein is increased in adult rat hippocampus after a kainic acid induced excitotoxic insult but exogenous BDNF is not neuroprotective
    • Rudge J. S., Pasnikowski E., Corcoran T., Cai N., Achenson A., Anderson K., Lindsay R. M. Wiegand S. J. (1998) Endogenous BDNF protein is increased in adult rat hippocampus after a kainic acid induced excitotoxic insult but exogenous BDNF is not neuroprotective. Exp. Neurol. 149, 398 410.
    • (1998) Exp. Neurol. , vol.149 , pp. 398-410
    • Rudge, J.S.1    Pasnikowski, E.2    Corcoran, T.3    Cai, N.4    Achenson, A.5    Anderson, K.6    Lindsay, R.M.7    Wiegand, S.J.8
  • 41
    • 14844310369 scopus 로고    scopus 로고
    • Increased neurogenesis and the ectopic granule cells after intrahippocampal BDNF infusion in adult rats
    • Scharfman H., Goodman J., Macleod A., Phani S., Antonelli C. Croll S. (2005) Increased neurogenesis and the ectopic granule cells after intrahippocampal BDNF infusion in adult rats. Exp. Neurol. 192, 348 356.
    • (2005) Exp. Neurol. , vol.192 , pp. 348-356
    • Scharfman, H.1    Goodman, J.2    MacLeod, A.3    Phani, S.4    Antonelli, C.5    Croll, S.6
  • 42
    • 0030025387 scopus 로고    scopus 로고
    • Cellular hybridization for BDNF, trkB, and NGF mRNAs and BDNF-immunoreactivity in rat forebrain after pilocarpine-induced status epilepticus
    • Schmidt-Kastner R., Humpel C., Wetmore C. Olson L. (1996) Cellular hybridization for BDNF, trkB, and NGF mRNAs and BDNF-immunoreactivity in rat forebrain after pilocarpine-induced status epilepticus. Exp. Brain Res. 108, 331 347.
    • (1996) Exp. Brain Res. , vol.108 , pp. 331-347
    • Schmidt-Kastner, R.1    Humpel, C.2    Wetmore, C.3    Olson, L.4
  • 43
    • 0034714392 scopus 로고    scopus 로고
    • Fluoro-Jade B: A high affinity fluorescent marker for the localization of neuronal degeneration
    • Schmued L. C. Hopkins K. J. (2000) Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration. Brain Res. 874, 123 130.
    • (2000) Brain Res. , vol.874 , pp. 123-130
    • Schmued, L.C.1    Hopkins, K.J.2
  • 44
    • 0030901162 scopus 로고    scopus 로고
    • Fluoro-Jade: A novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration
    • Schmued L. C., Albertson C. Slikker W. Jr. (1997) Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration. Brain Res. 751, 37 46.
    • (1997) Brain Res. , vol.751 , pp. 37-46
    • Schmued, L.C.1    Albertson, C.2    Slikker Jr., W.3
  • 45
    • 36148973919 scopus 로고    scopus 로고
    • Peripheral lipopolysaccharide administration transiently affects expression of brain-derived neurotrophic factor, corticotropin and proopiomelanocortin in mouse brain
    • Schnydrig S., Korner L., Landweer S., Ernst B., Walker G., Otten U. Kunz D. (2007) Peripheral lipopolysaccharide administration transiently affects expression of brain-derived neurotrophic factor, corticotropin and proopiomelanocortin in mouse brain. Neurosci. Lett. 429, 69 73.
    • (2007) Neurosci. Lett. , vol.429 , pp. 69-73
    • Schnydrig, S.1    Korner, L.2    Landweer, S.3    Ernst, B.4    Walker, G.5    Otten, U.6    Kunz, D.7
  • 46
    • 34247892268 scopus 로고    scopus 로고
    • Spatial memory training modifies the expression of brain-derived neurotrophic factor tyrosine kinase receptors in young and aged rats
    • Silhol M., Arancibia S., Maurice T. Tapia-Arancibia L. (2007) Spatial memory training modifies the expression of brain-derived neurotrophic factor tyrosine kinase receptors in young and aged rats. Neuroscience 146, 962 973.
    • (2007) Neuroscience , vol.146 , pp. 962-973
    • Silhol, M.1    Arancibia, S.2    Maurice, T.3    Tapia-Arancibia, L.4
  • 47
    • 0034708738 scopus 로고    scopus 로고
    • Down-regulation of the neurotrophin receptor TrkB following ligand binding. Evidence for an involvement of the proteasome and differential regulation of TrkA and TrkB
    • Sommerfeld M. T., Schweigreiter R., Barde Y. A. Hoppe E. (2000) Down-regulation of the neurotrophin receptor TrkB following ligand binding. Evidence for an involvement of the proteasome and differential regulation of TrkA and TrkB. J. Biol. Chem. 275, 8982 8990.
    • (2000) J. Biol. Chem. , vol.275 , pp. 8982-8990
    • Sommerfeld, M.T.1    Schweigreiter, R.2    Barde, Y.A.3    Hoppe, E.4
  • 48
    • 0032958070 scopus 로고    scopus 로고
    • Neuroprottective effects of BDNF in seizures during development
    • Tandon P., Yang Y., Das K., Holmes G. L. Stafstrom C. E. (1999) Neuroprottective effects of BDNF in seizures during development. Neuroscience 91, 293 303.
    • (1999) Neuroscience , vol.91 , pp. 293-303
    • Tandon, P.1    Yang, Y.2    Das, K.3    Holmes, G.L.4    Stafstrom, C.E.5
  • 49
    • 20044370999 scopus 로고    scopus 로고
    • ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin
    • Teng H. K., Teng K. K., Lee R. et al. (2005) ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin. J. Neurosci. 25, 5455 5463.
    • (2005) J. Neurosci. , vol.25 , pp. 5455-5463
    • Teng, H.K.1    Teng, K.K.2    Lee, R.3
  • 50
    • 0021742770 scopus 로고
    • Maturation of kainic acid seizure-brain damage syndrome in the rat. I. Clinical, electrographic and metabolic observations
    • DOI 10.1016/0306-4522(84)90288-4
    • Tremblay E., Nitecka L., Berger M. L. Ben-Ari Y. (1984) Maturation of kainic acid seizure-brain damage syndrome in the rat. I. Clinical, electrographic and metabolic observations. Neuroscience 13, 1051 1072. (Pubitemid 15198960)
    • (1984) Neuroscience , vol.13 , Issue.4 , pp. 1051-1072
    • Tremblay, E.1    Nitecka, L.2    Berger, M.L.3    Ben-Ari, Y.4
  • 51
    • 0037072873 scopus 로고    scopus 로고
    • Mechanisms of p75-mediated death of hippocampal neurons. Role of caspases
    • Troy C. M., Friedman J. E. Friedman W. J. (2002) Mechanisms of p75-mediated death of hippocampal neurons. Role of caspases. J. Biol. Chem. 277, 34295 34302.
    • (2002) J. Biol. Chem. , vol.277 , pp. 34295-34302
    • Troy, C.M.1    Friedman, J.E.2    Friedman, W.J.3
  • 52
    • 34248182541 scopus 로고    scopus 로고
    • NT-3 modulates BDNF and proBDNF levels in naïve and kindled rat hippocampus
    • Ullal G. R., Michalski B., Xu B., Racine R. J. Fahnestock M. (2007) NT-3 modulates BDNF and proBDNF levels in naïve and kindled rat hippocampus. Neurochem. Int. 50, 866 871.
    • (2007) Neurochem. Int. , vol.50 , pp. 866-871
    • Ullal, G.R.1    Michalski, B.2    Xu, B.3    Racine, R.J.4    Fahnestock, M.5
  • 53
    • 45049086341 scopus 로고    scopus 로고
    • Status epilepticus induces a TrkB to p75 neurotrophin receptor switch and increases brain-derived neurotrophic factor interaction with p75 neurotrophin receptor: An initial event in neuronal injury induction
    • Unsain N., Nuñez N., Anastasía A. Mascó D. H. (2008) Status epilepticus induces a TrkB to p75 neurotrophin receptor switch and increases brain-derived neurotrophic factor interaction with p75 neurotrophin receptor: an initial event in neuronal injury induction. Neuroscience 154, 978 993.
    • (2008) Neuroscience , vol.154 , pp. 978-993
    • Unsain, N.1    Nuñez, N.2    Anastasía, A.3    Mascó, D.H.4
  • 54
    • 33747051514 scopus 로고    scopus 로고
    • Interaction of survival and death signaling in basal forebrain neurons: Roles of neurotrophins and proneurotrophins
    • Volosin M., Song W., Almeida R. D., Kaplan D. R., Hempstead B. L. Friedman W. J. (2006) Interaction of survival and death signaling in basal forebrain neurons: roles of neurotrophins and proneurotrophins. J. Neurosci. 26, 7756 7766.
    • (2006) J. Neurosci. , vol.26 , pp. 7756-7766
    • Volosin, M.1    Song, W.2    Almeida, R.D.3    Kaplan, D.R.4    Hempstead, B.L.5    Friedman, W.J.6
  • 55
    • 55749104402 scopus 로고    scopus 로고
    • Induction of proneurotrophins and activation of p75NTR mediated apoptosis via neurotrophin receptor-interacting factor in hippocampal neurons after seizures
    • Volosin M., Trotter C., Cragnolini A., Kenchappa R. S., Light M., Hempstead B. L., Carter B. D. Friedman W. J. (2008) Induction of proneurotrophins and activation of p75NTR mediated apoptosis via neurotrophin receptor-interacting factor in hippocampal neurons after seizures. J. Neurosci. 28, 9870 9879.
    • (2008) J. Neurosci. , vol.28 , pp. 9870-9879
    • Volosin, M.1    Trotter, C.2    Cragnolini, A.3    Kenchappa, R.S.4    Light, M.5    Hempstead, B.L.6    Carter, B.D.7    Friedman, W.J.8
  • 56
    • 2942592402 scopus 로고    scopus 로고
    • The effects of brain-derived neurotrophic factor (BDNF) administration on kindling induction, Trk expression and seizure-related morphological changes
    • Xu B., Michalski B., Racine R. J. Fahnestock M. (2004) The effects of brain-derived neurotrophic factor (BDNF) administration on kindling induction, Trk expression and seizure-related morphological changes. Neuroscience 126, 521 531.
    • (2004) Neuroscience , vol.126 , pp. 521-531
    • Xu, B.1    Michalski, B.2    Racine, R.J.3    Fahnestock, M.4
  • 57
    • 10944243551 scopus 로고    scopus 로고
    • Behavioral stress modifies hippocampal synaptic plasticity through corticosterone-induced sustained extracellular signal-regulated kinase/mitogen-activated protein kinase activation
    • Yang C., Huang C. Hsu K. (2004) Behavioral stress modifies hippocampal synaptic plasticity through corticosterone-induced sustained extracellular signal-regulated kinase/mitogen-activated protein kinase activation. J. Neurosci. 24, 11029 11034.
    • (2004) J. Neurosci. , vol.24 , pp. 11029-11034
    • Yang, C.1    Huang, C.2    Hsu, K.3
  • 58
    • 58849092865 scopus 로고    scopus 로고
    • Neuronal release of proBDNF
    • Yang J., Siao C., Nagappan G. et al. (2009) Neuronal release of proBDNF. Nat. Neurosci. 12, 113 115.
    • (2009) Nat. Neurosci. , vol.12 , pp. 113-115
    • Yang, J.1    Siao, C.2    Nagappan, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.