Stability to gastrointestinal enzymes and structure-activity relationship of β-casein-peptides with antihypertensive properties

Peptides

Volumn 30, Issue 10, 2009, Pages 1848-1853

  Quirós, Ana ^a   Contreras, María del Mar ^a   Ramos, Mercedes ^a   Amigo, Lourdes ^a   Recio, Isidra ^a  

^a INSTITUTO DE FERMENTACIONES INDUSTRIALES CSIC   (Spain)

Author keywords

ACE inhibitory peptides; Antihypertensive activity; Competitive inhibitors; Fermented milk; Simulated gastrointestinal digestion

Indexed keywords

ANTIHYPERTENSIVE AGENT; ARGININE; BETA CASEIN; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENZYME; GASTROINTESTINAL ENZYME; GLYCINE; LEUCINE; LEUCYLHISTIDYLLEUCYLPROLYLLEUCYLPROLINE; LEUCYLHISTIDYLLEUCYLPROLYLLEUCYLPROLYLLEUCINE; LEUCYLTHREONYLGLUTAMYLTHREONYLVALYLVALYLVALYLPROLYLPROLYLPHENYLALANINE; LEUCYLVALYLTYROSYLPROLYLPHELALANYLPROLYLGLYCYLPROLYLISOLEUCYLPROLYLASPARAGYLSERYLLEUCYLPROLYLGLUTAMYLASPARAGYLISOLEUCYLPROLYLPROLINE; PANCREAS EXTRACT; PEPSIN A; PEPTIDE DERIVATIVE; PROLINE; UNCLASSIFIED DRUG; VALYLARGINYLGLYCYLPROLYLPHENYLALANYLPROLYLISOLEUCYLISOLEUCYLVALINE; VALYLLEUCYLGLYCYLPROLYLVALYLARGINYLGLYCYLPROLYLPHENYLALANYLPROLINE; VALYLLEUCYLGLYCYLPROLYLVALYLARGINYLGLYCYLPROLYLPHENYLALANYLPROLYLISOLEUCYLISOLEUCYLVALINE; VALYLVALYLVALYLPROLYLPROLYLPHENYLALANINE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; DRUG HYDROLYSIS; DRUG IDENTIFICATION; DRUG STABILITY; ENZYME INHIBITION; FERMENTATION; IC 50; IN VITRO STUDY; MILK; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; ANTIHYPERTENSIVE AGENTS; CASEINS; DIGESTION; FERMENTATION; GASTROINTESTINAL TRACT; MILK; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 70349333712     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2009.06.031     Document Type: Article

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