Keratin 7 promoter selectively targets transgene expression to normal and neoplastic pancreatic ductal cells in vitro and in vivo

FASEB Journal

Volumn 23, Issue 5, 2009, Pages 1366-1375

  Pujal, Judit ^a   Huch, Meritxell ^a,d   José, Anabel ^b   Abasolo, Ibane ^a   Rodolosse, Annie ^a,c   Duch, Alba ^a,c   Sánchez Palazón, Luis ^b   Smith, Frances J D ^e   McLean, W H Irwin ^e   Fillat, Cristina ^a,b,d   Real, Francisco X ^a,c,f  

^a Barcelona Biomedical Research Park   (Spain)

^b CENTRE FOR GENOMIC REGULATION CRG   (Spain)

^c UNIVERSITAT POMPEU FABRA   (Spain)

^d CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES RARAS CIBERER   (Spain)

^e UNIVERSITY OF DUNDEE   (United Kingdom)

^f Centro Nacional de Investigaciones Oncológicas   (Spain)

Author keywords

Adenovirus; Bioluminescent imaging; Cystic fibrosis; Cytokeratins

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; CYTOKERATIN 7; MESSENGER RNA; TRANSCRIPTION FACTOR SP1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CELL SPECIFICITY; CONTROLLED STUDY; FEMALE; GEL MOBILITY SHIFT ASSAY; GENE DELETION; GENE EXPRESSION; GENE SEQUENCE; GENETIC TRANSCRIPTION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOCOMPETENCE; IN VITRO STUDY; IN VIVO STUDY; INTESTINE EPITHELIUM CELL; LUNG ALVEOLUS EPITHELIUM; MOUSE; NONHUMAN; PANCREAS CANCER; PANCREAS DUCT; PRIORITY JOURNAL; TISSUE SPECIFICITY; TRANSGENE; XENOGRAFT;

ADENOVIRIDAE; MURINAE; MUS; MUS MUSCULUS;

ADENOVIRIDAE; ANIMALS; CELL LINE, TUMOR; FEMALE; HUMANS; KERATIN-7; MICE; MICE, TRANSGENIC; PANCREATIC DUCTS; PANCREATIC NEOPLASMS; PROMOTER REGIONS, GENETIC; REGULATORY SEQUENCES, NUCLEIC ACID; SP1 TRANSCRIPTION FACTOR; TRANSGENES;

EID: 70349325617     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.08-115576     Document Type: Article

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