Relating solubility data of parabens in liquid PEG 400 to the behaviour of PEG 4000-parabens solid dispersions

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 73, Issue 2, 2009, Pages 260-268

  Unga, Johan ^a   Tajarobi, Farhad ^a,b   Norder, Ove ^a   Frenning, Göran ^c   Larsson, Anette ^a  

^a CHALMERS UNIVERSITY OF TECHNOLOGY   (Sweden)

^b ASTRAZENECA R AND D   (Sweden)

^c UPPSALA UNIVERSITY   (Sweden)

Author keywords

Differential scanning calorimetry; Polyethylene glycol; Small angle X ray diffraction; Solid dispersions; Solubility; Wide angle X ray diffraction

Indexed keywords

4 HYDROXYBENZOIC ACID ESTER; BUTYL PARABEN; ETHYL PARABEN; MACROGOL 400; METHYL PARABEN; PROPYL PARABEN;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; LIQUID; MELTING POINT; MOLECULAR DYNAMICS; SOLID; SOLUBILITY; THICKNESS; X RAY DIFFRACTION;

CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; DOSAGE FORMS; DRUG CARRIERS; DRUG COMPOUNDING; MOLECULAR CONFORMATION; PARABENS; POLYETHYLENE GLYCOLS; SOLUBILITY; SOLUTIONS; TRANSITION TEMPERATURE; X-RAY DIFFRACTION;

EID: 70349319752     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2009.06.003     Document Type: Article

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