Enantioselective determination of sibutramine and its active metabolites in human plasma

Journal of Pharmaceutical and Biomedical Analysis

Volumn 51, Issue 1, 2010, Pages 264-267

  Kang, Wonku ^a   Bae, Kyoungjin ^a   Noh, Keumhan ^a  

^a Catholic University of Daegu   (South Korea)

Author keywords

Active metabolite; Chiral separation; Human plasma; LC MS MS; Pharmacokinetics; Sibutramine

Indexed keywords

DESMETHYLSIBUTRAMINE DERIVATIVE; DRUG METABOLITE; SIBUTRAMINE; UNCLASSIFIED DRUG;

ADULT; ANALYTIC METHOD; AREA UNDER THE CURVE; ARTICLE; CHIRALITY; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG HALF LIFE; DRUG ISOLATION; ENANTIOSELECTIVITY; FOOD AND DRUG ADMINISTRATION; HUMAN; HUMAN EXPERIMENT; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; PRIORITY JOURNAL; STEREOISOMERISM; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION; VALIDATION STUDY;

ADMINISTRATION, ORAL; ADULT; APPETITE DEPRESSANTS; CHROMATOGRAPHY, LIQUID; CYCLOBUTANES; HUMANS; MALE; STEREOISOMERISM; TANDEM MASS SPECTROMETRY; YOUNG ADULT;

EID: 70349319360     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2009.07.023     Document Type: Article

References (7)

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