Metabolite profile of sibutramine in human urine: A liquid chromatography-electrospray ionization mass spectrometric study

Journal of Mass Spectrometry

Volumn 41, Issue 9, 2006, Pages 1171-1178

  Link, Marek ^a   Hakala, Kati S ^b   Wsól, Vladimír ^a   Kostiainen, Risto ^b   Ketola, Raimo A ^b  

^a Charles University in Prague Faculty of Pharmacy   (Czech Republic)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Carbamoyl glucuronides; Drug metabolism; Metabolite identification; Sibutramine; Tandem mass spectrometry

Indexed keywords

BODY FLUIDS; DRUG PRODUCTS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOMERS; MASS SPECTROMETRY;

CARBAMOYL GLUCURONIDES; DRUG METABOLISM; METABOLITE IDENTIFICATION; SIBUTRAMINE; TANDEM MASS SPECTROMETRY;

METABOLITES;

DIDEMETHYLSIBUTRAMINE; DRUG METABOLITE; HYDROXYDIDEMETHYLSIBUTRAMINE; MONODEMETHYLSIBUTRAMINE; SIBUTRAMINE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DEMETHYLATION; DRUG ELIMINATION; DRUG METABOLISM; DRUG STRUCTURE; DRUG URINE LEVEL; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; HUMAN; ION TRAP MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; URINALYSIS;

ADULT; ANTIDEPRESSIVE AGENTS; BIOTRANSFORMATION; CHROMATOGRAPHY, LIQUID; CYCLOBUTANES; ETHANOL; FEMALE; GLUCURONIDES; HUMANS; HYDROXYLATION; INDICATORS AND REAGENTS; REFERENCE STANDARDS; SOLVENTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 33749021098     PISSN: 10765174     EISSN: 10969888     Source Type: Journal    
DOI: 10.1002/jms.1082     Document Type: Article

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