The stereoselective biotransformation of the anti-obesity drug sibutramine in rat liver microsomes and in primary cultures of rat hepatocytes

Journal of Pharmacy and Pharmacology

Volumn 57, Issue 3, 2005, Pages 405-410

  Link, Marek ^a   Novotná, Romana ^a   Suchanová, Bohumila ^a   Skálová, Lenka ^a   Wsól, Vladimír ^a   Szotáková, Barbora ^a  

^a Charles University in Prague Faculty of Pharmacy   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOBESITY AGENT; DINORSIBUTRAMINE; DRUG METABOLITE; NORSIBUTRAMINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SIBUTRAMINE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL CELL; ARTICLE; BIOTRANSFORMATION; CELL CULTURE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG METABOLISM; DRUG STRUCTURE; DRUG TRANSFORMATION; ENANTIOMER; LIVER CELL; LIVER MICROSOME; MALE; NONHUMAN; OBESITY; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STEREOCHEMISTRY; ULTRAVIOLET RADIATION;

ANIMALS; APPETITE DEPRESSANTS; BIOTRANSFORMATION; CELL CULTURE TECHNIQUES; CELL SURVIVAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLOBUTANES; HEPATOCYTES; MALE; MICROSOMES, LIVER; NADP; RATS; RATS, WISTAR; STEREOISOMERISM;

EID: 14644422551     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/0022357055678     Document Type: Article

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