Renal failure induces telomere shortening in the rat heart

Netherlands Heart Journal

Volumn 17, Issue 5, 2009, Pages 190-194

  Wong, L S M ^a   Windt, W A ^a   Roks, A J ^a   Van Dokkum, R P ^a   Schoemaker, R G ^a   De Zeeuw, D ^a   Henning, R H ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Kidney failure; Myocardial infarction; Telomere

Indexed keywords

CREATININE; DNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE MEASUREMENT; CONTROLLED STUDY; CORONARY ARTERY LIGATION; CREATININE BLOOD LEVEL; DISEASE SEVERITY; FOCAL GLOMERULOSCLEROSIS; HEART INFARCTION SIZE; HEART RATE; HEART WEIGHT; KIDNEY FAILURE; KIDNEY FUNCTION; LEFT CORONARY ARTERY; MALE; NONHUMAN; PROTEINURIA; RAT; SYSTOLIC BLOOD PRESSURE; TELOMERE; UNINEPHRECTOMY;

EID: 70349289424     PISSN: 15685888     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03086245     Document Type: Article

References (31)

1. Weiner DE, Tighiouart H, Amin MG, Stark PC, MacLeod B, Griffith JL, et al. Chronic kidney disease as a risk factor for cardiovascular disease and all-cause mortality: a pooled analysis of community-based studies. J Am Soc Nephrol 2004;15:1307-1315 (Pubitemid 38526012)
2. Amann K, Kronenberg G, Gehlen F, Wessels S, Orth S, Munter K, et al. Cardiac remodelling in experimental renal failure - an immunohistochemical study. Nephrol Dial Transplant 1998;13: 1958-1966 (Pubitemid 28356759)
3. Blackburn EH. Switching and signaling at the telomere. Cell 2001; 106:661-673
4. Chan SR, Blackburn EH. Telomeres and telomerase. Philos Trans R Soc Lond B Biol Sci 2004;359:109-121
5. Artandi SE. Telomeres, telomerase, and human disease. N Engl J Med 2006;355:1195-1197
6. Oh H, Wang SC, Prahash A, Sano M, Moravec CS, Taffet GE, et al. Telomere attrition and Chk2 activation in human heart failure. Proc Natl Acad Sci U S A 2003;100:5378-5383 (Pubitemid 36542713)
7. Leri A, Franco S, Zacheo A, Barlucchi L, Chimenti S, Limana F, et al. Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with p53 upregulation. EMBO J 2003;22:131-139 (Pubitemid 36091276)
8. van Dokkum RP, Eijkelkamp WB, Kluppel AC, Henning RH, van Goor H, Citgez M, et al. Myocardial infarction enhances progressive renal damage in an experimental model for cardio-renal interaction. J Am Soc Nephrol 2004;15:3103-3110 (Pubitemid 39578842)
9. Raij L, Azar S, Keane W. Mesangial immune injury, hypertension, and progressive glomerular damage in Dahl rats. Kidney Int 1984;26:137-143 (Pubitemid 14017051)
10. Cawthon RM. Telomere measurement by quantitative PCR. Nucleic Acids Res 2002;30:e47
11. Hatori N, Havu N, Hofman-Bang C, Clyne N, Pehrsson SK. Myocardial morphology and cardiac function in rats with renal failure. Jpn Circ J 2000;64:606-610 (Pubitemid 30671028)
12. Raine AE, Seymour AM, Roberts AF, Radda GK, Ledingham JG. Impairment of cardiac function and energetics in experimental renal failure. J Clin Invest 1993;92:2934-2940
13. Dikow R, Kihm LP, Zeier M, Kapitza J, Tornig J, Amann K, et al. Increased infarct size in uremic rats: reduced ischemia tolerance? J Am Soc Nephrol 2004;15:1530-1536 (Pubitemid 38679677)
14. van der Harst P, van der Steege G, de Boer RA, Voors AA, Hall AS, Mulder MJ, et al. Telomere length of circulating leukocytes is decreased in patients with chronic heart failure. J Am Coll Cardiol 2007;49:1459-1464 (Pubitemid 46482923)
15. van der Harst P, Wong LS, de Boer RA, Brouilette SW, van der Steege G, Voors AA, et al. Possible association between telomere length and renal dysfunction in patients with chronic heart failure. Am J Cardiol 2008;102:207-210
16. Saretzki G, Murphy MP, von Zglinicki T. MitoQ counteracts telomere shortening and elongates lifespan of fibroblasts under mild oxidative stress. Aging Cell 2003;2:141-143
17. Serra V, von Zglinicki T, Lorenz M, Saretzki G. Extracellular superoxide dismutase is a major antioxidant in human fibroblasts and slows telomere shortening. J Biol Chem 2003;278:6824-6830 (Pubitemid 36800672)
18. Vaziri ND, Ni Z, Oveisi F, Liang K, Pandian R. Enhanced nitric oxide inactivation and protein nitration by reactive oxygen species in renal insufficiency. Hypertension 2002;39:135-141 (Pubitemid 34100448)
19. Oberg BP, McMenamin E, Lucas FL, McMonagle E, Morrow J, Ikizler TA, et al. Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease. Kidney Int 2004;65:1009-1016 (Pubitemid 38251077)
20. von Zglinicki T. Oxidative stress shortens telomeres. Trends Biochem Sci 2002;27:339-344
21. Cao Y, Li H, Mu FT, Ebisui O, Funder JW, Liu JP. Telomerase activation causes vascular smooth muscle cell proliferation in genetic hypertension. FASEB J 2002;16:96-98
22. Ide T, Tsutsui H, Hayashidani S, Kang D, Suematsu N, Nakamura K, et al. Mitochondrial DNA damage and dysfunction associated with oxidative stress in failing hearts after myocardial infarction. Circ Res 2001;88:529-535 (Pubitemid 32240917)
23. Maulik N, Yoshida T, Das DK. Oxidative stress developed during the reperfusion of ischemic myocardium induces apoptosis. Free Radic Biol Med 1998;24:869-875 (Pubitemid 28169576)
24. Koike MK, de Carvalho FC, de Lourdes HM. Bradykinin B2 receptor antagonism attenuates inflammation, mast cell infiltration and fibrosis in remote myocardium after infarction in rats. Clin Exp Pharmacol Physiol 2005;32:1131-1136
25. Sun Y, Zhang JQ, Zhang J, Lamparter S. Cardiac remodeling by fibrous tissue after infarction in rats. J Lab Clin Med 2000;135: 316-323 (Pubitemid 30213547)
26. Dean RG, Balding LC, Candido R, Burns WC, Cao Z, Twigg SM, et al. Connective tissue growth factor and cardiac fibrosis after myocardial infarction. J Histochem Cytochem 2005;53:1245-1256 (Pubitemid 41331123)
27. Wolf WC, Yoshida H, Agata J, Chao L, Chao J. Human tissue kallikrein gene delivery attenuates hypertension, renal injury, and cardiac remodeling in chronic renal failure. Kidney Int 2000;58: 730-739 (Pubitemid 30620022)
28. Nabokov AV, Amann K, Wessels S, Munter K, Wagner J, Ritz E. Endothelin receptor antagonists influence cardiovascular morphology in uremic rats. Kidney Int 1999;55:512-519 (Pubitemid 29082877)
29. Brouilette SW, Moore JS, McMahon AD, Thompson JR, Ford I, Shepherd J, et al. Telomere length, risk of coronary heart disease, and statin treatment in the West of Scotland Primary Prevention Study: a nested case-control study. Lancet 2007;369:107-114 (Pubitemid 46073129)
30. Kurz DJ, Kloeckener-Gruissem B, Akhmedov A, Eberli FR, Buhler I, Berger W, et al. Degenerative aortic valve stenosis, but not coronary disease, is associated with shorter telomere length in the elderly. Arterioscler Thromb Vasc Biol 2006;26:e114-e117 (Pubitemid 44305356)
31. Martin-Ruiz C, Saretzki G, Petrie J, Ladhoff J, Jeyapalan J, Wei W, et al. Stochastic variation in telomere shortening rate causes heterogeneity of human fibroblast replicative life span. J Biol Chem 2004; 279:17826-17833 (Pubitemid 38560550)