Reflectance Confocal Microscopy in the Daily Practice

Seminars in Cutaneous Medicine and Surgery

Volumn 28, Issue 3, 2009, Pages 180-189

  Ahlgrimm Siess, Verena ^a,b   Hofmann Wellenhof, Rainer ^a   Cao, Theresa ^b   Oliviero, Margaret ^b   Scope, Alon ^d   Rabinovitz, Harold S ^b,c  

^a MEDICAL UNIVERSITY OF GRAZ   (Austria)

^b SKIN AND CANCER ASSOCIATES   (United States)

^c UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

dermoscopy; melanoma; nonmelanocytic skin tumors; reflectance confocal microscopy

Indexed keywords

IMIQUIMOD; MELANIN;

ACTINIC KERATOSIS; BASAL CELL CARCINOMA; CONFOCAL MICROSCOPY; DIAGNOSTIC ACCURACY; HISTOPATHOLOGY; HUMAN; IMAGE ANALYSIS; MELANOMA; REFLECTANCE CONFOCAL MICROSCOPY; REVIEW; SKIN BIOPSY; SKIN DEFECT; SKIN PIGMENTATION; SUN EXPOSURE;

ADULT; AGED; AGED, 80 AND OVER; DERMOSCOPY; FEMALE; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MALE; MELANOMA; MICROSCOPY, CONFOCAL; MICROSCOPY, INTERFERENCE; MIDDLE AGED; NEOPLASMS, BASAL CELL; NEVUS; POINT-OF-CARE SYSTEMS; SKIN NEOPLASMS;

EID: 70349266711     PISSN: 10855629     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.sder.2009.06.008     Document Type: Review

References (20)

1. Rajadhyaksha M., Gonzalez S., Zavislan J.M., et al. In vivo confocal scanning laser microscopy of human skin II: Advances in instrumentation and comparison with histology. J Invest Dermatol 113 (1999) 293-303
2. Scope A., Benvenuto-Andrade C., Agero A.L., et al. Correlation of dermoscopic structures of melanocytic lesions to reflectance confocal microscopy. Arch Dermatol 143 (2007) 176-185
3. Rajadhyaksha M., Grossmann M., Esterowiz D., et al. In vivo confocal scanning laser microscopy of human skin: Melanin provides strong contrast. J Invest Dermatol 104 (1995) 946-952
4. Langley R.G.B., Rajadhyaksha M., Dwyer P.J., et al. Confocal scanning laser microscopy of benign and malignant melanocytic lesions in vivo. J Am Acad Dermatol 45 (2001) 365-376
5. Pellacani G., Cesinaro A.M., Longo C., et al. Microscopic in vivo description of cellular architecture of dermoscopic pigment network in nevi and melanomas. Arch Dermatol 141 (2005) 147-154
6. Pellacani G., Cesinaro A.M., and Seidenari S. In vivo assessment of melanocytic nests in nevi and melanomas by reflectance confocal microscopy. Mod Pathol 18 (2005) 469-474
7. Pellacani G., Guitera P., Longo C., et al. The impact of in vivo reflectance confocal microscopy for the diagnostic accuracy of melanoma and equivocal melanocytic lesions. J Invest Dermatol 127 (2007) 2759-2765
8. Segura S., Puig S., Carrera C., et al. Dendritic cells in pigmented basal cell carcinoma. Arch Dermatol 143 (2007) 883-886
9. Langley R.G.B., Burton E., Walsh N., et al. In vivo confocal scanning laser microscopy of benign lentigines: Comparison to conventional histology and in vivo characteristics of lentigo maligna. J Am Acad Dermatol 55 (2006) 88-97
10. Horn M., Gerger A., Ahlgrimm-Siess V., et al. Discrimination of actinic keratoses from normal skin with reflectance mode confocal microscopy. Dermatol Surg 34 (2008) 620-650
11. Ulrich M., Maltusch A., Rius-Diaz F., et al. Clinical applicability of in vivo reflectance confocal microscopy for the diagnosis of actinic keratoses. Dermatol Surg 34 (2008) 1-10
12. Nori S., Rius-Díaz F., Cuevas J., et al. Sensitivity and specificity of reflectance-mode confocal microscopy for in vivo diagnosis of basal cell carcinoma: A multicenter study. J Am Acad Dermatol 51 (2004) 923-930
13. Sauermann K., Gambichler T., Wilmert M., et al. Investigation of basal cell carcinoma by confocal laser scanning microscopy in vivo. Skin Res Technol 8 (2002) 141-147
14. Busam K.J., Hester K., Charles C., et al. Detection of clinically amelanotic malignant melanoma and assessment of its margins by in vivo confocal scanning laser microscopy. Arch Dermatol 137 (2001) 923-929
15. Curiel-Lewandrowski C., Williams C.M., Swindells K.J., et al. Use of in vivo confocal microscopy in malignant melanoma: An aid in diagnosis and assessment of surgical and nonsurgical therapeutic approaches. Arch Dermatol 140 (2004) 1127-1132
16. Torres A., Niemeyer A., Berkes B., et al. 5% Imiquimod cream and reflectance-mode confocal microscopy as adjunct modalities to mohs micrographic surgery for treatment of basal cell carcinoma. Dermatol Surg 30 (2004) 1462-1469
17. Goldgeier M., Fox C.A., Zavislan J.M., et al. Noninvasive imaging, treatment, and microscopic confirmation of clearance of basal cell carcinoma. Dermatol Surg 29 (2003) 205-210
18. Ahlgrimm-Siess V., Horn M., Koller S., et al. Monitoring efficacy of cryotherapy for superficial basal cell carcinomas with in vivo reflectance confocal microscopy: A preliminary study. J Dermatol Sci 53 (2009) 60-64
19. Gerger A., Koller S., Weger W., et al. Sensitivity and specificity of confocal laser-scanning microscopy for in vivo diagnosis of malignant skin tumors. Cancer 107 (2006) 193-200
20. Langley R.G., Walsh N., Sutherland A.E., et al. The diagnostic accuracy of in vivo confocal scanning laser microscopy compared to dermoscopy of benign and malignant melanocytic lesions: A prospective study. Dermatology 215 (2007) 365-372