The elevated expression of calcitonin receptor by cells recruited into the endothelial layer and neo-intima of atherosclerotic plaque

Histochemistry and Cell Biology

Volumn 132, Issue 2, 2009, Pages 181-189

  Wookey, Peter J ^a   Zulli, Anthony ^a   Hare, David L ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Atherosclerosis; Calcitonin receptor; Cardiovascular disease; Immunohistochemistry

Indexed keywords

CALCITONIN RECEPTOR; CD34 ANTIGEN; CHOLESTEROL;

ABDOMINAL AORTA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY; ARTICLE; ATHEROGENIC DIET; ATHEROSCLEROTIC PLAQUE; CARDIOVASCULAR DISEASE; CELL LINEAGE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM CELL; FOAM CELL; HEALING; HEMATOPOIETIC CELL; IMMUNOCOMPETENT CELL; INTIMA; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; STEM CELL; THORACIC AORTA; ANIMAL; ATHEROSCLEROSIS; BIOSYNTHESIS; DISEASE MODEL; IMMUNOHISTOCHEMISTRY; METABOLISM; PATHOLOGY; UPREGULATION;

ORYCTOLAGUS CUNICULUS;

ANIMALS; ATHEROSCLEROSIS; DIET, ATHEROGENIC; DISEASE MODELS, ANIMAL; DOWN-REGULATION; IMMUNOHISTOCHEMISTRY; MALE; RABBITS; RECEPTORS, CALCITONIN; TUNICA INTIMA; UP-REGULATION;

EID: 70349239589     PISSN: 09486143     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00418-009-0600-6     Document Type: Article

References (62)

1. A Aicher M Rentsch K-I Sasaki JW Ellwart F Fandrich R Siebert JP Cooke S Dimmeler C Heeschen 2007 Nonbone marrow-derived circulating progenitor cells contribute to postnatal neovascularization following tissue ischemia Circ Res 100 581 589 17272807 10.1161/01.RES.0000259562.63718.35 1:CAS:528: DC%2BD2sXitFyltrs%3D (Pubitemid 46673268)
2. WG Beamer LR Donahue CJ Rosen DJ Baylink 1996 Genetic variability in adult bone density among inbred strains of mice Bone 18 397 403 8739896 10.1016/8756-3282(96)00047-6 1:STN:280:DyaK28zhvFWkug%3D%3D (Pubitemid 26152301)
3. C Becskei T Riediger D Zund P Wookey TA Lutz 2004 Immunohistochemical mapping of calcitonin receptors in the adult rat brain Brain Res 1030 221 233 15571671 10.1016/j.brainres.2004.10.012 1:CAS:528:DC%2BD2cXhtVantLzE (Pubitemid 39574954)
4. PJ Blower MR Puncher AG Kettle S George S Dorsch A Leak LH Naylor MJ O'Doherty 1998 Iodine-123 salmon calcitonin, an imaging agent for calcitonin receptors: synthesis, biodistribution, metabolism and dosimetry in humans Eur J Nucl Med 25 101 108 9473255 10.1007/s002590050200 1:CAS:528:DyaK1cXhtVWis70%3D (Pubitemid 28130031)
5. A Breyer N Estharabadi M Oki F Ulloa M Nelson-Holte L Lien Y Jiang 2006 Multipotent adult progenitor cell isolation and culture procedures Exp Hematol 34 1596 1601 17046581 10.1016/j.exphem.2006.07.013 1:CAS:528:DC%2BD28XhtVygtrvN (Pubitemid 44548123)
6. AM Burgess 1985 The effect of calcitonin on the prechordal mesoderm, neural plate and neural crest of Xenopus embryos J Anat 140 Pt 1 49 55 4066470 1:CAS:528:DyaL2MXhsVKntr4%3D
7. JH Campbell JL Efendy CL Han GR Campbell 2000 Blood vessels from bone marrow Ann N Y Acad Sci 902 224 229 10865842 1:STN:280:DC%2BD3czisVWlsQ%3D%3D
8. JH Campbell CL Han GR Campbell 2001 Neointimal formation by circulating bone marrow cells Ann N Y Acad Sci 947 18 24 11795265 1:STN:280: DC%2BD38%2FmvF2nsA%3D%3D discussion 24-5
9. S Chigurupati T Kulkarni S Thomas G Shah 2005 Calcitonin stimulates multiple stages of angiogenesis by directly acting on endothelial cells Cancer Res 65 8519 8529 16166333 10.1158/0008-5472.CAN-05-0848 1:CAS:528: DC%2BD2MXhtVShsbfJ (Pubitemid 41330621)
10. J Cornish KE Callon U Bava SA Kamona GJ Cooper IR Reid 2001 Effects of calcitonin, amylin, and calcitonin gene-related peptide on osteoclast development Bone 29 162 168 11502478 10.1016/S8756-3282(01)00494-X 1:CAS:528:DC%2BD3MXlvFWkuro%3D (Pubitemid 32737190)
11. JH Cui K Park SR Park BH Min 2006 Effects of low-intensity ultrasound on chondrogenic differentiation of mesenchymal stem cells embedded in polyglycolic acid: an in vivo study Tissue Eng 12 75 82 16499444 10.1089/ten.2006.12.75 1:CAS:528:DC%2BD28XhslCjtLg%3D
12. R Dacquin RA Davey C Laplace R Levasseur HA Morris SR Goldring S Gebre-Medhin DL Galson JD Zajac G Karsenty 2004 Amylin inhibits bone resorption while the calcitonin receptor controls bone formation in vivo J Cell Biol 164 509 514 14970190 10.1083/jcb.200312135 1:CAS:528:DC%2BD2cXhsFalsr4%3D (Pubitemid 38233312)
13. I Darby O Skalli G Gabbiani 1990 Alpha-smooth muscle actin is transiently expressed by myofibroblasts during experimental wound healing Lab Invest 63 21 29 2197503 1:CAS:528:DyaK3MXktVChtQ%3D%3D
14. K Daub H Langer P Seizer K Stellos AE May P Goyal B Bigalke T Schonberger T Geisler D Siegel-Axel RA Oostendorp S Lindemann M Gawaz 2006 Platelets induce differentiation of human CD34+ progenitor cells into foam cells and endothelial cells FASEB J 20 2559 2561 17077283 10.1096/fj.06-6265fje 1:CAS:528: DC%2BD28Xht1yms7fF (Pubitemid 44953780)
15. RA Davey HE MacLean JF McManus DM Findlay JD Zajac 2004 Genetically modified animal models as tools for studying bone and mineral metabolism J Bone Miner Res 19 882 892 15125787 10.1359/JBMR.040206 (Pubitemid 41103444)
16. RA Davey AG Turner JF McManus WS Chiu F Tjahyono AJ Moore GJ Atkins PH Anderson C Ma V Glatt HE MacLean C Vincent M Bouxsein HA Morris DM Findlay JD Zajac 2008 Calcitonin receptor plays a physiological role to protect against hypercalcemia in mice J Bone Miner Res 23 1182 1193 18627265 10.1359/jbmr.080310 1:CAS:528:DC%2BD1cXpvFyiurc%3D (Pubitemid 352040174)
17. RJ Deans AB Moseley 2000 Mesenchymal stem cells: biology and potential clinical uses Exp Hematol 28 875 884 10989188 10.1016/S0301-472X(00)00482-3 1:CAS:528:DC%2BD3cXmtlOkur8%3D
18. A Desmouliere M Redard I Darby G Gabbiani 1995 Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar Am J Pathol 146 56 66 7856739 1:STN:280:DyaK2M7mtVWhsA%3D%3D
19. A Evdokiou LJ Raggatt GJ Atkins DM Findlay 1999 Calcitonin receptor-mediated growth suppression of HEK-293 cells is accompanied by induction of p21WAF1/CIP1 and G2/M arrest Mol Endocrinol 13 1738 1750 10517675 10.1210/me.13.10.1738 1:CAS:528:DyaK1MXms1Omtrc%3D
20. A Evdokiou LJ Raggatt T Sakai DM Findlay 2000 Identification of a novel calcitonin-response element in the promoter of the human p21WAF1/CIP1 gene J Mol Endocrinol 25 195 206 11013346 10.1677/jme.0.0250195 1:CAS:528: DC%2BD3cXnslKgtbw%3D
21. A Evdokiou A Labrinidis S Bouralexis S Hay DM Findlay 2003 Induction of cell death of human osteogenic sarcoma cells by zoledronic acid resembles anoikis Bone 33 216 228 14499355 10.1016/S8756-3282(03)00223-0 1:CAS:528:DC%2BD3sXnt1Glsbc%3D (Pubitemid 37117133)
22. EI Fomchenko EC Holland 2005 Stem cells and brain cancer Exp Cell Res 306 323 329 15925587 10.1016/j.yexcr.2005.03.007 1:CAS:528:DC%2BD2MXltVKgsL8%3D (Pubitemid 40732756)
23. S Fukada A Uezumi M Ikemoto S Masuda M Segawa N Tanimura H Yamamoto Y Miyagoe-Suzuki S Takeda 2007 Molecular signature of quiescent satellite cells in adult skeletal muscle Stem Cells 25 2448 2459 17600112 10.1634/stemcells.2007- 0019 1:CAS:528:DC%2BD2sXht1CltL%2FM (Pubitemid 47582737)
24. S Gronthos AC Zannettino SJ Hay S Shi SE Graves A Kortesidis PJ Simmons 2003 Molecular and cellular characterisation of highly purified stromal stem cells derived from human bone marrow J Cell Sci 116 1827 1835 12665563 10.1242/jcs.00369 1:CAS:528:DC%2BD3sXktVGgtLs%3D (Pubitemid 36582169)
25. Y Hu Z Zhang E Torsney AR Afzal F Davison B Metzler Q Xu 2004 Abundant progenitor cells in the adventitia contribute to atherosclerosis of vein grafts in ApoE-deficient mice J Clin Invest 113 1258 1265 15124016 1:CAS:528: DC%2BD2cXjvVOqsrg%3D
26. C Jagger A Gallagher T Chambers M Pondel 1999 The porcine calcitonin receptor promoter directs expression of a linked reporter gene in a tissue and developmental specific manner in transgenic mice Endocrinology 140 492 499 9886862 10.1210/en.140.1.492 1:CAS:528:DyaK1MXhtFWqsg%3D%3D (Pubitemid 29011196)
27. C Jagger T Chambers M Pondel 2000 Transgenic mice reveal novel sites of calcitonin receptor gene expression during development Biochem Biophys Res Commun 274 124 129 10903906 10.1006/bbrc.2000.3093 1:CAS:528: DC%2BD3cXkvFarsb8%3D (Pubitemid 30496767)
28. Y Jiang BN Jahagirdar RL Reinhardt RE Schwartz CD Keene XR Ortiz-Gonzalez M Reyes T Lenvik T Lund M Blackstad J Du S Aldrich A Lisberg WC Low DA Largaespada CM Verfaillie 2002 Pluripotency of mesenchymal stem cells derived from adult marrow Nature 418 41 49 12077603 10.1038/nature00870 1:CAS:528:DC%2BD38XltVantrs%3D (Pubitemid 34742565)
29. RN Kaplan RD Riba S Zacharoulis AH Bramley L Vincent C Costa DD MacDonald DK Jin K Shido SA Kerns Z Zhu D Hicklin Y Wu JL Port N Altorki ER Port D Ruggero SV Shmelkov KK Jensen S Rafii D Lyden 2005 VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche Nature 438 820 827 16341007 10.1038/nature04186 1:CAS:528:DC%2BD2MXht1ynsrnL (Pubitemid 41753060)
30. SK Lee SR Goldring JA Lorenzo 1995 Expression of the calcitonin receptor in bone marrow cell cultures and in bone: a specific marker of the differentiated osteoclast that is regulated by calcitonin Endocrinology 136 4572 4581 7664679 10.1210/en.136.10.4572 1:CAS:528:DyaK2MXot1WlsL0%3D
31. HY Lin TL Harris MR Flannery A Arrufo EH Kaji A Gorn JLF Kolakowski HF Lodish SR Goldring 1991 Expression cloning and characterization of a porcine renal calcitonin receptor Science 254 1022 1024 1658940 10.1126/science.1658940 1:CAS:528:DyaK3sXhs1Whsrc%3D
32. EE Moore RE Kuestner SD Stroop FJ Grant SL Matthewes CL Brady PM Sexton DM Findlay 1995 Functionally different isoforms of the human calcitonin receptor result from alternative splicing of the gene transcript Mol Endocrinol 9 959 968 7476993 10.1210/me.9.8.959 1:CAS:528:DyaK2MXnsVGku70%3D
33. L Mori A Bellini MA Stacey M Schmidt S Mattoli 2005 Fibrocytes contribute to the myofibroblast population in wounded skin and originate from the bone marrow Exp Cell Res 304 81 90 15707576 10.1016/j.yexcr.2004.11.011 1:CAS:528:DC%2BD2MXhtFOmurs%3D (Pubitemid 40222079)
34. R Mould MD Pondel 2003 Calcitonin receptor gene expression in K562 chronic myelogenous leukemic cells Cancer Cell Int 3 6 12747809 10.1186/1475-2867-3-6 (Pubitemid 38751079)
35. GC Nicholson JM Moseley PM Sexton FA Mendelsohn TJ Martin 1986 Abundant calcitonin receptors in isolated rat osteoclasts. Biochemical and autoradiographic characterization J Clin Invest 78 355 360 3016026 10.1172/JCI112584 1:CAS:528:DyaL28XltV2isLc%3D
36. S Nygaard R Kuestner E Moore S Stroop 1997 Phosphorylation of the human calcitonin receptor by multiple kinases is localized to the C-terminus J Bone Miner Research 12 1681 1690 10.1359/jbmr.1997.12.10.1681 1:CAS:528: DyaK2sXmvVSqsr8%3D (Pubitemid 27422369)
37. M Peichev AJ Naiyer D Pereira Z Zhu WJ Lane M Williams MC Oz DJ Hicklin L Witte MA Moore S Rafii 2000 Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors Blood 95 952 958 10648408 1:CAS:528:DC%2BD3cXotV2gsA%3D%3D
38. DG Phinney I Isakova 2005 Plasticity and therapeutic potential of mesenchymal stem cells in the nervous system Curr Pharm Des 11 1255 1265 15853682 10.2174/1381612053507495 1:CAS:528:DC%2BD2MXivVCqtLs%3D (Pubitemid 40458271)
39. J Quinn M Morfis M Lam J Elliott V Kartsogiannis E Williams M Gillespie T Martin P Sexton 1999 Calcitonin receptor antibodies in the identification of osteoclasts Bone 25 1 8 10423015 10.1016/S8756-3282(99)00094-0 1:CAS:528:DyaK1MXkvV2ruro%3D (Pubitemid 29322054)
40. R Ross JA Glomset 1973 Atherosclerosis and the arterial smooth muscle cell: proliferation of smooth muscle is a key event in the genesis of the lesions of atherosclerosis Science 180 1332 1339 4350926 10.1126/science.180. 4093.1332 1:STN:280:DyaE3s7pt1Witw%3D%3D
41. P Ruengsakulrach R Sinclair M Komeda J Raman I Gordon B Buxton 1999 Comparative histopathology of radial artery versus internal thoracic artery and risk factors for development of intimal hyperplasia and atherosclerosis Circulation 100 II139 II144 10567293 1:STN:280:DC%2BD3c%2FjslSgsw%3D%3D
42. D Sakai J Mochida T Iwashina T Watanabe T Nakai K Ando T Hotta 2005 Differentiation of mesenchymal stem cells transplanted to a rabbit degenerative disc model: potential and limitations for stem cell therapy in disc regeneration Spine 30 2379 2387 16261113 10.1097/01.brs.0000184365.28481.e3 (Pubitemid 41567599)
43. RE Schwartz M Reyes L Koodie Y Jiang M Blackstad T Lund T Lenvik S Johnson WS Hu CM Verfaillie 2002 Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells J Clin Invest 109 1291 1302 12021244 1:CAS:528:DC%2BD38XjvFClsro%3D (Pubitemid 34546893)
44. GV Segre SR Goldring 1993 Receptors for secretin, calcitonin, parathyroid hormone (PTH)/PTH-related peptide, vasoactive intestinal peptide, glucagonlike peptide 1, growth hormone-releasing hormone, and glucagon belong to a newly discovered G-protein-linked receptor family Trends Endocrinol Metab 4 309 314 18407176 10.1016/1043-2760(93)90071-L 1:CAS:528:DyaK2cXht1Cqsb0%3D (Pubitemid 24009874)
45. M Serafini SJ Dylla M Oki Y Heremans J Tolar Y Jiang SM Buckley B Pelacho TC Burns S Frommer DJ Rossi D Bryder A Panoskaltsis-Mortari MJ O'Shaughnessy M Nelson-Holte GC Fine IL Weissman BR Blazar CM Verfaillie 2007 Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells J Exp Med 204 129 139 17227908 10.1084/jem.20061115 1:CAS:528:DC%2BD2sXhtFGjtrg%3D (Pubitemid 46148763)
46. D Shirley D Marsh G Jordan S McQuaid G Li 2005 Systemic recruitment of osteoblastic cells in fracture healing J Orthop Res 23 1013 1021 16140187 10.1016/j.orthres.2005.01.013 (Pubitemid 41245423)
47. J Shyu D Inoue R Baron W Horne 1996 The deletion of 14 amino acids in the seventh transmembrane domain of a naturally occurring calcitonin receptor isoform alters ligand binding and selectively abolishes coupling to phospholipase C J Biol Chem 271 31127 31134 8940110 10.1074/jbc.271.49.31127 1:CAS:528:DyaK28Xns1WqtLs%3D (Pubitemid 26408553)
48. F Silvestris P Cafforio M De Matteo C Quatraro F Dammacco 2008 Expression and function of the calcitonin receptor by myeloma cells in their osteoclast-like activity in vitro Leuk Res 32 611 623 17714780 10.1016/j.leukres.2007.07.009 1:CAS:528:DC%2BD1cXitlOhsb8%3D (Pubitemid 351248954)
49. RE Simmons JT Hjelle C Mahoney LJ Deftos W Lisker P Kato R Rabkin 1988 Renal metabolism of calcitonin Am J Physiol 254 F593 F600 2833122 1:CAS:528:DyaL1cXlvVeqtbs%3D
50. C Tikellis L Xuereb D Casley G Brasier ME Cooper PJ Wookey 2003 Calcitonin receptor isoforms expressed in the developing rat kidney Kidney Int 63 416 426 12631107 10.1046/j.1523-1755.2003.00754.x 1:CAS:528: DC%2BD3sXht1yrsrY%3D (Pubitemid 36126788)
51. J Tolar M Osborn S Bell R McElmurry L Xia M Riddle A Panoskaltsis-Mortari Y Jiang RS McIvor CH Contag SR Yant MA Kay CM Verfaillie BR Blazar 2005 Real-time in vivo imaging of stem cells following transgenesis by transposition Mol Ther 12 42 48 15963919 10.1016/j.ymthe.2005.02.023 1:CAS:528: DC%2BD2MXlt1Gls7s%3D (Pubitemid 40862355)
52. M Tolcos C Tikellis S Rees M Cooper P Wookey 2003 Ontogeny of calcitonin receptor mRNA and protein in the developing central nervous system of the rat J Comp Neurol 456 29 38 12508311 10.1002/cne.10478 1:CAS:528: DC%2BD3sXpsVKhsg%3D%3D (Pubitemid 36043640)
53. P Wookey A Zulli B Buxton D Hare 2008 Calcitonin receptor immunoreactivity associated with specific cell types in diseased radial and internal mammary arteries Histopathology 52 605 612 18370957 10.1111/j.1365-2559.2008.02979.x 1:STN:280:DC%2BD1c3ht1Khsg%3D%3D
54. Wookey P, Zulli A, Lo C, Hare D, Schwarer A, Darby I, Leung A (2009) Calcitonin receptor (CTR) expression in embryonic, foetal and adult tissues: developmental and pathophysiological implications. In: Hay D, Dickerson I (eds) The calcitonin gene-related peptide family; form, function and future perspectives. Springer, Dordrecht (in press)
55. X Wu L Huang Q Zhou Y Song A Li H Wang M Song 2005 Effect of paclitaxel and mesenchymal stem cells seeding on ex vivo vascular endothelial repair and smooth muscle cells growth J Cardiovasc Pharmacol 46 779 786 16306802 10.1097/01.fjc.0000187940.14102.64 1:CAS:528:DC%2BD2MXht1Cit73F (Pubitemid 44378250)
56. Q Xu Z Zhang F Davison Y Hu 2003 Circulating progenitor cells regenerate endothelium of vein graft atherosclerosis, which is diminished in ApoE-deficient mice Circ Res 93 e76 e86 14512446 10.1161/01.RES.0000097864.24725.60
57. SD Yoo H Jun BS Shin HS Lee MO Park PP Deluca KC Lee 2000 Pharmacokinetic disposition of polyethylene glycol-modified salmon calcitonins in rats Chem Pharm Bull (Tokyo) 48 1921 1924 1:CAS:528:DC%2BD3cXos1eitr0%3D
58. M Zaidi M Pazianas VS Shankar BE Bax CM Bax PJ Bevis C Stevens CL Huang DR Blake BS Moonga, et al. 1993 Osteoclast function and its control Exp Physiol 78 721 739 8311941 1:CAS:528:DyaK2cXitFehsbc%3D
59. A Zulli RE Widdop DL Hare BF Buxton MJ Black 2003 High methionine and cholesterol diet abolishes endothelial relaxation Arterioscler Thromb Vasc Biol 23 1358 1363 12791673 10.1161/01.ATV.0000080686.39871.54 1:CAS:528: DC%2BD3sXlvFaqs7w%3D (Pubitemid 36994522)
60. A Zulli BF Buxton MJ Black DL Hare 2005 CD34 Class III positive cells are present in atherosclerotic plaques of the rabbit model of atherosclerosis Histochem Cell Biol 124 517 522 16177890 10.1007/s00418-005-0072-2 1:CAS:528:DC%2BD2MXht1Cqt7zF (Pubitemid 41661367)
61. A Zulli BF Buxton MJ Black Z Ming A Cameron DL Hare 2006 The immunoquantification of caveolin-1 and eNOS in human and rabbit diseased blood vessels J Histochem Cytochem 54 151 159 16009963 10.1369/jhc.5A6677.2005 1:CAS:528:DC%2BD28Xht12qtro%3D (Pubitemid 43201636)
62. A Zulli BF Buxton MJ Black DL Hare 2008 Embryonic stem cell markers are present within rabbit atherosclerotic plaques Histol Histopathol 23 741 746 18366012