Antibodies blocking adhesion and matrix binding domains of laminin-332 inhibit tumor growth and metastasis in vivo

International Journal of Cancer

Volumn 125, Issue 8, 2009, Pages 1814-1825

  Salo, Sirpa ^a   Boutaud, Ariel ^b   Hansen, Anker Jon ^c   He, Liqun ^d   Sun, Yi ^d   Morales, Sylvia ^b   Venturini, Amy ^b   Martin, Paula ^a   Nokelainen, Pasi ^a   Betsholtz, Christer ^d   Mathiasen, Ida Stenfeldt ^c   Tryggvason, Karl ^d  

^a UNIVERSITY OF OULU   (Finland)

^b BioStratum Incorporated   (United States)

^c NOVO NORDISK A S   (Denmark)

^d KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Basement membranes; Immunotherapy; Laminin; Metastasis

Indexed keywords

ABCIXIMAB; ANTINEOPLASTIC AGENT; COLLAGEN TYPE 7; IMMUNOGLOBULIN G; INTEGRIN; KALININ; LAMININ ALPHA3; LAMININ BETA3; LAMININ GAMMA2; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 4G1; MONOCLONAL ANTIBODY 6C12; MONOCLONAL ANTIBODY 7B2; MONOCLONAL ANTIBODY BM165; MONOCLONAL ANTIBODY CM6; MONOCLONAL ANTIBODY RG13; NEUTRALIZING ANTIBODY; POLYCLONAL ANTIBODY; POLYCLONAL ANTIBODY 1420; POLYCLONAL ANTIBODY 1425; POLYCLONAL ANTIBODY 226; POLYCLONAL ANTIBODY 26; POLYCLONAL ANTIBODY BST; POLYCLONAL ANTIBODY G123; UNCLASSIFIED DRUG; BLOCKING ANTIBODY; CELL ADHESION MOLECULE;

ALPHA CHAIN; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANOIKIS; ANTIBODY DETECTION; ANTIGEN BINDING; APOPTOSIS; ARTICLE; BETA CHAIN; CANCER GROWTH; CANCER IMMUNOTHERAPY; CANCER INHIBITION; CANCER SIZE; CELL ADHESION; CELL INTERACTION; CELL MIGRATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISSOCIATION; DRUG MECHANISM; EPITHELIUM TUMOR; EXTRACELLULAR MATRIX; FEMALE; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; IN VIVO STUDY; LUNG CARCINOMA; LUNG METASTASIS; METASTASIS INHIBITION; MICROARRAY ANALYSIS; MOUSE; MULTIPLE CYCLE TREATMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA; TARGET CELL; ADENOCARCINOMA; ANIMAL; CELL MOTION; CELL PROLIFERATION; DBA MOUSE; DNA MICROARRAY; DRUG EFFECT; GENE EXPRESSION REGULATION; IMMUNOLOGY; IMMUNOTHERAPY; LUNG TUMOR; MALE; METABOLISM; NUDE MOUSE; PATHOLOGY; TUMOR CELL CULTURE;

ADENOCARCINOMA; ANIMALS; ANTIBODIES, BLOCKING; ANTIBODIES, MONOCLONAL; CARCINOMA, SQUAMOUS CELL; CELL ADHESION; CELL ADHESION MOLECULES; CELL MOVEMENT; CELL PROLIFERATION; EXTRACELLULAR MATRIX; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOTHERAPY; LUNG NEOPLASMS; MALE; MICE; MICE, INBRED DBA; MICE, NUDE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; TUMOR CELLS, CULTURED;

EID: 70349231376     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.24532     Document Type: Article

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