-
1
-
-
17044451254
-
A mutant Drosophila homolog of mammalian clock disrupts circadian rhythms and transcription of period and timeless
-
DOI 10.1016/S0092-8674(00)81440-3
-
Allada R., White N. E., So W. V., Hall J. C. Rosbash M. (1998) A mutant Drosophila homolog of mammalian Clock disrupts circadian rhythms and transcription of period and timeless. Cell 93, 791 804. (Pubitemid 28257585)
-
(1998)
Cell
, vol.93
, Issue.5
, pp. 791-804
-
-
Allada, R.1
White, N.E.2
So, W.V.3
Hall, J.C.4
Rosbash, M.5
-
2
-
-
33846102215
-
Regulating a circadian clock's period, phase and amplitude by Phosphorylation: Insights from Drosophila
-
Bae K. Edery I. (2006) Regulating a circadian clock's period, phase and amplitude by Phosphorylation: insights from Drosophila. J. Biochem. 140, 609 617.
-
(2006)
J. Biochem.
, vol.140
, pp. 609-617
-
-
Bae, K.1
Edery, I.2
-
3
-
-
33847787932
-
PDP1epsilon functions downstream of the circadian oscillator to mediate behavioral rhythms
-
Benito J., Zheng H. Hardin P. E. (2007) PDP1epsilon functions downstream of the circadian oscillator to mediate behavioral rhythms. J. Neurosci. 27, 2539 2547.
-
(2007)
J. Neurosci.
, vol.27
, pp. 2539-2547
-
-
Benito, J.1
Zheng, H.2
Hardin, P.E.3
-
4
-
-
0033544692
-
Cycling vrille expression is required for a functional Drosophila clock
-
Blau J. Young M. W. (1999) Cycling vrille expression is required for a functional Drosophila clock. Cell 99, 661 671.
-
(1999)
Cell
, vol.99
, pp. 661-671
-
-
Blau, J.1
Young, M.W.2
-
5
-
-
0037423224
-
Vrille, Pdp1, and dClock form a second feedback loop in the Drosophila circadian clock
-
Cyran S. A., Buchsbaum A. M., Reddy K. L., Lin M. C., Glossop N. R., Hardin P. E., Young M. W., Storti R. V. Blau J. (2003) vrille, Pdp1, and dClock form a second feedback loop in the Drosophila circadian clock. Cell 112, 329 341.
-
(2003)
Cell
, vol.112
, pp. 329-341
-
-
Cyran, S.A.1
Buchsbaum, A.M.2
Reddy, K.L.3
Lin, M.C.4
Glossop, N.R.5
Hardin, P.E.6
Young, M.W.7
Storti, R.V.8
Blau, J.9
-
6
-
-
20044390202
-
The double-time protein kinase regulates the subcellular localization of the Drosophila clock protein period
-
Cyran S. A., Yiannoulos G., Buchsbaum A. M., Saez L., Young M. W. Blau J. (2005) The double-time protein kinase regulates the subcellular localization of the Drosophila clock protein period. J. Neurosci. 25, 5430 5437.
-
(2005)
J. Neurosci.
, vol.25
, pp. 5430-5437
-
-
Cyran, S.A.1
Yiannoulos, G.2
Buchsbaum, A.M.3
Saez, L.4
Young, M.W.5
Blau, J.6
-
7
-
-
0032486432
-
Closing the circadian loop: CLOCK-induced transcription of its own inhibitors per and tim
-
Darlington T. K., Wager-Smith K., Ceriani M. F., Staknis D., Gekakis N., Steeves T. D., Weitz C. J., Takahashi J. S. Kay S. A. (1998) Closing the circadian loop: CLOCK-induced transcription of its own inhibitors per and tim. Science 280, 1599 1603.
-
(1998)
Science
, vol.280
, pp. 1599-1603
-
-
Darlington, T.K.1
Wager-Smith, K.2
Ceriani, M.F.3
Staknis, D.4
Gekakis, N.5
Steeves, T.D.6
Weitz, C.J.7
Takahashi, J.S.8
Kay, S.A.9
-
9
-
-
33847779219
-
Post-translational modifications regulate the ticking of the circadian clock
-
Gallego M. Virshup D. M. (2007) Post-translational modifications regulate the ticking of the circadian clock. Nat. Rev. Mol. Cell Biol. 8, 139 148.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 139-148
-
-
Gallego, M.1
Virshup, D.M.2
-
10
-
-
0033595790
-
Interlocked feedback loops within the Drosophila circadian oscillator
-
Glossop N. R., Lyons L. C. Hardin P. E. (1999) Interlocked feedback loops within the Drosophila circadian oscillator. Science 286, 766 768.
-
(1999)
Science
, vol.286
, pp. 766-768
-
-
Glossop, N.R.1
Lyons, L.C.2
Hardin, P.E.3
-
11
-
-
0037461716
-
VRILLE feeds back to control circadian transcription of Clock in the Drosophila circadian oscillator
-
Glossop N. R., Houl J. H., Zheng H., Ng F. S., Dudek S. M. Hardin P. E. (2003) VRILLE feeds back to control circadian transcription of Clock in the Drosophila circadian oscillator. Neuron 37, 249 261.
-
(2003)
Neuron
, vol.37
, pp. 249-261
-
-
Glossop, N.R.1
Houl, J.H.2
Zheng, H.3
Ng, F.S.4
Dudek, S.M.5
Hardin, P.E.6
-
12
-
-
0037079034
-
The F-box protein slimb controls the levels of clock proteins period and timeless
-
Grima B., Lamouroux A., Chelot E., Papin C., Limbourg-Bouchon B. Rouyer F. (2002) The F-box protein slimb controls the levels of clock proteins period and timeless. Nature 420, 178 182.
-
(2002)
Nature
, vol.420
, pp. 178-182
-
-
Grima, B.1
Lamouroux, A.2
Chelot, E.3
Papin, C.4
Limbourg-Bouchon, B.5
Rouyer, F.6
-
13
-
-
0029965130
-
Regulation of the Drosophila protein timeless suggests a mechanism for resetting the circadian clock by light
-
Hunter-Ensor M., Ousley A. Sehgal A. (1996) Regulation of the Drosophila protein timeless suggests a mechanism for resetting the circadian clock by light. Cell 84, 677 685.
-
(1996)
Cell
, vol.84
, pp. 677-685
-
-
Hunter-Ensor, M.1
Ousley, A.2
Sehgal, A.3
-
14
-
-
33646591926
-
Balance between DBT/CKIepsilon kinase and protein phosphatase activities regulate phosphorylation and stability of Drosophila CLOCK protein
-
Kim E. Y. Edery I. (2006) Balance between DBT/CKIepsilon kinase and protein phosphatase activities regulate phosphorylation and stability of Drosophila CLOCK protein. Proc. Natl Acad. Sci. USA 103, 6178 6183.
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 6178-6183
-
-
Kim, E.Y.1
Edery, I.2
-
15
-
-
0032504041
-
The Drosophila clock gene double-time encodes a protein closely related to human casein kinase Iepsilon
-
Kloss B., Price J. L., Saez L., Blau J., Rothenfluh A., Wesley C. S. Young M. W. (1998) The Drosophila clock gene double-time encodes a protein closely related to human casein kinase Iepsilon. Cell 94, 97 107.
-
(1998)
Cell
, vol.94
, pp. 97-107
-
-
Kloss, B.1
Price, J.L.2
Saez, L.3
Blau, J.4
Rothenfluh, A.5
Wesley, C.S.6
Young, M.W.7
-
16
-
-
0037069671
-
Role for Slimb in the degradation of Drosophila Period protein phosphorylated by Doubletime
-
Ko H. W., Jiang J. Edery I. (2002) Role for Slimb in the degradation of Drosophila Period protein phosphorylated by Doubletime. Nature 420, 673 678.
-
(2002)
Nature
, vol.420
, pp. 673-678
-
-
Ko, H.W.1
Jiang, J.2
Edery, I.3
-
17
-
-
33745503975
-
JETLAG resets the Drosophila circadian clock by promoting light-induced degradation of TIMELESS
-
Koh K., Zheng X. Sehgal A. (2006) JETLAG resets the Drosophila circadian clock by promoting light-induced degradation of TIMELESS. Science 312, 1809 1812.
-
(2006)
Science
, vol.312
, pp. 1809-1812
-
-
Koh, K.1
Zheng, X.2
Sehgal, A.3
-
18
-
-
0015119210
-
Clock mutants of Drosophila melanogaster
-
Konopka R. J. Benzer S. (1971) Clock mutants of Drosophila melanogaster. Proc. Natl Acad. Sci. USA 68, 2112 2116.
-
(1971)
Proc. Natl Acad. Sci. USA
, vol.68
, pp. 2112-2116
-
-
Konopka, R.J.1
Benzer, S.2
-
19
-
-
65949100602
-
A role for the PERIOD:PERIOD homodier in the Drosophila circadian clock
-
Landskron J., Chen K. F., Wolf E. Stanewsky R. (2009) A role for the PERIOD:PERIOD homodier in the Drosophila circadian clock. PLoS Biol. 7, e3.
-
(2009)
PLoS Biol.
, vol.7
, pp. 3
-
-
Landskron, J.1
Chen, K.F.2
Wolf, E.3
Stanewsky, R.4
-
20
-
-
0032191902
-
The Drosophila CLOCK protein undergoes daily rhythms in abundance, phosphorylation, and interactions with the PER-TIM complex
-
Lee C., Bae K. Edery I. (1998) The Drosophila CLOCK protein undergoes daily rhythms in abundance, phosphorylation, and interactions with the PER-TIM complex. Neuron 21, 857 867.
-
(1998)
Neuron
, vol.21
, pp. 857-867
-
-
Lee, C.1
Bae, K.2
Edery, I.3
-
21
-
-
0032778040
-
PER and TIM inhibit the DNA binding activity of a Drosophila CLOCK-CYC/dBMAL1 heterodimer without disrupting formation of the heterodimer: A basis for circadian transcription
-
Lee C., Bae K. Edery I. (1999) PER and TIM inhibit the DNA binding activity of a Drosophila CLOCK-CYC/dBMAL1 heterodimer without disrupting formation of the heterodimer: a basis for circadian transcription. Mol. Cell. Biol. 19, 5316 5325.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 5316-5325
-
-
Lee, C.1
Bae, K.2
Edery, I.3
-
22
-
-
34347332369
-
Functional role of CREB-binding protein in the circadian clock system of Drosophila melanogaster
-
Lim C., Lee J., Choi C., Kim J., Doh E. Choe J. (2007a) Functional role of CREB-binding protein in the circadian clock system of Drosophila melanogaster. Mol. Cell. Biol. 27, 4876 4890.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 4876-4890
-
-
Lim, C.1
Lee, J.2
Choi, C.3
Kim, J.4
Doh, E.5
Choe, J.6
-
23
-
-
35448960398
-
Targeted inhibition of Pdp1epsilon abolishes the circadian behavior of Drosophila melanogaster
-
Lim C., Lee J., Koo E. Choe J. (2007b) Targeted inhibition of Pdp1epsilon abolishes the circadian behavior of Drosophila melanogaster. Biochem. Biophys. Res. Commun. 364, 294 300.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.364
, pp. 294-300
-
-
Lim, C.1
Lee, J.2
Koo, E.3
Choe, J.4
-
24
-
-
0035875069
-
A role for the segment polarity gene shaggy/GSK-3 in the Drosophila circadian clock
-
Martinek S., Inonog S., Manoukian A. S. Young M. W. (2001) A role for the segment polarity gene shaggy/GSK-3 in the Drosophila circadian clock. Cell 105, 769 779.
-
(2001)
Cell
, vol.105
, pp. 769-779
-
-
Martinek, S.1
Inonog, S.2
Manoukian, A.S.3
Young, M.W.4
-
25
-
-
36849020944
-
Drosophila DBT lacking protein kinase activity produces long-period and arrhythmic circadian behavioral and molecular rhythms
-
Muskus M. J., Preuss F., Fan J. Y., Bjes E. S. Price J. L. (2007) Drosophila DBT lacking protein kinase activity produces long-period and arrhythmic circadian behavioral and molecular rhythms. Mol. Cell. Biol. 27, 8049 8064.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 8049-8064
-
-
Muskus, M.J.1
Preuss, F.2
Fan, J.Y.3
Bjes, E.S.4
Price, J.L.5
-
26
-
-
0029989521
-
Light-induced degradation of TIMELESS and entrainment of the Drosophila circadian clock
-
Myers M. P., Wager-Smith K., Rothenfluh-Hilfiker A. Young M. W. (1996) Light-induced degradation of TIMELESS and entrainment of the Drosophila circadian clock. Science 271, 1736 1740.
-
(1996)
Science
, vol.271
, pp. 1736-1740
-
-
Myers, M.P.1
Wager-Smith, K.2
Rothenfluh-Hilfiker, A.3
Young, M.W.4
-
27
-
-
0442319504
-
The doubletime and CKII kinases collaborate to potentiate Drosophila per transcriptional repressor activity
-
Nawathean P. Rosbash M. (2004) The doubletime and CKII kinases collaborate to potentiate Drosophila PER transcriptional repressor activity. Mol. Cell 13, 213 223.
-
(2004)
Mol. Cell
, vol.13
, pp. 213-223
-
-
Nawathean, P.1
Rosbash, M.2
-
28
-
-
14844327076
-
Assaying the Drosophila negative feedback loop with RNA interference in S2 cells
-
Nawathean P., Menet J. S. Rosbach M. (2005) Assaying the Drosophila negative feedback loop with RNA interference in S2 cells. Methods Enzymol. 393, 610 622.
-
(2005)
Methods Enzymol.
, vol.393
, pp. 610-622
-
-
Nawathean, P.1
Menet, J.S.2
Rosbach, M.3
-
29
-
-
0346725938
-
Drosophila doubletime mutations which either shorten or lengthen the period of circadian rhythms decrease the protein kinase activity of casein kinase i
-
Preuss F., Fan J. Y., Kalive M., Bao S., Schuenemann E., Bjes E. S. Price J. L. (2004) Drosophila doubletime mutations which either shorten or lengthen the period of circadian rhythms decrease the protein kinase activity of casein kinase I. Mol. Cell. Biol. 24, 886 898.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 886-898
-
-
Preuss, F.1
Fan, J.Y.2
Kalive, M.3
Bao, S.4
Schuenemann, E.5
Bjes, E.S.6
Price, J.L.7
-
30
-
-
0034667556
-
Two novel doubletime mutants alter circadian properties and eliminate the delay between RNA and protein in Drosophila
-
Suri V., Hall J. C. Rosbash M. (2000) Two novel doubletime mutants alter circadian properties and eliminate the delay between RNA and protein in Drosophila. J. Neurosci. 20, 7547 7555.
-
(2000)
J. Neurosci.
, vol.20
, pp. 7547-7555
-
-
Suri, V.1
Hall, J.C.2
Rosbash, M.3
-
31
-
-
33645010948
-
PER-dependent rhythms in CLK phosphorylation and E-box binding regulate circadian transcription
-
Yu W., Zheng H., Houl J. H., Dauwalder B. Hardin P. E. (2006) PER-dependent rhythms in CLK phosphorylation and E-box binding regulate circadian transcription. Genes Dev. 20, 723 733.
-
(2006)
Genes Dev.
, vol.20
, pp. 723-733
-
-
Yu, W.1
Zheng, H.2
Houl, J.H.3
Dauwalder, B.4
Hardin, P.E.5
-
32
-
-
62849110192
-
DOUBLETIME plays a non-catalytic role to mediate CLOCK phosphorylation and repress CLOCK-dependent transcription within the Drosophila circadian clock
-
Yu W., Zheng H., Price J. L. Hardin P. E. (2009) DOUBLETIME plays a non-catalytic role to mediate CLOCK phosphorylation and repress CLOCK-dependent transcription within the Drosophila circadian clock. Mol. Cell. Biol. 29, 1452 1458.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 1452-1458
-
-
Yu, W.1
Zheng, H.2
Price, J.L.3
Hardin, P.E.4
-
33
-
-
45149098327
-
Probing the relative importance of molecular oscillations in the circadian clock
-
Zheng X. Sehgal A. (2008) Probing the relative importance of molecular oscillations in the circadian clock. Genetics 178, 1147 1155.
-
(2008)
Genetics
, vol.178
, pp. 1147-1155
-
-
Zheng, X.1
Sehgal, A.2
|