Retinoid X receptor-α mediates (R)-flurbiprofen's effect on the levels of Alzheimer's β-amyloid

Journal of Neurochemistry

Volumn 111, Issue 1, 2009, Pages 142-149

  You, Xiaoqing ^a,b   Zhang, Yun Wu ^a,c   Chen, Yaomin ^c   Huang, Xiumei ^a,c   Xu, Raymond ^c   Cao, Xihua ^c   Chen, Jiebo ^c   Liu, Yun ^c   Zhang, Xiaokun ^a,c   Xu, Huaxi ^a,c  

^a XIAMEN UNIVERSITY   (China)

^b FUJIAN MEDICAL UNIVERSITY   (China)

^c BURNHAM INSTITUTE   (United States)

Author keywords

amyloid; (R) flurbiprofen; Alzheimer's disease; Non steroidal anti inflammatory drug; Retinoid X receptor

Indexed keywords

AMYLOID BETA PROTEIN; CELL NUCLEUS RECEPTOR; FLURBIPROFEN; NONSTEROID ANTIINFLAMMATORY AGENT; RETINOID X RECEPTOR ALPHA;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ENANTIOMER; HUMAN; HUMAN CELL; INTRACELLULAR SPACE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEIN SYNTHESIS;

AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPARTIC ENDOPEPTIDASES; BIOTINYLATION; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLURBIPROFEN; GENE EXPRESSION REGULATION; HUMANS; IMMUNOPRECIPITATION; MICE; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; PROTEIN BINDING; RECEPTORS, NOTCH; RETINOID X RECEPTORS; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 70349207107     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06312.x     Document Type: Article

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