Linear epitope mapping by native mass spectrometry

Analytical Biochemistry

Volumn 395, Issue 1, 2009, Pages 100-107

  Lu, Xiaojun ^a   DeFelippis, Michael R ^a   Huang, Lihua ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

Antigen antibody interaction; Epitope mapping; Linear epitopes; Monoclonal antibody; MS

Indexed keywords

EXTRACTION; MAPPING; MASS SPECTROMETRY; MONOCLONAL ANTIBODIES; PEPTIDES; SILVER COMPOUNDS;

ANTIGEN-ANTIBODY INTERACTION; EPITOPE MAPPING; LINEAR EPITOPES; MONOCLONAL ANTIBODIES (MABS); NATIVE MASS SPECTROMETRIES; PROTEOLYTIC ENZYME; SPECTROMETRIC MEASUREMENTS; THERAPEUTIC AGENTS;

EPITOPES;

AMYLOID BETA PROTEIN[1-40]; EPITOPE; IMMUNOGLOBULIN F(AB) FRAGMENT; LYSINE; MONOCLONAL ANTIBODY;

ANTIBODY SPECIFICITY; ANTIGEN BINDING; ARTICLE; CONTROLLED STUDY; DATA ANALYSIS; EPITOPE MAPPING; EXTRACTION; MASS SPECTROMETRY; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN DEGRADATION;

AMINO ACID SEQUENCE; AMYLOID BETA-PEPTIDES; ANALYTIC SAMPLE PREPARATION METHODS; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGEN-ANTIBODY COMPLEX; EPITOPE MAPPING; IMMUNOGLOBULIN FAB FRAGMENTS; MICE; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PEPTIDE HYDROLASES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 70349145361     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2009.08.018     Document Type: Article

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