Acute toxicity study of a simian immunodeficiency virus-based lentiviral vector for retinal gene transfer in nonhuman primates

Human Gene Therapy

Volumn 20, Issue 9, 2009, Pages 943-954

  Ikeda, Yasuhiro ^a   Yonemitsu, Yoshikazu ^b   Miyazaki, Masanori ^a   Kohno, Ri Ichiro ^a   Murakami, Yusuke ^a   Murata, Toshinori ^c   Goto, Yoshinobu ^d   Tabata, Toshiaki ^e   Ueda, Yasuji ^b   Ono, Fumiko ^f   Suzuki, Toshimichi ^f   Ageyama, Naohide ^g   Terao, Keiji ^g   Hasegawa, Mamoru ^e   Sueishi, Katsuo ^a   Ishibashi, Tatsuro ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b CHIBA UNIVERSITY   (Japan)

^c SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d INTERNATIONAL UNIVERSITY OF HEALTH AND WELFARE   (Japan)

^e University of Tokyo   (Japan)

^f The Corporation for Production and Research of Laboratory Primates   (Japan)

^g NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

LENTIVIRUS VECTOR; PIGMENT EPITHELIUM DERIVED FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMICROSCOPY; CARCINOGENESIS; CERCOPITHECIDAE; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; ELECTRORETINOGRAPHY; EYE TOXICITY; FLUORESCENCE ANGIOGRAPHY; GENE TRANSFER; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTRAOCULAR PRESSURE; MACACA; NONHUMAN; PIGMENT EPITHELIUM; SIMIAN IMMUNODEFICIENCY VIRUS;

ANIMALS; CELL LINE; DRUG EVALUATION, PRECLINICAL; ELECTRORETINOGRAPHY; EYE PROTEINS; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HUMANS; MACACA FASCICULARIS; MODELS, ANIMAL; NERVE GROWTH FACTORS; RETINA; SERPINS; SIMIAN IMMUNODEFICIENCY VIRUS; TRANSDUCTION, GENETIC; TRANSGENES; TREATMENT OUTCOME;

ANIMALIA; CERCOPITHECUS AETHIOPS; PRIMATES; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 70349131216     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.2009.048     Document Type: Article

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