Nonlinear model predictive control for the polymorphic transformation of l-glutamic acid crystals

AIChE Journal

Volumn 55, Issue 10, 2009, Pages 2631-2645

  Hermanto, Martin Wijaya ^a   Chiu, Min Sen ^a   Braatz, Richard D ^b  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Extended predictive self adaptive control; Nonlinear model predictive control; Pharmaceutical crystallization; Polymorphism; Unscented Kalman filter

Indexed keywords

BATCH TIME; CONCENTRATION CONTROL; CONTROL OBJECTIVES; CRYSTAL FORMS; CRYSTALLIZATION PROCESS; DISSOLUTION RATES; EXTENDED PREDICTIVE SELF-ADAPTIVE CONTROL; L-GLUTAMIC ACIDS; MATRIX; MODEL MISMATCH; NON-LINEARITY; NONLINEAR MODEL PREDICTIVE CONTROL; OPTIMAL VALUES; PARAMETER PERTURBATION; PHARMACEUTICAL CRYSTALLIZATION; PHARMACEUTICAL INDUSTRY; POLYMORPHIC TRANSFORMATION; PRODUCT QUALITY; SIMULATION STUDIES; SPECIALITY CHEMICALS; STATE VARIABLES; UNSCENTED KALMAN FILTER;

ADAPTIVE CONTROL SYSTEMS; CRYSTALLIZATION; DISSOLUTION; DRUG PRODUCTS PLANTS; KALMAN FILTERS; LINEARIZATION; NONLINEAR FILTERING; POLYMORPHISM; PREDICTIVE CONTROL SYSTEMS; ROBUSTNESS (CONTROL SYSTEMS);

MODEL PREDICTIVE CONTROL;

EID: 70349118274     PISSN: 00011541     EISSN: 15475905     Source Type: Journal    
DOI: 10.1002/aic.11879     Document Type: Article

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