Amphipathic β-strand mimics as potential membrane disruptive antibiotics

Journal of Organic Chemistry

Volumn 74, Issue 16, 2009, Pages 5953-5960

  Watson, Jessica L ^a   Gillies, Elizabeth R ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHIPATHIC; AMPHIPHILICITY; ANTIMICROBIAL PEPTIDE; BACTERIAL CELLS; BACTERIAL STRAINS; CHEMICAL EQUATIONS; FLUORESCENT DYES; L-AMINO ACIDS; MAMMALIAN CELLS; MAMMALIAN MEMBRANES; PHOSPHOLIPID VESICLES; PROTEOLYTIC DEGRADATION; SIDE CHAINS; STRUCTURAL FEATURE;

AMINATION; AMINO ACIDS; ANTIBIOTICS; BACTERIOLOGY; LIPOSOMES; MAMMALS; MOLECULES; OLIGOMERS; ORGANIC ACIDS; PEPTIDES; PHOSPHOLIPIDS; POLYPEPTIDES;

AMINES;

ALPHA AMINO ACID; AMPHOPHILE; CATION; DEXTRO AMINO ACID; LYSINE; OLIGOMER; VALINE; ANTIINFECTIVE AGENT; ANTIMICROBIAL CATIONIC PEPTIDE; ARTIFICIAL MEMBRANE; BIOMIMETIC MATERIAL; FLUORESCENT DYE; PYRIDINIUM DERIVATIVE; SULFONIC ACID DERIVATIVE;

ARTICLE; BACTERIAL MEMBRANE; BETA SHEET; CELL MEMBRANE; DILUTION; DIMERIZATION; HYDROPHOBICITY; MEMBRANE DAMAGE; PHOSPHOLIPID VESICLE; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS; ANIMAL; ARTIFICIAL MEMBRANE; CHEMISTRY; DRUG EFFECTS; PROTEIN SECONDARY STRUCTURE;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BIOMIMETIC MATERIALS; CELL MEMBRANE; FLUORESCENT DYES; MEMBRANES, ARTIFICIAL; PROTEIN STRUCTURE, SECONDARY; PYRIDINIUM COMPOUNDS; SULFONIC ACIDS;

EID: 70349117723     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo900933r     Document Type: Article

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