Quaternary alkaloid, pseudocoptisine isolated from tubers of Corydalis turtschaninovi inhibits LPS-induced nitric oxide, PGE2, and pro-inflammatory cytokines production via the down-regulation of NF-κB in RAW 264.7 murine macrophage cells

International Immunopharmacology

Volumn 9, Issue 11, 2009, Pages 1323-1331

  Yun, Kyung Jin ^a   Shin, Ji Sun ^a   Choi, Jung Hye ^a   Back, Nam In ^a   Chung, Hae Gon ^b   Lee, Kyung Tae ^a  

^a Kyung Hee University   (South Korea)

^b GangHwa Agricultural R and D Center   (South Korea)

Author keywords

Corydalis turtschaninovii; Cyclooxygenase 2; Inducible nitric oxide; Nuclear factor kappa B; Pseudocoptisine

Indexed keywords

ALKALOID; COPTISINE; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PROSTAGLANDIN E2; PSEUDOCOPTISINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORYDALIS; DNA BINDING; DOWN REGULATION; MACROPHAGE; MOUSE; NONHUMAN; PLANT TUBER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ANIMALS; BENZYLISOQUINOLINES; CELL LINE; CELL SURVIVAL; CORYDALIS; CYCLOOXYGENASE 2; CYTOKINES; DINOPROSTONE; DOWN-REGULATION; I-KAPPA B PROTEINS; INFLAMMATION MEDIATORS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NF-KAPPA B; NITRIC OXIDE; PHOSPHORYLATION; PLANT TUBERS; QUATERNARY AMMONIUM COMPOUNDS;

EID: 70249145062     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2009.08.001     Document Type: Article

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