Validation of a new yeast-based reporter assay consisting of human estrogen receptors α/β and coactivator SRC-1: Application for detection of estrogenic activity in environmental samples

Environmental Toxicology

Volumn 24, Issue 5, 2009, Pages 513-521

  Chu, Wai Ling ^a   Shiizaki, Kazuhiro ^a   Kawanishi, Masanobu ^a   Kondo, Mami ^a   Yagi, Takashi ^a  

^a Osaka Prefecture University   (Japan)

Author keywords

E2; Endocrine disruptor; ER ; ER ; Estrogen nuclear receptor; SRC 1; Yamato river; Yeast bioassay

Indexed keywords

E2; ENDOCRINE DISRUPTOR; ESTROGEN NUCLEAR RECEPTOR; SRC-1; YAMATO RIVER; YEAST BIOASSAY;

BIOASSAY; ENDOCRINOLOGY; HORMONES; LIGANDS; PHENOLS; YEAST;

RIVERS;

4,4' ISOPROPYLIDENEDIPHENOL; BETA GALACTOSIDASE; DIETHYLSTILBESTROL; EMODIN; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; GENISTEIN; PHYTOESTROGEN; PLASMID VECTOR; RIVER WATER; STEROID RECEPTOR COACTIVATOR 1;

BIOASSAY; DOSE-RESPONSE RELATIONSHIP; DRUG PRESCRIBING; ENDOCRINE DISRUPTOR; ENDOCRINE SYSTEM; ENDOGENOUS GROWTH; ESTROGENIC COMPOUND; GENE; HORMONE; LIGAND; PHENOLIC COMPOUND; PHYSIOLOGICAL RESPONSE; PLASMID; SAMPLING; YEAST;

ARTICLE; BIOASSAY; CONTROLLED STUDY; ESTROGEN ACTIVITY; GENE EXPRESSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; REPORTER GENE; SACCHAROMYCES CEREVISIAE; WATER POLLUTANT; WATER SAMPLING; YEAST;

BIOLOGICAL ASSAY; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL MONITORING; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; ESTROGENS; GENES, REPORTER; HISTONE ACETYLTRANSFERASES; LIGANDS; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; WATER POLLUTANTS, CHEMICAL;

SACCHAROMYCES CEREVISIAE;

EID: 70249136120     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.20473     Document Type: Article

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