Inhibition of inducible nitric oxide synthesis by Cimicifuga racemosa (Actaea racemosa, black cohosh) extracts in LPS-stimulated RAW 264.7 macrophages

Journal of Pharmacy and Pharmacology

Volumn 61, Issue 8, 2009, Pages 1089-1096

  Schmid, Diethart ^a   Gruber, Miriam ^a   Woehs, Florian ^a   Prinz, Sonja ^b   Etzlstorfer, Barbara ^a   Prucker, Christina ^a   Fuzzati, Nicola ^c   Kopp, Brigitte ^b   Moeslinger, Thomas ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF VIENNA   (Austria)

^c INDENA S P A   (Italy)

Author keywords

Actaea racemosa; Cimicifuga racemosa; Inducible nitric oxide synthase; Inflammation; Murine macrophages; Nuclear factor B; Ranunculaceae

Indexed keywords

23 EPI 26 DEOXYACTEIN; BETA INTERFERON; CAFFEIC ACID; CARBOXYLIC ACID DERIVATIVE; CIMICIFUGA RACEMOSA EXTRACT; CIMICIFUGIC ACID; FERULIC ACID; FUKINOLIC ACID; GLYCOSIDE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERFERON REGULATORY FACTOR 1; ISOFERULIC ACID; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC OXIDE; NITRITE; TRANSCRIPTION FACTOR RELA; TRITERPENE DERIVATIVE; UNCLASSIFIED DRUG; CARBOXYLIC ACID; PLANT EXTRACT; TRITERPENE;

ANIMAL CELL; ARTICLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOBLOTTING; MACROPHAGE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHIZOME; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CHEMISTRY; CIMICIFUGA; DOSE RESPONSE; DRUG ANTAGONISM; GENE EXPRESSION REGULATION; ISOLATION AND PURIFICATION; METABOLISM; PLANT ROOT; RABBIT; TRADITIONAL MEDICINE;

ANIMALS; CARBOXYLIC ACIDS; CELLS, CULTURED; CIMICIFUGA; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLYCOSIDES; LIPOPOLYSACCHARIDES; MACROPHAGES; MEDICINE, TRADITIONAL; MICE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PLANT EXTRACTS; PLANT ROOTS; RABBITS; RNA, MESSENGER; TRITERPENES;

EID: 70249087332     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp/61.08.0013     Document Type: Article

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