Molecular mechanisms underlying the cholesterol-lowering effect of Ginkgo biloba extract in hepatocytes: A comparative study with lovastatin

Acta Pharmacologica Sinica

Volumn 30, Issue 9, 2009, Pages 1262-1275

  Xie, Zuo Quan ^a,b   Liang, Gai ^c   Zhang, Lu ^a,b   Wang, Qi ^b   Qu, Yi ^b   Gao, Yang ^b   Lin, Li Bo ^b   Ye, Sai ^b   Zhang, Ji ^a   Wang, Hui ^c   Zhao, Guo Ping ^b,d   Zhang, Qing Hua ^a,b,d  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b Shanghai Biochip Co Ltd   (China)

^c WUHAN UNIVERSITY   (China)

^d Shanghai Ministry Key Laboratory of Disease and Health Genomics   (China)

Author keywords

Cholesterol; Ginkgo biloba extract; HMG CoA reductase; Influx; Lovastatin; Microarray

Indexed keywords

CHOLESTEROL; COMPLEMENTARY DNA; GINKGO BILOBA EXTRACT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYPOCHOLESTEROLEMIC AGENT; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 10; LYMPHOCYTE ANTIGEN; MEVINOLIN; PROTEIN INSIG2; UNCLASSIFIED DRUG;

ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL METABOLISM; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; HUMAN; HUMAN CELL; LIVER CELL; NUCLEOTIDE SEQUENCE; TRANSCRIPTOMICS; UNINDEXED SEQUENCE;

ANIMALS; ANTICHOLESTEREMIC AGENTS; CHOLESTEROL; GENE EXPRESSION; GINKGO BILOBA; HEPATOCYTES; HUMANS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; LOVASTATIN; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PLANT EXTRACTS; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR CELLS, CULTURED;

EID: 70249084499     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2009.126     Document Type: Article

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