The two-domain LysX protein of Mycobacterium tuberculosis is required for production of lysinylated phosphatidylglycerol and resistance to cationic antimicrobial peptides

PLoS Pathogens

Volumn 5, Issue 7, 2009, Pages

  Maloney, Erin ^a   Stankowska, Dorota ^a   Zhang, Jian ^b   Fol, Marek ^a,d   Cheng, Qi Jian ^c   Lun, Shichun ^c   Bishai, William R ^c   Rajagopalan, Malini ^a   Chatterjee, Delphi ^b   Madiraju, Murty V ^a  

^a UNIVERSITY OF TEXAS HEALTH CENTER   (United States)

^b Department of Environmental and Radiological Health Sciences   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF LODZ   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID TRANSFER RNA LIGASE; LYSOSOME ASSOCIATED MEMBRANE PROTEIN; PHOSPHATIDYLGLYCEROL; POLYPEPTIDE ANTIBIOTIC AGENT; TRANSFERASE; ANTIMICROBIAL CATIONIC PEPTIDE; BACTERIAL PROTEIN; CYTOKINE; LAMP1 PROTEIN, HUMAN; LYSINE; LYSOPHOSPHOLIPID; PHOSPHOLIPID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CONTROLLED STUDY; GENE ACTIVITY; GENE EXPRESSION; GENE FUNCTION; HUMAN; LYSOSOME MEMBRANE; LYSX BACTERIAL GENE; MACROPHAGE; MEMBRANE POTENTIAL; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHENOTYPE; PROTEIN DOMAIN; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL MEMBRANE POTENTIAL; CHEMISTRY; DRUG EFFECT; FEMALE; GENETICS; GUINEA PIG; LUNG; MASS SPECTROMETRY; METABOLISM; MUTATION; PATHOLOGY; PHAGOSOME; PROTEIN TERTIARY STRUCTURE;

CAVIA; MYCOBACTERIUM TUBERCULOSIS;

ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIAL PROTEINS; CYTOKINES; DRUG RESISTANCE, BACTERIAL; FEMALE; GUINEA PIGS; HUMANS; LUNG; LYSINE; LYSOPHOSPHOLIPIDS; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; MACROPHAGES; MEMBRANE POTENTIALS; MICE; MICE, INBRED C57BL; MUTATION; MYCOBACTERIUM TUBERCULOSIS; PHAGOSOMES; PHENOTYPE; PHOSPHATIDYLGLYCEROLS; PHOSPHOLIPIDS; PROTEIN STRUCTURE, TERTIARY; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 70049106239     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000534     Document Type: Article

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