Accelerated detection of Mycobacterium tuberculosis genes essential for bacterial survival in guinea pigs, compared with mice

Journal of Infectious Diseases

Volumn 195, Issue 11, 2007, Pages 1634-1642

  Jain, Sanjay K ^a   Hernandez Abanto, S Moises ^a   Cheng, Qi Jian ^a   Singh, Prabhpreet ^a   Ly, Lan H ^b   Klinkenberg, Lee G ^a   Morrison, Norman E ^a   Converse, Paul J ^a   Nuermberger, Eric ^a   Grosset, Jacques ^a   McMurray, David N ^b   Karakousis, Petros C ^a   Lamichhane, Gyanu ^a   Bishai, William R ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AEROSOL; ANIMAL EXPERIMENT; ARTICLE; ASSAY; BACTERIAL GENE; BACTERIAL INFECTION; BACTERIAL SURVIVAL; BACTERIUM DETECTION; BACTERIUM MUTANT; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; GENETIC IDENTIFICATION; GENOTYPE; GUINEA PIG; HOLLOW FIBER; LUNG; MICROBIAL ATTENUATION; MODEL; MOUSE; MUTATIONAL ANALYSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

EID: 34249062341     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/517526     Document Type: Article

References (25)

1. World Health Organization. Global tuberculosis control - surveillance, planning, financing. Available at: http://www.who.int/tb/publications/ global_report/en/. Accessed 1 November 2006.
2. Hingley-Wilson SM, Sambandamurthy VK, Jacobs WR Jr. Survival perspectives from the world's most successful pathogen, Mycobacterium tuberculosis. Nat Immunol 2003; 4:949-55.
3. Nuermberger E, Bishai WR, Grosset JH. Latent tuberculosis infection. Semin Respir Crit Care Med 2004; 25:317-36.
4. Sassetti CM, Boyd DH, Rubin EJ. Genes required for mycobacterial growth defined by high density mutagenesis. Mol Microbiol 2003; 48:77-84.
5. Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proc Natl Acad Sci USA 2003; 100:12989-94.
6. Lamichhane G, Tyagi S, Bishai WR. Designer arrays for defined mutant analysis to detect genes essential for survival of Mycobacterium tuberculosis in mouse lungs. Infect Immun 2005; 73:2533-40.
7. Turner OC, Basaraba RJ, Orme IM. Immunopathogenesis of pulmonary granulomas in the guinea pig after infection with Mycobacterium tuberculosis. Infect Immun 2003; 71:864-71.
8. Lamichhane G, Zignol M, Blades NJ, et al. A postgenomic method for predicting essential genes at subsaturation levels of mutagenesis: application to Mycobacterium tuberculosis. Proc Natl Acad Sci USA 2003; 100:7213-8.
9. Rubin EJ, Akerley BJ, Novik VN, Lampe DJ, Husson RN, Mekalanos JJ. In vivo transposition of mariner-based elements in enteric bacteria and mycobacteria. Proc Natl Acad Sci USA 1999; 96:1645-50.
10. Chen P, Ruiz RE, Li Q, Silver RF, Bishai WR. Construction and characterization of a Mycobacterium tuberculosis mutant lacking the alternate sigma factor gene, sigF. Infect Immun 2000; 68:5575-80.
11. Wiegeshaus EH, McMurray DN, Grover AA, Harding GE, Smith DW. Host-parasite relationships in experimental airborne tuberculosis. 3. Relevance of microbial enumeration to acquired resistance in guinea pigs. Am Rev Respir Dis 1970; 102:422-9.
12. Larsen M. Some common methods in mycobacterial genetics. In: Jacobs W Jr, Hatfull G, eds. Molecular genetics of Mycobacteria. Washington, DC: ASM Press, 2000:316-7.
13. Karakousis PC, Yoshimatsu T, Lamichhane G, et al. Dormancy phenotype displayed by extracellular Mycobacterium tuberculosis within artificial granulomas in mice. J Exp Med 2004; 200:647-57.
14. Cole ST. TubercuList. WWW server v3.1. Available at: http://genolist. pasteur.fr/TubercuList/. Accessed 1 November 2006.
15. The Institute for Genomic Research. Mycobacterium tuberculosis CDC1551 genome. Available at: http://cmr.tigr.org/tigr-scripts/CMR/GenomePage. cgi?org_search=&org=gmt. Accessed 1 November 2006.
16. Kaushal D, Schroeder BG, Tyagi S, et al. Reduced immunopathology and mortality despite tissue persistence in a Mycobacterium tuberculosis mutant lacking alternative sigma factor, SigH. Proc Natl Acad Sci USA 2002; 99:8330-5.
17. Karls RK, Guarner J, McMurray DN, Birkness KA, Quinn FD. Examination of Mycobacterium tuberculosis sigma factor mutants using low-dose aerosol infection of guinea pigs suggests a role for SigC in pathogenesis. Microbiology 2006; 152:1591-600.
18. Sun R, Converse PJ, Ko C, Tyagi S, Morrison NE, Bishai WR. Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set. Mol Microbiol 2004; 52:25-38.
19. Bishai WR, Dannenberg AM Jr, Parrish N, et al. Virulence of Mycobacterium tuberculosis CDC1551 and H37Rv in rabbits evaluated by Lurie's pulmonary tubercle count method. Infect Immun 1999; 67:4931-4.
20. Murphy HN, Stewart GR, Mischenko VV, et al. The OtsAB pathway is essential for trehalose biosynthesis in Mycobacterium tuberculosis. J Biol Chem 2005; 280:14524-9.
21. Betts JC, Lukey PT, Robb LC, McAdam RA, Duncan K. Evaluation of a nutrient starvation model of Mycobacterium tuberculosis persistence by gene and protein expression profiling. Mol Microbiol 2002; 43:717-31.
22. Schnappinger D, Ehrt S, Voskuil MI, et al. Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: insights into the phagosomal environment. J Exp Med 2003; 198:693-704.
23. Manganelli R, Voskuil MI, Schoolnik GK, Dubnau E, Gomez M, Smith I. Role of the extracytoplasmic-function sigma factor sigma(H) in Mycobacterium tuberculosis global gene expression. Mol Microbiol 2002; 45:365-74.
24. Muttucumaru DG, Roberts G, Hinds J, Stabler RA, Parish T. Gene expression profile of Mycobacterium tuberculosis in a non-replicating state. Tuberculosis (Edinb) 2004; 84:239-46.
25. Sirakova TD, Dubey VS, Cynamon MH, Kolattukudy PE. Attenuation of Mycobacterium tuberculosis by disruption of a mas-like gene or a chalcone synthase-like gene, which causes deficiency in dimycocerosyl phthiocerol synthesis. J Bacteriol 2003; 185:2999-3008.