Gln-222 in transmembrane domain 4 and Gln-526 in transmembrane domain 9 are critical for substrate recognition in the yeast high affinity glutathione transporter, Hgt1p

Journal of Biological Chemistry

Volumn 284, Issue 35, 2009, Pages 23872-23884

  Kaur, Jaspreet ^a   Bachhawat, Anand K ^a  

^a INSTITUTE OF MICROBIAL TECHNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACES; CHARGED RESIDUES; CONSERVED REGIONS; DIFFERENT SUBSTRATES; DIFFERENTIAL CONTRIBUTION; FUNCTIONAL ACTIVITIES; FUNCTIONAL CHARACTERIZATION; GLUTATHIONES; HIGH AFFINITY; INTRACELLULAR LOOP; KINETIC ANALYSIS; OLIGOPEPTIDES; POLAR RESIDUES; PROLINE-RICH MOTIF; PROTEIN EXPRESSION LEVELS; STRUCTURAL FEATURE; SUBSTRATE RECOGNITION; SUBSTRATE SPECIFICITY; TRANS-MEMBRANE DOMAINS; TRANSPORT ACTIVITY; WILD TYPES; YEAST SACCHAROMYCES CEREVISIAE;

ACTIVATION ANALYSIS; BIOLOGICAL MEMBRANES; SUBSTRATES; YEAST;

CELL MEMBRANES;

ALANINE; AMINO ACID; ARGININE; ASPARAGINE; CARRIER PROTEIN; CELL EXTRACT; GLUTAMIC ACID; GLUTAMINE; GLUTATHIONE; GLUTATHIONE TRANSPORTER; LYSINE; PROLINE; PROTEIN HGT1P; UNCLASSIFIED DRUG;

ARTICLE; CELL SURFACE; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME SPECIFICITY; FUNGAL STRAIN; IMMUNOBLOTTING; KINETICS; MUTANT; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN STRUCTURE; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; WILD TYPE;

AMINO ACID SEQUENCE; GLUTATHIONE; KINETICS; MOLECULAR SEQUENCE DATA; MONOSACCHARIDE TRANSPORT PROTEINS; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY;

SACCHAROMYCES CEREVISIAE;

EID: 69949162869     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.029728     Document Type: Article

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