The structures of human glutathione transferase P1-1 in complex with glutathione and various inhibitors at high resolution

Journal of Molecular Biology

Volumn 274, Issue 1, 1997, Pages 84-100

  Oakley, Aaron J ^a   Bello, Mario Lo ^b   Battistoni, Andrea ^b   Ricci, Giorgio ^b   Rossjohn, Jamie ^a   Villar, Hugo O ^c   Parker, Michael W ^a  

^a ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c Terrapin Technologies Inc   (United States)

Author keywords

Detoxification; Enzyme mechanism; Glutathione S transferases; Inhibitor complexes; X ray crystallography

Indexed keywords

ENZYME INHIBITOR; GLUTATHIONE; GLUTATHIONE TRANSFERASE; GLYCINE DERIVATIVE; HYDROXYL GROUP; PHENYL GROUP; S HEXYLGLUTATHIONE; THIOL GROUP; WATER;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME INHIBITOR COMPLEX; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL;

EID: 0141648082     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1997.1364     Document Type: Article

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