Molecular basis of the acceleration of the GDP-GTP exchange of human Ras homolog enriched in brain by human translationally controlled tumor protein

Journal of Biological Chemistry

Volumn 284, Issue 35, 2009, Pages 23754-23764

  Dong, Xianchi ^a,b   Yang, Bei ^a,b   Li, Yingjie ^a,b   Zhong, Chen ^a   Ding, Jianping ^a  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ANALYSIS; BRIDGING INTERACTIONS; CONFORMATIONAL CHANGE; GUANINE NUCLEOTIDE EXCHANGE FACTORS; IN-VITRO; IN-VIVO; MOLECULAR BASIS; MOLECULAR DYNAMICS SIMULATIONS; MOLECULAR MECHANISM; SITE DIRECTED MUTAGENESIS; STRUCTURE MODELS; UNDERLYING MECHANISM;

CELL MEMBRANES; MOLECULAR DYNAMICS; PROTEINS; TUMORS;

CRYSTAL STRUCTURE;

GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATASE; MAMMALIAN TARGET OF RAPAMYCIN; MUTANT PROTEIN; RHEB PROTEIN; TRANSLATIONALLY CONTROLLED TUMOR PROTEIN; TUMOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL ANALYSIS; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS;

BINDING SITES; CELL LINE; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; HUMANS; MOLECULAR CONFORMATION; MONOMERIC GTP-BINDING PROTEINS; NEUROPEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TUMOR MARKERS, BIOLOGICAL;

EID: 69949143367     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.012823     Document Type: Article

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