메뉴 건너뛰기




Volumn 68, Issue 3, 2009, Pages 395-401

Influence of ABCB1 gene polymorphisms on the pharmacokinetics of verapamil among healthy Chinese Han ethnic subjects

Author keywords

ABCB1; Pharmacokinetics; SNP; Verapamil

Indexed keywords

MULTIDRUG RESISTANCE PROTEIN 1; VERAPAMIL;

EID: 69949112838     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2009.03467.x     Document Type: Article
Times cited : (12)

References (49)
  • 1
    • 0022619907 scopus 로고
    • The role of calcium channel blockers in the treatment of hypertension
    • Halperin AK, Cubeddu LX. The role of calcium channel blockers in the treatment of hypertension. Am Heart J 1986 111 : 363 382.
    • (1986) Am Heart J , vol.111 , pp. 363-382
    • Halperin, A.K.1    Cubeddu, L.X.2
  • 3
    • 33750626722 scopus 로고    scopus 로고
    • The effect of gender on the pharmacokinetics of verapamil and norverapamil in humans
    • Dadashzadeh S, Javadian B, Sadeghian S. The effect of gender on the pharmacokinetics of verapamil and norverapamil in humans. Biopharm Drug Dispos 2006 27 : 329 334.
    • (2006) Biopharm Drug Dispos , vol.27 , pp. 329-334
    • Dadashzadeh, S.1    Javadian, B.2    Sadeghian, S.3
  • 4
    • 41049105457 scopus 로고    scopus 로고
    • Drug interaction between oral atorvastatin and verapamil in healthy subjects: Effects of atorvastatin on the pharmacokinetics of verapamil and norverapamil
    • Choi DH, Shin WG, Choi JS. Drug interaction between oral atorvastatin and verapamil in healthy subjects: effects of atorvastatin on the pharmacokinetics of verapamil and norverapamil. Eur J Clin Pharmacol 2008 64 : 445 449.
    • (2008) Eur J Clin Pharmacol , vol.64 , pp. 445-449
    • Choi, D.H.1    Shin, W.G.2    Choi, J.S.3
  • 5
    • 10044220716 scopus 로고    scopus 로고
    • The effect of quercetin on the pharmacokinetics of verapamil and its major metabolite, norverapamil in rabbits
    • Choi JS, Han HK. The effect of quercetin on the pharmacokinetics of verapamil and its major metabolite, norverapamil in rabbits. J Pharm Pharmacol 2004 56 : 1537 1542.
    • (2004) J Pharm Pharmacol , vol.56 , pp. 1537-1542
    • Choi, J.S.1    Han, H.K.2
  • 6
    • 0034467564 scopus 로고    scopus 로고
    • Effect of grapefruit juice on pharmacokinetics and pharmacodynamics of verapamil enantiomers in healthy volunteers
    • Ho PC, Ghose K, Saville D, Wanwimolruk S. Effect of grapefruit juice on pharmacokinetics and pharmacodynamics of verapamil enantiomers in healthy volunteers. Eur J Clin Pharmacol 2000 56 : 693 698.
    • (2000) Eur J Clin Pharmacol , vol.56 , pp. 693-698
    • Ho, P.C.1    Ghose, K.2    Saville, D.3    Wanwimolruk, S.4
  • 7
    • 0034936354 scopus 로고    scopus 로고
    • ABC drug transporters: Hereditary polymorphisms and pharmacological impact in MDR1, MRP1 and MRP2
    • Kerb R, Hoffmeyer S, Brinkmann U. ABC drug transporters: hereditary polymorphisms and pharmacological impact in MDR1, MRP1 and MRP2. Pharmacogenomics 2001 2 : 51 64.
    • (2001) Pharmacogenomics , vol.2 , pp. 51-64
    • Kerb, R.1    Hoffmeyer, S.2    Brinkmann, U.3
  • 8
    • 0013095102 scopus 로고    scopus 로고
    • MDR1 genotype-related pharmacokinetics and pharmacodynamics
    • Sakaeda T, Nakamura T, Okumura K. MDR1 genotype-related pharmacokinetics and pharmacodynamics. Biol Pharm Bull 2002 25 : 1391 1400.
    • (2002) Biol Pharm Bull , vol.25 , pp. 1391-1400
    • Sakaeda, T.1    Nakamura, T.2    Okumura, K.3
  • 9
    • 0141888537 scopus 로고    scopus 로고
    • The role of ABC transporters in clinical practice
    • Leonard GD, Fojo T, Bates SE. The role of ABC transporters in clinical practice. Oncologist 2003 8 : 411 424.
    • (2003) Oncologist , vol.8 , pp. 411-424
    • Leonard, G.D.1    Fojo, T.2    Bates, S.E.3
  • 10
    • 0026654583 scopus 로고
    • Stereoisomers of calcium antagonists which differ markedly in their potencies as calcium blockers are equally effective in modulating drug transport by p-glycoprotein. Biochemistry and
    • Hollt V, Kouba M, Dietel M, Vogt G. Stereoisomers of calcium antagonists which differ markedly in their potencies as calcium blockers are equally effective in modulating drug transport by p-glycoprotein. Biochemistry and. Pharmacology 1992 40 : 2601 2608.
    • (1992) Pharmacology , vol.40 , pp. 2601-2608
    • Hollt, V.1    Kouba, M.2    Dietel, M.3    Vogt, G.4
  • 11
    • 0035098868 scopus 로고    scopus 로고
    • A comprehensive account on the role of efflux transporters in the gastrointestinal absorption of 13 commonly used substrate drugs in humans
    • Chiou WL, Chung SM, Wu TC, Ma C. A comprehensive account on the role of efflux transporters in the gastrointestinal absorption of 13 commonly used substrate drugs in humans. Int J Clin Pharmacol Ther 2001 39 : 93 101.
    • (2001) Int J Clin Pharmacol Ther , vol.39 , pp. 93-101
    • Chiou, W.L.1    Chung, S.M.2    Wu, T.C.3    Ma, C.4
  • 12
    • 0037406370 scopus 로고    scopus 로고
    • Differential effect of acute hepatic failure on in vivo and in vitro P-glycoprotein functions in the intestine
    • Yumoto R, Murakami T, Takano M. Differential effect of acute hepatic failure on in vivo and in vitro P-glycoprotein functions in the intestine. Pharm Res 2003 20 : 765 771.
    • (2003) Pharm Res , vol.20 , pp. 765-771
    • Yumoto, R.1    Murakami, T.2    Takano, M.3
  • 13
    • 33644647219 scopus 로고    scopus 로고
    • Genetic polymorphisms of drug-metabolising enzymes and drug transporters in the chemotherapeutic treatment of cancer
    • DOI 10.2165/00003088-200645030-00003
    • Bosch TM, Meijerman I, Beijnen JH, Schellens JH. Genetic polymorphisms of drug-metabolizing enzymes and drug transporters in the chemotherapeutic treatment of cancer. Clin Pharmacokinet 2006 45 : 253 285. (Pubitemid 43327492)
    • (2006) Clinical Pharmacokinetics , vol.45 , Issue.3 , pp. 253-285
    • Bosch, T.M.1    Meijerman, I.2    Beijnen, J.H.3    Schellens, J.H.M.4
  • 15
    • 0036904332 scopus 로고    scopus 로고
    • MDR1 genotypes do not influence the absorption of a single oral dose of 1 mg digoxin in healthy white males
    • Gerloff T, Schaefer M, Johne A, Oselin K, Meisel C, Cascorbi I, Roots I. MDR1 genotypes do not influence the absorption of a single oral dose of 1 mg digoxin in healthy white males. Br J Clin Pharmacol 2002 54 : 610 616.
    • (2002) Br J Clin Pharmacol , vol.54 , pp. 610-616
    • Gerloff, T.1    Schaefer, M.2    Johne, A.3    Oselin, K.4    Meisel, C.5    Cascorbi, I.6    Roots, I.7
  • 20
    • 0017658101 scopus 로고
    • Bioavailability of digoxin: Some pitfalls and problems
    • Keller F, Rietbrock N. Bioavailability of digoxin: some pitfalls and problems. Int J Clin Pharmacol Biopharm 1977 15 : 549 556.
    • (1977) Int J Clin Pharmacol Biopharm , vol.15 , pp. 549-556
    • Keller, F.1    Rietbrock, N.2
  • 23
    • 0036803396 scopus 로고    scopus 로고
    • Significant genetic linkage of MDR1 polymorphisms at positions 3435 and 2677: Functional relevance to pharmacokinetics of digoxin
    • Horinouchi M, Sakaeda T, Nakamura T, Morita Y, Tamura T, Aoyama N, Kasuga M, Okumura K. Significant genetic linkage of MDR1 polymorphisms at positions 3435 and 2677: functional relevance to pharmacokinetics of digoxin. Pharm Res 2002 19 : 1581 1585.
    • (2002) Pharm Res , vol.19 , pp. 1581-1585
    • Horinouchi, M.1    Sakaeda, T.2    Nakamura, T.3    Morita, Y.4    Tamura, T.5    Aoyama, N.6    Kasuga, M.7    Okumura, K.8
  • 24
    • 0037330517 scopus 로고    scopus 로고
    • Genetic polymorphisms in MDR1 and CYP3A4 genes in Asians and the influence of MDR1 haplotypes on cyclosporin disposition in heart transplant recipients
    • Chowbay B, Cumaraswamy S, Cheung YB, Zhou Q, Lee EJ. Genetic polymorphisms in MDR1 and CYP3A4 genes in Asians and the influence of MDR1 haplotypes on cyclosporin disposition in heart transplant recipients. Pharmacogenetics 2003 13 : 89 95.
    • (2003) Pharmacogenetics , vol.13 , pp. 89-95
    • Chowbay, B.1    Cumaraswamy, S.2    Cheung, Y.B.3    Zhou, Q.4    Lee, E.J.5
  • 31
    • 33646196008 scopus 로고    scopus 로고
    • Frequency of common MDR1 gene variants in a Polish population
    • Kurzawski M, Pawlik A, Gornik W, Drozdzik M. Frequency of common MDR1 gene variants in a Polish population. Pharmacol Rep 2006 58 : 35 40.
    • (2006) Pharmacol Rep , vol.58 , pp. 35-40
    • Kurzawski, M.1    Pawlik, A.2    Gornik, W.3    Drozdzik, M.4
  • 32
    • 0033569516 scopus 로고    scopus 로고
    • Pharmacogenomics: Translating functional genomics into rational therapeutics
    • Evans WE, Relling MV. Pharmacogenomics: translating functional genomics into rational therapeutics. Science 1999 286 : 487 491.
    • (1999) Science , vol.286 , pp. 487-491
    • Evans, W.E.1    Relling, M.V.2
  • 34
    • 34047185923 scopus 로고    scopus 로고
    • Impact of ABCB1 (MDR1) gene polymorphism and P-glycoprotein inhibitors on digoxin serum concentration in congestive heart failure patients
    • Kurzawski M, Bartnicka L, Florczak M, Górnik W, Drozdzik M. Impact of ABCB1 (MDR1) gene polymorphism and P-glycoprotein inhibitors on digoxin serum concentration in congestive heart failure patients. Pharmacol Rep 2007 59 : 107 111. (Pubitemid 46522710)
    • (2007) Pharmacological Reports , vol.59 , Issue.1 , pp. 107-111
    • Kurzawski, M.1    Bartnicka, L.2    Florczak, M.3    Gornik, W.4    Drozdzik, M.5
  • 35
    • 0141765814 scopus 로고    scopus 로고
    • MDR1 haplotypes do not affect the steady-state pharmacokinetics of cyclosporine in renal transplant patients
    • Mai I, Störmer E, Goldammer M, Johne A, Krüger H, Budde K, Roots I. MDR1 haplotypes do not affect the steady-state pharmacokinetics of cyclosporine in renal transplant patients. J Clin Pharmacol 2003 43 : 1101 1107.
    • (2003) J Clin Pharmacol , vol.43 , pp. 1101-1107
    • Mai, I.1    Störmer, E.2    Goldammer, M.3    Johne, A.4    Krüger, H.5    Budde, K.6    Roots, I.7
  • 36
    • 9144253194 scopus 로고    scopus 로고
    • MDR1 haplotypes derived from exons 21 and 26 do not affect the steady-state pharmacokinetics of tacrolimus in renal transplant patients
    • Mai I, Perloff ES, Bauer S, Goldammer M, Johne A, Filler G, Budde K, Roots I. MDR1 haplotypes derived from exons 21 and 26 do not affect the steady-state pharmacokinetics of tacrolimus in renal transplant patients. Br J Clin Pharmacol 2004 58 : 548 553.
    • (2004) Br J Clin Pharmacol , vol.58 , pp. 548-553
    • Mai, I.1    Perloff, E.S.2    Bauer, S.3    Goldammer, M.4    Johne, A.5    Filler, G.6    Budde, K.7    Roots, I.8
  • 37
    • 33845401618 scopus 로고    scopus 로고
    • Effect of ABCB1 (MDR1) haplotypes derived from G2677T/C3435T on the pharmacokinetics of amlodipine in healthy subjects
    • Kim KA, Park PW, Park JY. Effect of ABCB1 (MDR1) haplotypes derived from G2677T/C3435T on the pharmacokinetics of amlodipine in healthy subjects. Br J Clin Pharmacol 2007 63 : 53 8.
    • (2007) Br J Clin Pharmacol , vol.63 , pp. 53-8
    • Kim, K.A.1    Park, P.W.2    Park, J.Y.3
  • 38
    • 0020281917 scopus 로고
    • The pharmacology of verapamil. IV. Kinetic and dynamic effects after single intravenous and oral doses
    • McAllister RG Jr., Kirsten EB. The pharmacology of verapamil. IV. Kinetic and dynamic effects after single intravenous and oral doses. Clin Pharmacol Ther 1982 31 : 418 426.
    • (1982) Clin Pharmacol Ther , vol.31 , pp. 418-426
    • McAllister, Jr.R.G.1    Kirsten, E.B.2
  • 40
    • 0026519088 scopus 로고
    • Influence of time of administration on verapamil pharmacokinetics
    • Hla KK, Latham AN, Henry JA. Influence of time of administration on verapamil pharmacokinetics. Clin Pharmacol Ther 1992 51 : 366 370.
    • (1992) Clin Pharmacol Ther , vol.51 , pp. 366-370
    • Hla, K.K.1    Latham, A.N.2    Henry, J.A.3
  • 42
    • 40749137458 scopus 로고    scopus 로고
    • Dietary salt dose not influence the disposition of verapamil enantiomers in relation to efflux transporter ABCB1 genetic polymorphism in healthy Korean subjects
    • Pan W, Ryu JY, Shon JH, Song IS, Liu KH, Sunwoo YE, Kang W, Shin JG. Dietary salt dose not influence the disposition of verapamil enantiomers in relation to efflux transporter ABCB1 genetic polymorphism in healthy Korean subjects. Xenobiotica 2008 38 : 422 434.
    • (2008) Xenobiotica , vol.38 , pp. 422-434
    • Pan, W.1    Ryu, J.Y.2    Shon, J.H.3    Song, I.S.4    Liu, K.H.5    Sunwoo, Y.E.6    Kang, W.7    Shin, J.G.8
  • 43
    • 0026099628 scopus 로고
    • Pharmacodynamic profile of verapamil in relation to absolute bioavailability: Investigations with a conventional and controlled release formulation
    • Harder S, Thurmann P, Siewert M, Blume H, Huber TH, Rietbrock N. Pharmacodynamic profile of verapamil in relation to absolute bioavailability: investigations with a conventional and controlled release formulation. J Cardiovasc Pharmacol 1991 17 : 207 212.
    • (1991) J Cardiovasc Pharmacol , vol.17 , pp. 207-212
    • Harder, S.1    Thurmann, P.2    Siewert, M.3    Blume, H.4    Huber, T.H.5    Rietbrock, N.6
  • 46
    • 0023925897 scopus 로고
    • D-verapamil and L-verapamil are equally effective in increasing vincristine accumulation in leukemic cells in vitro
    • Gruber A, Peterson C, Reizenstein P. D-verapamil and L-verapamil are equally effective in increasing vincristine accumulation in leukemic cells in vitro. Int J Cancer 1988 41 : 224 226.
    • (1988) Int J Cancer , vol.41 , pp. 224-226
    • Gruber, A.1    Peterson, C.2    Reizenstein, P.3
  • 47
    • 0025164886 scopus 로고
    • The activity of verapamil as a resistance modifier in vitro in drug resistant human tumor cell lines is not stereospecific
    • Plumb JA, Milroy R, Kaye SB. The activity of verapamil as a resistance modifier in vitro in drug resistant human tumor cell lines is not stereospecific. Biochem Pharmacol 1990 39 : 787 792.
    • (1990) Biochem Pharmacol , vol.39 , pp. 787-792
    • Plumb, J.A.1    Milroy, R.2    Kaye, S.B.3
  • 48
    • 0344102285 scopus 로고
    • The use of R-verapamil (R-VPM) is superior to racemic VPM in breaking multidrug resistance (MDR) of malignant cells
    • Abstract).
    • Keilhauer C, Emling F, Raschak M, Gries J, Schlick E. The use of R-verapamil (R-VPM) is superior to racemic VPM in breaking multidrug resistance (MDR) of malignant cells. Proc Am Assoc Cancer Res 1989 30 : 503 (Abstract).
    • (1989) Proc Am Assoc Cancer Res , vol.30 , pp. 503
    • Keilhauer, C.1    Emling, F.2    Raschak, M.3    Gries, J.4    Schlick, E.5
  • 49
    • 10044270854 scopus 로고    scopus 로고
    • Haplotype-oriented genetic analysis and functional assessment of promoter variants in the MDR1 (ABCB1) gene
    • Takane H, Kobayashi D, Hirota T, Kiqawa J, Terakawa N, Otsubo K, Ieiri I. Haplotype-oriented genetic analysis and functional assessment of promoter variants in the MDR1 (ABCB1) gene. J Pharmacol Exp Ther 2004 311 : 1179 1187.
    • (2004) J Pharmacol Exp Ther , vol.311 , pp. 1179-1187
    • Takane, H.1    Kobayashi, D.2    Hirota, T.3    Kiqawa, J.4    Terakawa, N.5    Otsubo, K.6    Ieiri, I.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.