Inositol 1,4,5- trisphosphate receptor function in Drosophila insulin producing cells

PLoS ONE

Volumn 4, Issue 8, 2009, Pages

  Agrawal, Neha ^a   Padmanabhan, Nisha ^a   Hasan, Gaiti ^a  

^a TATA INSTITUTE OF FUNDAMENTAL RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED RNA; INOSITOL 1,4,5 TRISPHOSPHATE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; INSULIN LIKE PEPTIDE 2; PEPTIDE HORMONE; PEPTIDES AND PROTEINS; PROTEIN DDC; TRANSCRIPTION FACTOR GAL4; UNCLASSIFIED DRUG; INSULIN; PRIMER DNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BODY SIZE; CONTROLLED STUDY; DROSOPHILA; FEEDING DISORDER; GENETIC STRAIN; GROWTH DISORDER; GROWTH REGULATION; INSULIN PRODUCING CELL; LARVAL DEVELOPMENT; LETHALITY; MICROBIAL VIABILITY; NERVE CELL; NONHUMAN; PHENOTYPE; POINT MUTATION; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PUPATION; REGULATORY MECHANISM; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SURVIVAL; TISSUE SPECIFICITY; ANIMAL; BIOSYNTHESIS; ENERGY METABOLISM; FEEDING BEHAVIOR; GENETICS; GROWTH, DEVELOPMENT AND AGING; IMMUNOHISTOCHEMISTRY; METABOLISM; MUTATION; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; DNA PRIMERS; DROSOPHILA; ENERGY METABOLISM; FEEDING BEHAVIOR; IMMUNOHISTOCHEMISTRY; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; INSULIN; MUTATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

EID: 69949106917     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0006652     Document Type: Article

References (58)

1. Berridge MJ, Bootman MD, Roderick HL (2003) Calcium signalling: dynamics, homeostasis and remodelling. Nat Rev Mol Cell Biol 4: 517-529.
2. Mikoshiba K (2007) IP3 receptor/Ca2+ channel: from discovery to new signaling concepts. J Neurochem 102: 1426-1446.
3. Venkatesh K, Hasan G (1997) Disruption of the IP3 receptor gene of Drosophila affects larval metamorphosis and ecdysone release. Curr Biol 7: 500-509.
4. Joshi R, Venkatesh K, Srinivas R, Nair S, Hasan G (2004) Genetic dissection of itpr gene function reveals a vital requirement in aminergic cells of Drosophila larvae. Genetics 166: 225-236.
5. Banerjee S, Lee J, Venkatesh K, Wu CF, Hasan G (2004) Loss of flight and associated neuronal rhythmicity in inositol 1,4,5-trisphosphate receptor mutants of Drosophila. J Neurosci 24: 7869-7878.
6. Rulifson EJ, Kim SK, Nusse R (2002) Ablation of insulin-producing neurons in flies: growth and diabetic phenotypes. Science 296: 1118-1120.
7. Garofalo RS (2002) Genetic analysis of insulin signaling in Drosophila. Trends Endocrinol Metab 13: 156-162.
8. Zinke I, Kirchner C, Chao LC, Tetzlaff MT, Pankratz MJ (1999) Suppression of food intake and growth by amino acids in Drosophila: the role of pumpless, a fat body expressed gene with homology to vertebrate glycine cleavage system. Development 126: 5275-5284.
9. Zinke I, Schutz CS, Katzenberger JD, Bauer M, Pankratz MJ (2002) Nutrient control of gene expression in Drosophila: microarray analysis of starvation and sugar-dependent response. Embo J 21: 6162-6173.
10. Fuss B, Becker T, Zinke I, Hoch M (2006) The cytohesin Steppke is essential for insulin signalling in Drosophila. Nature 444: 945-948.
11. McBrayer Z, Ono H, Shimell M, Parvy JP, Beckstead RB, et al. (2007) Prothoracicotropic hormone regulates developmental timing and body size in Drosophila. Dev Cell 13: 857-871.
12. Venkatesh K, Siddhartha G, Joshi R, Patel S, Hasan G (2001) Interactions between the inositol 1,4,5-trisphosphate and cyclic AMP signaling pathways regulate larval molting in Drosophila. Genetics 158: 309-318.
13. Janning W (1997) FlyView, a Drosophila image database, and other Drosophila databases. Semin Cell Dev Biol 8: 469-475.
14. Gates J, Lam G, Ortiz JA, Losson R, Thummel CS (2004) rigor mortis encodes a novel nuclear receptor interacting protein required for ecdysone signaling during Drosophila larval development. Development 131: 25-36.
15. Fellner SK, Rybczynski R, Gilbert LI (2005) Ca2+ signaling in prothoracicotropic hormone-stimulated prothoracic gland cells of Manduca sexta: evidence for mobilization and entry mechanisms. Insect Biochem Mol Biol 35: 263-275.
16. Won JG, Orth DN (1995) Role of inositol trisphosphate-sensitive calcium stores in the regulation of adrenocorticotropin secretion by perifused rat anterior pituitary cells. Endocrinology 136: 5399-5408.
17. Cherradi N, Brandenburger Y, Rossier MF, Capponi AM (1998) Regulation of mineralocorticoid biosynthesis by calcium and the StAR protein. Endocr Res 24: 355-362.
18. Lundell MJ, Hirsh J (1994) Temporal and spatial development of serotonin and dopamine neurons in the Drosophila CNS. Dev Biol 165: 385-396.
19. Brogiolo W, Stocker H, Ikeya T, Rintelen F, Fernandez R, et al. (2001) An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control. Curr Biol 11: 213-221.
20. Friggi-Grelin F, Coulom H, Meller M, Gomez D, Hirsh J, et al. (2003) Targeted gene expression in Drosophila dopaminergic cells using regulatory sequences from tyrosine hydroxylase. J Neurobiol 54: 618-627.
21. Melcher C, Pankratz MJ (2005) Candidate gustatory interneurons modulating feeding behavior in the Drosophila brain. PLoS Biol 3: e305.
22. Kaplan DD, Zimmermann G, Suyama K, Meyer T, Scott MP (2008) A nucleostemin family GTPase, NS3, acts in serotonergic neurons to regulate insulin signaling and control body size. Genes Dev 22: 1877-1893.
23. Dietzl G, Chen D, Schnorrer F, Su KC, Barinova Y, et al. (2007) A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila. Nature 448: 151-156.
24. Matsumoto M, Nakagawa T, Inoue T, Nagata E, Tanaka K, et al. (1996) Ataxia and epileptic seizures in mice lacking type 1 inositol 1,4,5-trisphosphate receptor. Nature 379: 168-171.
25. Street VA, Bosma MM, Demas VP, Regan MR, Lin DD, et al. (1997) The type 1 inositol 1,4,5-trisphosphate receptor gene is altered in the opisthotonos mouse. J Neurosci 17: 635-645.
26. Matsumoto M, Nagata E (1999) Type 1 inositol 1,4,5-trisphosphate receptor knock-out mice: their phenotypes and their meaning in neuroscience and clinical practice. J Mol Med 77: 406-411.
27. Futatsugi A, Nakamura T, Yamada MK, Ebisui E, Nakamura K, et al. (2005) IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism. Science 309: 2232-2234.
28. Greenspan RJ (2001) The flexible genome. Nat Rev Genet 2: 383-387.
29. Marder E, Goaillard JM (2006) Variability, compensation and homeostasis in neuron and network function. Nat Rev Neurosci 7: 563-574.
30. Biden TJ, Prentki M, Irvine RF, Berridge MJ, Wollheim CB (1984) Inositol 1,4,5-trisphosphate mobilizes intracellular Ca2+ from permeabilized insulin-secreting cells. Biochem J 223: 467-473.
31. Prentki M, Corkey BE, Matschinsky FM (1985) Inositol 1,4,5-trisphosphate and the endoplasmic reticulum Ca2+ cycle of a rat insulinoma cell line. J Biol Chem 260: 9185-9190.
32. Hagar RE, Ehrlich BE (2000) Regulation of the type III InsP3 receptor and its role in beta cell function. Cell Mol Life Sci 57: 1938-1949.
33. Barker CJ, Nilsson T, Kirk CJ, Michell RH, Berggren PO (1994) Simultaneous oscillations of cytoplasmic free Ca2+ concentration and Ins(1,4,5)P3 concentration in mouse pancreatic beta-cells. Biochem J 297 ( Pt2): 265-268.
34. Tamarina NA, Kuznetsov A, Rhodes CJ, Bindokas VP, Philipson LH (2005) Inositol (1,4,5)-trisphosphate dynamics and intracellular calcium oscillations in pancreatic beta-cells. Diabetes 54: 3073-3081.
35. Ahren B (2000) Autonomic regulation of islet hormone secretion-implications for health and disease. Diabetologia 43: 393-410.
36. Gilon P, Henquin JC (2001) Mechanisms and physiological significance of the cholinergic control of pancreatic beta-cell function. Endocr Rev 22: 565-604.
37. Gautam D, Han SJ, Hamdan FF, Jeon J, Li B, et al. (2006) A critical role for beta cell M3 muscarinic acetylcholine receptors in regulating insulin release and blood glucose homeostasis in vivo. Cell Metab 3: 449-461.
38. Britton JS, Lockwood WK, Li L, Cohen SM, Edgar BA (2002) Drosophila's insulin/PI3-kinase pathway coordinates cellular metabolism with nutritional conditions. Dev Cell 2: 239-249.
39. Junger MA, Rintelen F, Stocker H, Wasserman JD, Vegh M, et al. (2003) The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling. J Biol 2: 20.
40. Kramer JM, Davidge JT, Lockyer JM, Staveley BE (2003) Expression of Drosophila FOXO regulates growth and can phenocopy starvation. BMC Dev Biol 3: 5.
41. Monastirioti M (1999) Biogenic amine systems in the fruit fly Drosophila melanogaster. Microsc Res Tech 45: 106-121.
42. Neckameyer WS, Coleman CM, Eadie S, Goodwin SF (2007) Compartmentalization of neuronal and peripheral serotonin synthesis in Drosophila melanogaster. Genes Brain Behav 6: 756-769.
43. Schlegel A, Stainier DY (2007) Lessons from "lower" organisms: what worms, flies, and zebrafish can teach us about human energy metabolism. PLoS Genet 3: e199.
44. Tecott LH (2007) Serotonin and the orchestration of energy balance. Cell Metab 6: 352-361.
45. Walker DS, Gower NJ, Ly S, Bradley GL, Baylis HA (2002) Regulated disruption of inositol 1,4,5-trisphosphate signaling in Caenorhabditis elegans reveals new functions in feeding and embryogenesis. Mol Biol Cell 13: 1329-1337.
46. Garofalo RS, Rosen OM (1988) Tissue localization of Drosophila melanogaster insulin receptor transcripts during development. Mol Cell Biol 8: 1638-1647.
47. Gorczyca M, Augart C, Budnik V (1993) Insulin-like receptor and insulin-like peptide are localized at neuromuscular junctions in Drosophila. J Neurosci 13: 3692-3704.
48. Belgacem YH, Martin JR (2006) Disruption of insulin pathways alters trehalose level and abolishes sexual dimorphism in locomotor activity in Drosophila. J Neurobiol 66: 19-32.
49. Bunin MA, Wightman RM (1999) Paracrine neurotransmission in the CNS: involvement of 5-HT. Trends Neurosci 22: 377-382.
50. Sykes PA, Condron BG (2005) Development and sensitivity to serotonin of Drosophila serotonergic varicosities in the central nervous system. Dev Biol 286: 207-216.
51. Yuan Q, Lin F, Zheng X, Sehgal A (2005) Serotonin modulates circadian entrainment in Drosophila. Neuron 47: 115-127.
52. Nichols CD (2007) 5-HT2 receptors in Drosophila are expressed in the brain and modulate aspects of circadian behaviors. Dev Neurobiol 67: 752-763.
53. Zhou L, Sutton GM, Rochford JJ, Semple RK, Lam DD, et al. (2007) Serotonin 2C receptor agonists improve type 2 diabetes via melanocortin-4 receptor signaling pathways. Cell Metab 6: 398-405.
54. Ruaud AF, Thummel CS (2008) Serotonin and insulin signaling team up to control growth in Drosophila. Genes Dev 22: 1851-1855.
55. Li H, Chaney S, Roberts IJ, Forte M, Hirsh J (2000) Ectopic G-protein expression in dopamine and serotonin neurons blocks cocaine sensitization in Drosophila melanogaster. Curr Biol 10: 211-214.
56. Suster ML, Bate M (2002) Embryonic assembly of a central pattern generator without sensory input. Nature 416: 174-178.
57. Lorentzos P, Kaiser T, Kennerson ML, Nicholson GA (2003) A rapid and definitive test for Charcot-Marie-Tooth 1A and hereditary neuropathy with liability to pressure palsies using multiplexed real-time PCR. Genet Test 7: 135-138.
58. Srikanth S, Wang Z, Tu H, Nair S, Mathew MK, et al. (2004) Functional properties of the Drosophila melanogaster inositol 1,4,5-trisphosphate receptor mutants. Biophys J 86: 3634-3646.