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Volumn 39, Issue 9, 2009, Pages 910-920

Effects of estrogen and androgen deprivation on the progression of non-alcoholic steatohepatitis (NASH) in male Sprague - Dawley rats

Author keywords

Androgen; Estrogen; Non alcoholic fatty liver disease; Non alcoholic steatohepatitis

Indexed keywords

ALANINE AMINOTRANSFERASE; ANDROGEN; CHOLESTEROL; ESTROGEN; ESTROGEN RECEPTOR ALPHA; FAS ANTIGEN; FLUTAMIDE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TAMOXIFEN; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; UNCOUPLING PROTEIN 2;

EID: 69949096681     PISSN: 13866346     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1872-034X.2009.00512.x     Document Type: Article
Times cited : (15)

References (40)
  • 3
    • 0036829092 scopus 로고    scopus 로고
    • AGA technical review on nonalcoholic fatty liver disease
    • Nov
    • Sanyal AJ. AGA technical review on nonalcoholic fatty liver disease. Gastroenterology 2002 Nov; 123: 1705-25.
    • (2002) Gastroenterology , vol.123 , pp. 1705-1725
    • Sanyal, A.J.1
  • 4
    • 0033562693 scopus 로고    scopus 로고
    • Non-alcoholic steatohepatitis: Another disease of affluence
    • (May 15)
    • James O, Day C. Non-alcoholic steatohepatitis: Another disease of affluence. Lancet 1999 (May 15); 353: 1634-6.
    • (1999) Lancet , vol.353 , pp. 1634-1636
    • James, O.1    Day, C.2
  • 6
    • 36349006497 scopus 로고    scopus 로고
    • The impact of fat distribution on the severity of nonalcoholic fatty liver disease and metabolic syndrome
    • Oct
    • Cheung O, Kapoor A, Puri P et al. The impact of fat distribution on the severity of nonalcoholic fatty liver disease and metabolic syndrome. Hepatology 2007 Oct; 46: 1091-100.
    • (2007) Hepatology , vol.46 , pp. 1091-1100
    • Cheung, O.1    Kapoor, A.2    Puri, P.3
  • 7
    • 0037142082 scopus 로고    scopus 로고
    • Protective effects of estrogen on the cardiovascular system
    • discussion 7E-8E
    • Mendelsohn ME. Protective effects of estrogen on the cardiovascular system. Am J Cardiol 2002; 89: 12E-7E; discussion 7E-8E.
    • (2002) Am J Cardiol , vol.89
    • Mendelsohn, M.E.1
  • 8
    • 1642505593 scopus 로고    scopus 로고
    • Estrogen replacement reverses the hepatic steatosis phenotype in the male aromatase knockout mouse
    • Hewitt KN, Pratis K, Jones ME, Simpson ER. Estrogen replacement reverses the hepatic steatosis phenotype in the male aromatase knockout mouse. Endocrinology 2004; 145: 1842-8.
    • (2004) Endocrinology , vol.145 , pp. 1842-1848
    • Hewitt, K.N.1    Pratis, K.2    Jones, M.E.3    Simpson, E.R.4
  • 9
    • 12944276957 scopus 로고    scopus 로고
    • Aromatase-deficient (ArKO) mice have a phenotype of increased adiposity
    • Jones M, Thorburn A, Britt K. Aromatase-deficient (ArKO) mice have a phenotype of increased adiposity. Proc Natl Acad Sci USA 2000; 97: 12735-40.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 12735-12740
    • Jones, M.1    Thorburn, A.2    Britt, K.3
  • 10
    • 0028143234 scopus 로고
    • Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man
    • Smith EP, Boyd J, Frank GR et al. Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man. N Engl J Med 1994; 331: 1056-61.
    • (1994) N Engl J Med , vol.331 , pp. 1056-1061
    • Smith, E.P.1    Boyd, J.2    Frank, G.R.3
  • 11
    • 10744225853 scopus 로고    scopus 로고
    • Dysmetabolic syndrome in a man with a novel mutation of the aromatase gene: Effects of testosterone, alendronate, and estradiol treatment
    • Jan
    • Maffei L, Murata Y, Rochira V et al. Dysmetabolic syndrome in a man with a novel mutation of the aromatase gene: Effects of testosterone, alendronate, and estradiol treatment. J Clin Endocrinol Metab 2004 Jan; 89: 61-70.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 61-70
    • Maffei, L.1    Murata, Y.2    Rochira, V.3
  • 12
    • 23444451889 scopus 로고    scopus 로고
    • Prevalence of and risk factors for fatty liver in a general population of Shanghai, China
    • Sep
    • Fan JG, Zhu J, Li XJ et al. Prevalence of and risk factors for fatty liver in a general population of Shanghai, China. J Hepatol 2005 Sep; 43: 508-14.
    • (2005) J Hepatol , vol.43 , pp. 508-514
    • Fan, J.G.1    Zhu, J.2    Li, X.J.3
  • 13
    • 10644220306 scopus 로고    scopus 로고
    • Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity
    • Dec
    • Browning JD, Szczepaniak LS, Dobbins R et al. Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity. Hepatology 2004 Dec; 40: 1387-95.
    • (2004) Hepatology , vol.40 , pp. 1387-1395
    • Browning, J.D.1    Szczepaniak, L.S.2    Dobbins, R.3
  • 14
    • 0036019075 scopus 로고    scopus 로고
    • Tamoxifen-induced nonalcoholic steatohepatitis in breast cancer patients treated with adjuvant tamoxifen
    • May
    • Nemoto Y, Saibara T, Ogawa Y et al. Tamoxifen-induced nonalcoholic steatohepatitis in breast cancer patients treated with adjuvant tamoxifen. Intern Med 2002 May; 41: 345-50.
    • (2002) Intern Med , vol.41 , pp. 345-350
    • Nemoto, Y.1    Saibara, T.2    Ogawa, Y.3
  • 15
    • 0037216370 scopus 로고    scopus 로고
    • Effects of tamoxifen on hepatic fat content and the development of hepatic steatosis in patients with breast cancer: High frequency of involvement and rapid reversal after completion of tamoxifen therapy
    • Jan
    • Nishino M, Hayakawa K, Nakamura Y, Morimoto T, Mukaihara S. Effects of tamoxifen on hepatic fat content and the development of hepatic steatosis in patients with breast cancer: High frequency of involvement and rapid reversal after completion of tamoxifen therapy. AJR Am J Roentgenol 2003 Jan; 180: 129-34.
    • (2003) AJR Am J Roentgenol , vol.180 , pp. 129-134
    • Nishino, M.1    Hayakawa, K.2    Nakamura, Y.3    Morimoto, T.4    Mukaihara, S.5
  • 16
    • 0027429548 scopus 로고
    • Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene
    • Lubahn D, Moyer J, Golding T, Couse J, Korach K, Smithies O. Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene. Proc Natl Acad Sci USA 1993; 90: 11162-6.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11162-11166
    • Lubahn, D.1    Moyer, J.2    Golding, T.3    Couse, J.4    Korach, K.5    Smithies, O.6
  • 17
    • 0342445418 scopus 로고    scopus 로고
    • Postnatal sex reversal of the ovaries in mice lacking estrogen receptors alpha and beta
    • Couse JF, Hewitt SC, Bunch DO et al. Postnatal sex reversal of the ovaries in mice lacking estrogen receptors alpha and beta. Science 1999; 286: 2328-31.
    • (1999) Science , vol.286 , pp. 2328-2331
    • Couse, J.F.1    Hewitt, S.C.2    Bunch, D.O.3
  • 18
    • 0031798630 scopus 로고    scopus 로고
    • Androgen receptors in human preadipocytes and adipocytes: Regional specificities and regulation by sex steroids
    • Jun
    • Dieudonne MN, Pecquery R, Boumediene A, Leneveu MC, Giudicelli Y. Androgen receptors in human preadipocytes and adipocytes: Regional specificities and regulation by sex steroids. Am J Physiol 1998 Jun; 274: C1645-52.
    • (1998) Am J Physiol , vol.274
    • Dieudonne, M.N.1    Pecquery, R.2    Boumediene, A.3    Leneveu, M.C.4    Giudicelli, Y.5
  • 19
    • 0038823605 scopus 로고    scopus 로고
    • Testosterone supplementation in men with type 2 diabetes, visceral obesity and partial androgen deficiency
    • Mar
    • Boyanov MA, Boneva Z, Christov VG. Testosterone supplementation in men with type 2 diabetes, visceral obesity and partial androgen deficiency. Aging Male 2003 Mar; 6: 1-7.
    • (2003) Aging Male , vol.6 , pp. 1-7
    • Boyanov, M.A.1    Boneva, Z.2    Christov, V.G.3
  • 20
    • 33745684473 scopus 로고    scopus 로고
    • Testosterone replacement therapy improves insulin resistance, glycaemic control, visceral adiposity and hypercholesterolaemia in hypogonadal men with type 2 diabetes
    • Jun
    • Kapoor D, Goodwin E, Channer KS, Jones TH. Testosterone replacement therapy improves insulin resistance, glycaemic control, visceral adiposity and hypercholesterolaemia in hypogonadal men with type 2 diabetes. Eur J Endocrinol 2006 Jun; 154: 899-906.
    • (2006) Eur J Endocrinol , vol.154 , pp. 899-906
    • Kapoor, D.1    Goodwin, E.2    Channer, K.S.3    Jones, T.H.4
  • 21
    • 16244382558 scopus 로고    scopus 로고
    • Androgen receptor null male mice develop late-onset obesity caused by decreased energy expenditure and lipolytic activity but show normal insulin sensitivity with high adiponectin secretion
    • Apr
    • Fan W, Yanase T, Nomura M et al. Androgen receptor null male mice develop late-onset obesity caused by decreased energy expenditure and lipolytic activity but show normal insulin sensitivity with high adiponectin secretion. Diabetes 2005 Apr; 54: 1000-8.
    • (2005) Diabetes , vol.54 , pp. 1000-1008
    • Fan, W.1    Yanase, T.2    Nomura, M.3
  • 23
    • 46249091950 scopus 로고    scopus 로고
    • Increased hepatic steatosis and insulin resistance in mice lacking hepatic androgen receptor
    • Jun
    • Lin HY, Yu IC, Wang RS et al. Increased hepatic steatosis and insulin resistance in mice lacking hepatic androgen receptor. Hepatology 2008 Jun; 47: 1924-35.
    • (2008) Hepatology , vol.47 , pp. 1924-1935
    • Lin, H.Y.1    Yu, I.C.2    Wang, R.S.3
  • 24
    • 6044260243 scopus 로고    scopus 로고
    • Case of NASH exacerbated after testectomy due to seminoma
    • Jun
    • Morizono S, Nakamuta M, Ohta S et al. [Case of NASH exacerbated after testectomy due to seminoma]. Fukuoka Igaku Zasshi 2004 Jun; 95: 146-51.
    • (2004) Fukuoka Igaku Zasshi , vol.95 , pp. 146-151
    • Morizono, S.1    Nakamuta, M.2    Ohta, S.3
  • 25
    • 0032974688 scopus 로고    scopus 로고
    • ApoA1 reduces free cholesterol accumulation in atherosclerotic lesions of ApoE-deficient mice transplanted with ApoE-expressing macrophages
    • Mar
    • Boisvert W, Black A, Curtiss L. ApoA1 reduces free cholesterol accumulation in atherosclerotic lesions of ApoE-deficient mice transplanted with ApoE-expressing macrophages. Arterioscler Thromb Vasc Biol 1999 Mar; 19: 525-30.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 525-530
    • Boisvert, W.1    Black, A.2    Curtiss, L.3
  • 26
    • 17744375346 scopus 로고    scopus 로고
    • Altered structure and function of reproductive organs in transgenic male mice overexpressing human aromatase
    • Jun
    • Li X, Nokkala E, Yan W et al. Altered structure and function of reproductive organs in transgenic male mice overexpressing human aromatase. Endocrinology 2001 Jun; 142: 2435-42.
    • (2001) Endocrinology , vol.142 , pp. 2435-2442
    • Li, X.1    Nokkala, E.2    Yan, W.3
  • 27
    • 0002496513 scopus 로고    scopus 로고
    • Recovery of DNA from Agarose gels: Electrophoresis onto DEAE-cellulose membranes
    • In: 3rd edn. New York, Cold Spring Harbor Laboratory Press
    • Sambrook J, Russel D. Recovery of DNA from Agarose gels: Electrophoresis onto DEAE-cellulose membranes. In: Molecular Cloning: A Laboratory Manual, 3rd edn. New York, Cold Spring Harbor Laboratory Press, 2001; 518-22.
    • (2001) Molecular Cloning: A Laboratory Manual , pp. 518-522
    • Sambrook, J.1    Russel, D.2
  • 28
    • 32644436182 scopus 로고    scopus 로고
    • Transgenic mice expressing p450 aromatase as a model for male infertility associated with chronic inflammation in the testis
    • Mar
    • Li X, Strauss L, Kaatrasalo A et al. Transgenic mice expressing p450 aromatase as a model for male infertility associated with chronic inflammation in the testis. Endocrinology 2006 Mar; 147: 1271-7.
    • (2006) Endocrinology , vol.147 , pp. 1271-1277
    • Li, X.1    Strauss, L.2    Kaatrasalo, A.3
  • 29
    • 0031028140 scopus 로고    scopus 로고
    • Initiation of liver growth by tumor necrosis factor: Deficient liver regeneration in mice lacking type I tumor necrosis factor receptor
    • (Feb 18)
    • Yamada Y, Kirillova I, Peschon JJ, Fausto N. Initiation of liver growth by tumor necrosis factor: Deficient liver regeneration in mice lacking type I tumor necrosis factor receptor. Proc Natl Acad Sci USA 1997 (Feb 18); 94: 1441-6.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 1441-1446
    • Yamada, Y.1    Kirillova, I.2    Peschon, J.J.3    Fausto, N.4
  • 30
    • 16444365837 scopus 로고    scopus 로고
    • From presence to consciousness through virtual reality
    • Apr
    • Sanchez-Vives MV, Slater M. From presence to consciousness through virtual reality. Nat Rev Neurosci 2005 Apr; 6: 332-9.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 332-339
    • Sanchez-Vives, M.V.1    Slater, M.2
  • 31
    • 0032492439 scopus 로고    scopus 로고
    • Tamoxifen-induced fatty liver in patients with breast cancer
    • (Mar 7)
    • Ogawa Y, Murata Y, Nishioka A, Inomata T, Yoshida S. Tamoxifen-induced fatty liver in patients with breast cancer. Lancet 1998 (Mar 7); 351: 725.
    • (1998) Lancet , vol.351 , pp. 725
    • Ogawa, Y.1    Murata, Y.2    Nishioka, A.3    Inomata, T.4    Yoshida, S.5
  • 32
    • 21744460524 scopus 로고    scopus 로고
    • Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis
    • Jul
    • Lelliott CJ, Lopez M, Curtis RK et al. Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis. FASEB J 2005 Jul; 19: 1108-19.
    • (2005) FASEB J , vol.19 , pp. 1108-1119
    • Lelliott, C.J.1    Lopez, M.2    Curtis, R.K.3
  • 33
    • 34247203727 scopus 로고    scopus 로고
    • Tamoxifen inhibits topoisomerases, depletes mitochondrial DNA, and triggers steatosis in mouse liver
    • May
    • Larosche I, Letteron P, Fromenty B et al. Tamoxifen inhibits topoisomerases, depletes mitochondrial DNA, and triggers steatosis in mouse liver. J Pharmacol Exp Ther 2007 May; 321: 526-35.
    • (2007) J Pharmacol Exp Ther , vol.321 , pp. 526-535
    • Larosche, I.1    Letteron, P.2    Fromenty, B.3
  • 34
    • 34447327216 scopus 로고    scopus 로고
    • Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production
    • (Jul 6)
    • Naugler WE, Sakurai T, Kim S et al. Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production. Science 2007 (Jul 6); 317: 121-4.
    • (2007) Science , vol.317 , pp. 121-124
    • Naugler, W.E.1    Sakurai, T.2    Kim, S.3
  • 35
    • 0033605261 scopus 로고    scopus 로고
    • Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion
    • (Feb 26)
    • Chavin KD, Yang S, Lin HZ et al. Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion. J Biol Chem 1999 (Feb 26); 274: 5692-700.
    • (1999) J Biol Chem , vol.274 , pp. 5692-5700
    • Chavin, K.D.1    Yang, S.2    Lin, H.Z.3
  • 36
    • 0036207189 scopus 로고    scopus 로고
    • Obesity-related fatty liver is unchanged in mice deficient for mitochondrial uncoupling protein 2
    • Apr
    • Baffy G, Zhang CY, Glickman JN, Lowell BB. Obesity-related fatty liver is unchanged in mice deficient for mitochondrial uncoupling protein 2. Hepatology 2002 Apr; 35: 753-61.
    • (2002) Hepatology , vol.35 , pp. 753-761
    • Baffy, G.1    Zhang, C.Y.2    Glickman, J.N.3    Lowell, B.B.4
  • 37
    • 0141786790 scopus 로고    scopus 로고
    • Oxidative stress, KLF6 and transforming growth factor-beta up-regulation differentiate non-alcoholic steatohepatitis progressing to fibrosis from uncomplicated steatosis in rats
    • Oct
    • Starkel P, Sempoux C, Leclercq I et al. Oxidative stress, KLF6 and transforming growth factor-beta up-regulation differentiate non-alcoholic steatohepatitis progressing to fibrosis from uncomplicated steatosis in rats. J Hepatol 2003 Oct; 39: 538-46.
    • (2003) J Hepatol , vol.39 , pp. 538-546
    • Starkel, P.1    Sempoux, C.2    Leclercq, I.3
  • 38
    • 0035084699 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis: Association of insulin resistance and mitochondrial abnormalities
    • Apr
    • Sanyal AJ, Campbell-Sargent C, Mirshahi F et al. Nonalcoholic steatohepatitis: Association of insulin resistance and mitochondrial abnormalities. Gastroenterology 2001 Apr; 120: 1183-92.
    • (2001) Gastroenterology , vol.120 , pp. 1183-1192
    • Sanyal, A.J.1    Campbell-Sargent, C.2    Mirshahi, F.3
  • 39
    • 0022007068 scopus 로고
    • Elevated hepatic mitochondrial and peroxisomal oxidative capacities in fed and starved adult obese (ob/ob) mice
    • (Oct 15)
    • Brady LJ, Brady PS, Romsos DR, Hoppel CL. Elevated hepatic mitochondrial and peroxisomal oxidative capacities in fed and starved adult obese (ob/ ob) mice. Biochem J 1985 (Oct 15); 231: 439-44.
    • (1985) Biochem J , vol.231 , pp. 439-444
    • Brady, L.J.1    Brady, P.S.2    Romsos, D.R.3    Hoppel, C.L.4
  • 40
    • 21644463596 scopus 로고    scopus 로고
    • Mechanism responsible for the salutary effects of flutamide on cardiac performance after trauma-hemorrhagic shock: Upregulation of cardiomyocyte estrogen receptors
    • Jul
    • Yu HP, Yang S, Choudhry MA, Hsieh YC, Bland KI, Chaudry IH. Mechanism responsible for the salutary effects of flutamide on cardiac performance after trauma-hemorrhagic shock: Upregulation of cardiomyocyte estrogen receptors. Surgery 2005 Jul; 138: 85-92.
    • (2005) Surgery , vol.138 , pp. 85-92
    • Yu, H.P.1    Yang, S.2    Choudhry, M.A.3    Hsieh, Y.C.4    Bland, K.I.5    Chaudry, I.H.6


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