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Volumn 7, Issue , 2009, Pages

Combined therapy with cyclophosphamide and DNA preparation inhibits the tumor growth in mice

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHOSPHAMIDE; DNA FRAGMENT; DOUBLE STRANDED DNA; GENOMIC DNA; TUMOR ANTIGEN;

EID: 69549129482     PISSN: None     EISSN: 14790556     Source Type: Journal    
DOI: 10.1186/1479-0556-7-12     Document Type: Article
Times cited : (11)

References (37)
  • 1
    • 33746092105 scopus 로고    scopus 로고
    • Chemotherapy and chemosensitization of non-small cell lung cancer with a novel immunomodulatory oligonucleotide targeting Toll-like receptor 9
    • 10.1158/1535-7163.MCT-06-0094 16818518
    • Wang H Rayburn ER Wang W Kandimalla ER Agrawal S Zhang R Chemotherapy and chemosensitization of non-small cell lung cancer with a novel immunomodulatory oligonucleotide targeting Toll-like receptor 9 Mol Cancer Ther 2006, 5:1585-1592. 10.1158/1535-7163.MCT-06-0094 16818518
    • (2006) Mol Cancer Ther , vol.5 , pp. 1585-1592
    • Wang, H.1    Rayburn, E.R.2    Wang, W.3    Kandimalla, E.R.4    Agrawal, S.5    Zhang, R.6
  • 3
    • 33749490571 scopus 로고    scopus 로고
    • Innate immune recognition of, and regulation by, DNA
    • 10.1016/j.it.2006.09.002 16979939
    • Ishii KJ Akira S Innate immune recognition of, and regulation by, DNA Trends Immunol 2006, 27:525-532. 10.1016/j.it.2006.09.002 16979939
    • (2006) Trends Immunol , vol.27 , pp. 525-532
    • Ishii, K.J.1    Akira, S.2
  • 4
    • 34248169629 scopus 로고    scopus 로고
    • Development of TLR9 agonists for cancer therapy
    • 10.1172/JCI31414 1857270 17476348
    • Krieg AM Development of TLR9 agonists for cancer therapy J Clin Invest 2007, 117:1184-1194. 10.1172/JCI31414 1857270 17476348
    • (2007) J Clin Invest , vol.117 , pp. 1184-1194
    • Krieg, A.M.1
  • 5
    • 35349016235 scopus 로고    scopus 로고
    • Recognition of microorganisms and activation of the immune response
    • 10.1038/nature06246 17943118
    • Medzhitov R Recognition of microorganisms and activation of the immune response Nature 2007, 449:819-826. 10.1038/nature06246 17943118
    • (2007) Nature , vol.449 , pp. 819-826
    • Medzhitov, R.1
  • 6
    • 69549151988 scopus 로고    scopus 로고
    • Role of Toll-like receptors in tissue repair and carcinogenesis
    • Rakoff-Naum S Medzhitov R Role of Toll-like receptors in tissue repair and carcinogenesis Biokhimia 2008, 73:690-698.
    • (2008) Biokhimia , vol.73 , pp. 690-698
    • Rakoff-Naum, S.1    Medzhitov, R.2
  • 7
    • 0033027749 scopus 로고    scopus 로고
    • CpG DNA and LPS induce distinct patterns of activation in human monocytes
    • 10.1038/sj.gt.3300880 10505115
    • Hartmann G Krieg AM CpG DNA and LPS induce distinct patterns of activation in human monocytes Gene Ther 1999, 6:893-903. 10.1038/ sj.gt.3300880 10505115
    • (1999) Gene Ther , vol.6 , pp. 893-903
    • Hartmann, G.1    Krieg, A.M.2
  • 8
    • 14044257261 scopus 로고    scopus 로고
    • Variegation of the immune response with dendritic cells and pathogen recognition receptors
    • 15728447
    • Pulendran B Variegation of the immune response with dendritic cells and pathogen recognition receptors J Immunol 2005, 174:2457-2465. 15728447
    • (2005) J Immunol , vol.174 , pp. 2457-2465
    • Pulendran, B.1
  • 9
    • 0004753309 scopus 로고    scopus 로고
    • Phase II trial of intravenous endotoxin in patients with colorectal and non-small cell lung cancer
    • 10.1016/0959-8049(96)00186-4 8983279
    • Otto F Schmid P Mackensen A Wehr U Seiz A Braun M Galanos C Mertelsmann R Engelhardt R Phase II trial of intravenous endotoxin in patients with colorectal and non-small cell lung cancer Eur J Cancer 1996, 32A:1712-1718. 10.1016/0959-8049(96)00186-4 8983279
    • (1996) Eur J Cancer , vol.32 A , pp. 1712-1718
    • Otto, F.1    Schmid, P.2    Mackensen, A.3    Wehr, U.4    Seiz, A.5    Braun, M.6    Galanos, C.7    Mertelsmann, R.8    Engelhardt, R.9
  • 10
    • 17644372733 scopus 로고    scopus 로고
    • IPC: Professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors
    • 10.1146/annurev.immunol.23.021704.115633 15771572
    • Liu YJ IPC: Professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors Annu Rev Immunol 2005, 23:275-306. 10.1146/annurev.immunol.23.021704.115633 15771572
    • (2005) Annu Rev Immunol , vol.23 , pp. 275-306
    • Liu, Y.J.1
  • 11
    • 31344461659 scopus 로고    scopus 로고
    • Innate immune recognition of viral infection
    • 10.1038/ni1303 16424890
    • Kawai T Akira S Innate immune recognition of viral infection Nat Immunol 2006, 7:131-137. 10.1038/ni1303 16424890
    • (2006) Nat Immunol , vol.7 , pp. 131-137
    • Kawai, T.1    Akira, S.2
  • 12
    • 33645286546 scopus 로고    scopus 로고
    • Regulatory T cells, tumour immunity and immunotherapy
    • 10.1038/nri1806 16557261
    • Zou W Regulatory T cells, tumour immunity and immunotherapy Nat Rev Immunol 2006, 6:295-307. 10.1038/nri1806 16557261
    • (2006) Nat Rev Immunol , vol.6 , pp. 295-307
    • Zou, W.1
  • 13
    • 2542421791 scopus 로고    scopus 로고
    • Cellular immunity in breast cancer patients completing taxane treatment
    • 10.1158/1078-0432.CCR-1016-03 15161695
    • Carson WE 3rd Shapiro CL Crespin TR Thornton LM Andersen BL Cellular immunity in breast cancer patients completing taxane treatment Clin Cancer Res 2004, 10:3401-3409. 10.1158/1078-0432.CCR-1016-03 15161695
    • (2004) Clin Cancer Res , vol.10 , pp. 3401-3409
    • Carson III, W.E.1    Shapiro, C.L.2    Crespin, T.R.3    Thornton, L.M.4    Andersen, B.L.5
  • 14
    • 24744432528 scopus 로고    scopus 로고
    • Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine
    • 10.1182/blood-2005-02-0642 15914560
    • Beyer M Kochanek M Darabi K Popov A Jensen M Endl E Knolle PA Thomas RK von Bergwelt-Baildon M Debey S Hallek M Schultze JL Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine Blood 2005, 106:2018-2025. 10.1182/blood-2005-02-0642 15914560
    • (2005) Blood , vol.106 , pp. 2018-2025
    • Beyer, M.1    Kochanek, M.2    Darabi, K.3    Popov, A.4    Jensen, M.5    Endl, E.6    Knolle, P.A.7    Thomas, R.K.8    von Bergwelt-Baildon, M.9    Debey, S.10    Hallek, M.11    Schultze, J.L.12
  • 15
    • 33644789357 scopus 로고    scopus 로고
    • Chemo-immunotherapy of metastatic colorectal carcinoma with gemcitabine plus FOLFOX 4 followed by subcutaneous granulocyte macrophage colony-stimulating factor and interleukin-2 induces strong immunologic and antitumor activity in metastatic colon cancer patients
    • 10.1200/JCO.2005.12.147 16061910
    • Correale P Cusi MG Tsang KY Del Vecchio MT Marsili S Placa ML Intrivici C Aquino A Micheli L Nencini C Ferrari F Giorgi G Bonmassar E Francini G Chemo-immunotherapy of metastatic colorectal carcinoma with gemcitabine plus FOLFOX 4 followed by subcutaneous granulocyte macrophage colony-stimulating factor and interleukin-2 induces strong immunologic and antitumor activity in metastatic colon cancer patients J Clin Oncol 2005, 23:8950-8958. 10.1200/JCO.2005.12.147 16061910
    • (2005) J Clin Oncol , vol.23 , pp. 8950-8958
    • Correale, P.1    Cusi, M.G.2    Tsang, K.Y.3    Del Vecchio, M.T.4    Marsili, S.5    Placa, M.L.6    Intrivici, C.7    Aquino, A.8    Micheli, L.9    Nencini, C.10    Ferrari, F.11    Giorgi, G.12    Bonmassar, E.13    Francini, G.14
  • 16
    • 24944478531 scopus 로고    scopus 로고
    • Leveraging the activity of tumor vaccines with cytotoxic chemotherapy
    • 10.1158/0008-5472.CAN-05-1797 16166275
    • Emens LA Jaffee EM Leveraging the activity of tumor vaccines with cytotoxic chemotherapy Cancer Res 2005, 65:8059-8064. 10.1158/ 0008-5472.CAN-05-1797 16166275
    • (2005) Cancer Res , vol.65 , pp. 8059-8064
    • Emens, L.A.1    Jaffee, E.M.2
  • 18
    • 1642378018 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative
    • 10.1002/eji.200324181 14768038
    • Ghiringhelli F Larmonier N Schmitt E Parcellier A Cathelin D Garrido C Chauffert B Solary E Bonnotte B Martin F CD4+CD25+ regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative Eur J Immunol 2004, 34:336-344. 10.1002/eji.200324181 14768038
    • (2004) Eur J Immunol , vol.34 , pp. 336-344
    • Ghiringhelli, F.1    Larmonier, N.2    Schmitt, E.3    Parcellier, A.4    Cathelin, D.5    Garrido, C.6    Chauffert, B.7    Solary, E.8    Bonnotte, B.9    Martin, F.10
  • 19
    • 18344375283 scopus 로고    scopus 로고
    • Immunotherapy and chemotherapy - A practical partnership
    • 10.1038/nrc1613 15864281
    • Lake RA Robinson BW Immunotherapy and chemotherapy - a practical partnership Nat Rev Cancer 2005, 5:397-405. 10.1038/nrc1613 15864281
    • (2005) Nat Rev Cancer , vol.5 , pp. 397-405
    • Lake, R.A.1    Robinson, B.W.2
  • 20
    • 15944410592 scopus 로고    scopus 로고
    • Inhibition of CD4(+)25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide
    • 10.1182/blood-2004-06-2410 15591121
    • Lutsiak ME Semnani RT De Pascalis R Kashmiri SV Schlom J Sabzevari H Inhibition of CD4(+)25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide Blood 2005, 105:2862-2868. 10.1182/blood-2004-06-2410 15591121
    • (2005) Blood , vol.105 , pp. 2862-2868
    • Lutsiak, M.E.1    Semnani, R.T.2    De Pascalis, R.3    Kashmiri, S.V.4    Schlom, J.5    Sabzevari, H.6
  • 21
    • 0035328683 scopus 로고    scopus 로고
    • Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/macrophage-colony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerized mice
    • 11325840
    • Machiels JP Reilly RT Emens LA Ercolini AM Lei RY Weintraub D Okoye FI Jaffee EM Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/macrophage-colony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerized mice Cancer Res 2001, 61:3689-3697. 11325840
    • (2001) Cancer Res , vol.61 , pp. 3689-3697
    • Machiels, J.P.1    Reilly, R.T.2    Emens, L.A.3    Ercolini, A.M.4    Lei, R.Y.5    Weintraub, D.6    Okoye, F.I.7    Jaffee, E.M.8
  • 22
    • 33747888406 scopus 로고    scopus 로고
    • Efficacy of GM-CSF-producing tumor vaccine after docetaxel chemotherapy in mice bearing established Lewis lung carcinoma
    • 10.1097/01.cji.0000199198.43587.ba 16799332
    • Chu Y Wang LX Yang G Ross HJ Urba WJ Prell R Jooss K Xiong S Hu HM Efficacy of GM-CSF-producing tumor vaccine after docetaxel chemotherapy in mice bearing established Lewis lung carcinoma J Immunother 2006, 29:367-380. 10.1097/01.cji.0000199198.43587.ba 16799332
    • (2006) J Immunother , vol.29 , pp. 367-380
    • Chu, Y.1    Wang, L.X.2    Yang, G.3    Ross, H.J.4    Urba, W.J.5    Prell, R.6    Jooss, K.7    Xiong, S.8    Hu, H.M.9
  • 25
    • 23044445625 scopus 로고    scopus 로고
    • Cyclophosphamide decreases the number, percentage and the function of CD25+ CD4+ regulatory T cells, which suppress induction of contact hypersensitivity
    • 10.1016/j.jdermsci.2005.02.002 15899580
    • Ikezawa Y Nakazawa M Tamura C Takahashi K Minami M Ikezawa Z Cyclophosphamide decreases the number, percentage and the function of CD25+ CD4+ regulatory T cells, which suppress induction of contact hypersensitivity J Dermatol Sci 2005, 39:105-112. 10.1016/ j.jdermsci.2005.02.002 15899580
    • (2005) J Dermatol Sci , vol.39 , pp. 105-112
    • Ikezawa, Y.1    Nakazawa, M.2    Tamura, C.3    Takahashi, K.4    Minami, M.5    Ikezawa, Z.6
  • 28
    • 0020047427 scopus 로고
    • Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells
    • 10.1084/jem.155.4.1063 2186638 6460831
    • North RJ Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells J Exp Med 1982, 155:1063-1074. 10.1084/jem.155.4.1063 2186638 6460831
    • (1982) J Exp Med , vol.155 , pp. 1063-1074
    • North, R.J.1
  • 30
    • 35748975652 scopus 로고    scopus 로고
    • Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy
    • 10.1007/s00262-007-0336-x 17522861
    • Jordan JT Sun W Hussain SF DeAngulo G Prabhu SS Heimberger AB Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy Cancer Immunol Immunother 2008, 57:123-131. 10.1007/s00262-007-0336-x 17522861
    • (2008) Cancer Immunol Immunother , vol.57 , pp. 123-131
    • Jordan, J.T.1    Sun, W.2    Hussain, S.F.3    DeAngulo, G.4    Prabhu, S.S.5    Heimberger, A.B.6
  • 31
    • 0016314602 scopus 로고
    • Reversal of immunological tolerance by cyclophosphamide through inhibition of suppressor cell activity
    • 10.1038/249654a0 4275846
    • Polak L Turk JL Reversal of immunological tolerance by cyclophosphamide through inhibition of suppressor cell activity Nature 1974, 249:654-656. 10.1038/249654a0 4275846
    • (1974) Nature , vol.249 , pp. 654-656
    • Polak, L.1    Turk, J.L.2
  • 32
    • 0023930413 scopus 로고
    • Effect of low dose cyclophosphamide on the immune system of cancer patients: Depletion of CD4+, 2H4+ suppressor-inducer T-cells
    • 2830969
    • Berd D Mastrangelo MJ Effect of low dose cyclophosphamide on the immune system of cancer patients: Depletion of CD4+, 2H4+ suppressor-inducer T-cells Cancer Res 1988, 48:1671-1675. 2830969
    • (1988) Cancer Res , vol.48 , pp. 1671-1675
    • Berd, D.1    Mastrangelo, M.J.2
  • 33
    • 0042024964 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides potentiate the antitumor effects of chemotherapy or tumor resection in an orthotopic murine model of rhabdomyosarcoma
    • 12912962
    • Weigel BJ Rodeberg DA Krieg AM Blazar BR CpG oligodeoxynucleotides potentiate the antitumor effects of chemotherapy or tumor resection in an orthotopic murine model of rhabdomyosarcoma Clin Cancer Res 2003, 9:3105-3114. 12912962
    • (2003) Clin Cancer Res , vol.9 , pp. 3105-3114
    • Weigel, B.J.1    Rodeberg, D.A.2    Krieg, A.M.3    Blazar, B.R.4
  • 35
    • 34548570079 scopus 로고    scopus 로고
    • Leveraging the immune system during chemotherapy: Moving calreticulin to the cell surface converts apoptotic death from "silent" to immunogenic
    • 10.1158/0008-5472.CAN-07-1622 17804698
    • Obeid M Panaretakis T Tesniere A Joza N Tufi R Apetoh L Ghiringhelli F Zitvogel L Kroemer G Leveraging the immune system during chemotherapy: moving calreticulin to the cell surface converts apoptotic death from "silent" to immunogenic Cancer Res 2007, 67:7941-7944. 10.1158/ 0008-5472.CAN-07-1622 17804698
    • (2007) Cancer Res , vol.67 , pp. 7941-7944
    • Obeid, M.1    Panaretakis, T.2    Tesniere, A.3    Joza, N.4    Tufi, R.5    Apetoh, L.6    Ghiringhelli, F.7    Zitvogel, L.8    Kroemer, G.9
  • 36
    • 22244438547 scopus 로고    scopus 로고
    • Therapeutic synergism of gemcitabine and CpG-oligodeoxynucleotides in an orthotopic human pancreatic carcinoma xenograft
    • 10.1158/0008-5472.CAN-05-0602 16024642
    • Pratesi G Petrangolini G Tortoreto M Addis A Belluco S Rossini A Selleri S Rumio C Menard S Balsari A Therapeutic synergism of gemcitabine and CpG-oligodeoxynucleotides in an orthotopic human pancreatic carcinoma xenograft Cancer Res 2005, 65:6388-6393. 10.1158/0008-5472.CAN-05-0602 16024642
    • (2005) Cancer Res , vol.65 , pp. 6388-6393
    • Pratesi, G.1    Petrangolini, G.2    Tortoreto, M.3    Addis, A.4    Belluco, S.5    Rossini, A.6    Selleri, S.7    Rumio, C.8    Menard, S.9    Balsari, A.10
  • 37
    • 14844361299 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides inhibit tumor growth and reverse the immunosuppression caused by the therapy with 5-fluorouracil in murine hepatoma
    • 15754409
    • Wang XS Sheng Z Ruan YB Guang Y Yang ML CpG oligodeoxynucleotides inhibit tumor growth and reverse the immunosuppression caused by the therapy with 5-fluorouracil in murine hepatoma World J Gastroenterol 2005, 1: 1220-1224. 15754409
    • (2005) World J Gastroenterol , vol.11 , pp. 1220-1224
    • Wang, X.S.1    Sheng, Z.2    Ruan, Y.B.3    Guang, Y.4    Yang, M.L.5


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