Psychotropic drug-induced locomotor hyperactivity and prepulse inhibition regulation in male and female aromatase knockout (ArKO) mice: Role of dopamine D1 and D2 receptors and dopamine transporters

Psychopharmacology

Volumn 206, Issue 2, 2009, Pages 267-279

  Chavez, Carolina ^a,b   Gogos, Andrea ^a   Jones, Margaret E ^c   Van Den Buuse, Maarten ^a  

^a FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

Dopamine; Nucleus accumbens; Oestrogen; Schizophrenia

Indexed keywords

AMPHETAMINE; APOMORPHINE; AROMATASE; DIZOCILPINE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE TRANSPORTER; ESTROGEN; PHENCYCLIDINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG PROTEIN BINDING; DRUG RECEPTOR BINDING; FEMALE; GENOTYPE; HORMONE ACTION; HYPERACTIVITY; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; NUCLEUS ACCUMBENS; OPEN FIELD TEST; PATHOPHYSIOLOGY; PREPULSE INHIBITION; PRIORITY JOURNAL; PROTEIN FUNCTION; PUTAMEN; RECEPTOR DENSITY; SCHIZOPHRENIA; SEX DIFFERENCE; STARTLE REFLEX;

ACOUSTIC STIMULATION; ANIMALS; APOMORPHINE; AROMATASE; AUTORADIOGRAPHY; BEHAVIOR, ANIMAL; CAUDATE NUCLEUS; CROSS-OVER STUDIES; DIZOCILPINE MALEATE; DOPAMINE AGONISTS; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; EXCITATORY AMINO ACID ANTAGONISTS; HUMANS; HYPERKINESIS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR ACTIVITY; NEURAL INHIBITION; NUCLEUS ACCUMBENS; PHENCYCLIDINE; PROTEIN BINDING; PSYCHOACOUSTICS; PSYCHOTROPIC DRUGS; RANDOM ALLOCATION; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; SEX FACTORS; STARTLE REACTION; TIME FACTORS;

EID: 69549126141     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-009-1604-6     Document Type: Article

References (50)

1. B Adams B Moghaddam 1998 Corticolimbic dopamine neurotransmission is temporally dissociated from the cognitive and locomotor effects of phencyclidine J Neurosci 18 5545 5554
2. 2 dopamine receptor binding Brain Res 637 163 172
3. J Becker 1990 Direct effect of 17ß-estradiol on striatum: sex differences in dopamine release Synapse 5 157 164
4. JB Becker 1990 Estrogen rapidly potentiates amphetamine-induced striatal dopamine release and rotational behavior during microdialysis Neurosci Lett 118 169 171
5. JB Becker 1999 Gender differences in dopaminergic function in striatum and nucleus accumbens Pharmacol Biochem Behav 64 803 812
6. JB Becker H Molenda DL Hummer 2001 Gender differences in the behavioral responses to cocaine and amphetamine. Implications for mechanisms mediating gender differences in drug abuse Ann N Y Acad Sci 937 172 187
7. PP Bertrand UT Paranavitane C Chavez A Gogos M Jones M Van Den Buuse 2005 The effect of low estrogen state on serotonin transporter function in mouse hippocampus: a behavioral and electrochemical study Brain Res 1064 10 20
8. DL Braff MA Geyer GA Light J Sprock W Perry K Cadenhead NR Swerdlow 2001 Impact of prepulse characteristics on the detection of sensorimotor gating deficits in schizophrenia Schizophr Res 49 171 178
9. 3H]WIN 35,428) in the monkey brain Synapse 6 189 195
10. A Carlsson LO Hansson N Waters Ml Carlsson 1999 A glutamatergic deficiency model of schizophrenia Br J Psychiatry 174 2 6
11. D Castle P Sham R Murray 1998 Differences in distribution of ages of onset in males and females with schizophrenia Schizophr Res 33 179 183
12. KH Choy M Van Den Buuse 2008 Attenuated disruption of prepulse inhibition by dopaminergic stimulation after maternal deprivation and adolescent corticosterone treatment in rats Eur Neuropsychopharmacol 18 1 13
13. KHC Choy Y De Visser M Van Den Buuse 2008 The effect of 'two hit' neonatal and young-adult stress on dopaminergic modulation of prepulse inhibition and dopamine receptor density Br J Pharmacol 156 388 396
14. I Creese SD Iversen 1975 The pharmacological and anatomical substrates of the amphetamine response in the rat Brain Res 83 419 436
15. C Dalla K Antoniou Z Papadopoulou-Daifoti J Balthazart J Bakker 2004 Oestrogen-deficient female aromatase knockout (ArKO) mice exhibit depressive-like symptomatology Eur J Neurosci 20 217 228
16. CR Fisher KH Graves AF Parlow ER Simpson 1998 Characterization of mice deficient in aromatase (Arko) because of targeted disruption of the Cyp19 gene Proc Natl Acad Sci USA 95 6965 6970
17. ML Forgie J Stewart 1994 Sex differences in the locomotor-activating effects of amphetamine: role of circulating testosterone in adulthood Physiol Behav 55 639 644
18. MA Geyer A Markou 1995
19. MA Geyer K Krebs-Thomson DL Braff NR Swerdlow 2001 Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review Psychopharmacology 156 117 154
20. A Gogos S Martin ME Jones M Van Den Buuse 2006 Oestrogen modulation of the effect of 8-OH-DPAT on prepulse inhibition: effects of aromatase deficiency and castration in mice Psychopharmacology 188 100 110
21. 2A receptor antagonist, attenuates phencyclidine-induced fos expression in discrete regions of rat brain Eur J Pharmacol 417 189 194
22. H Häfner 2003 Gender differences in schizophrenia Psychoneuroendocrinology 28 17 54
23. RA Hill KJ Mcinnes ECH Gong MEE Jones ER Simpson WC Boon 2007 Estrogen deficient male mice develop compulsive behavior Biol Psychiatry 61 359 366
24. Re Hruska EK Silbergeld 1980 Estrogen treatment enhances dopamine receptor sensitivity in the rat striatum Eur J Pharmacol 61 397 400
25. KM Johnson SM Jones 1990 Neuropharmacology of phencyclidine: basic mechanisms and therapeutic potential Annu Rev Pharmacol Toxicol 30 707 750
26. MEE Jones AW Thorburn KL Britt KN Hewitt NG Wreford J Proietto OK Oz BJ Leury KM Robertson S Yao ER Simpson 2000 Aromatase-deficient (ArKO) mice have a phenotype of increased adiposity Proc Natl Acad Sci USA 97 12735 12740
27. PH Kelly 1975 Unilateral 6-hydroxydopamine lesions of nigrostriatal or mesolimbic dopamine-containing terminals and the drug-induced rotation of rats Brain Res 100 63 169
28. S Kusljic J Brosda TR Norman M Van Den Buuse 2005 Brain serotonin depletion by lesions of the median raphe nucleus enhances the psychotomimetic action of phencyclidine, but not dizocilpine (MK-801), in rats Brain Res 1049 217 226
29. CH Lammers UH D'Souza ZH Qin SH Lee S Yajima MM Mouradian 1999 Regulation of striatal dopamine receptors by corticosterone: an in vivo and in vitro study Mol Brain Res 69 281 285
30. M Laruelle A Abi-Dargham R Gil L Kegeles R Innis 1999 Increased dopamine transmission in schizophrenia: relationship to illness phases Biol Psychiatry 46 56 72
31. 2 receptors in rat striatum and nucleus accumbens Neuropharmacology 50 451 457
32. D Levesque T Di Paolo 1993 Modulation by estradiol and progesterone of the GTP effect on striatal D-2 dopamine receptors Biochem Pharmacol 45 723 733
33. R Makanjuola GW Ashcroft 1982 Behavioural effects of electrolytic and 6OHDA lesions of the accumbens and caudate-putamen nuclei Psychopharmacology 76 333 340
34. Mj Millan M Brocco A Gobert F Joly K Bervoets JM Rivet A Newman-Tancredi V Audinot S Maurel 1999 Contrasting mechanisms of action and sensitivity to antipsychotics of phencyclidine versus amphetamine: importance of nucleus accumbens 5-HT2A Sites For PCP-induced locomotion in the rat Eur J NeuroSci 11 4419 4432
35. SR Naik MR Kelkar UK Sheth 1978 Attenuation of stereotyped behaviour by sex steroids Psychopharmacology (Berl) 57 211 214
36. 2 dopamine receptor agonist disrupts sensorimotor gating in rats-implications for dopaminergic abnormalities in schizophrenia Neuropsychopharmacology 3 211 218
37. AJ Pijnenburg WM Honig JM Van Rossum 1975 Inhibition of d-amphetamine-induced locomotor activity by injection of haloperidol into the nucleus accumbens of the rat Psychopharmacologia 41 87 95
38. 4, receptor subtype is essential for the disruption of prepulse inhibition produced by amphetamine in mice J Neurosci 19 4627 4633
39. 2 receptor knock-out mice J Neurosci 22 9604 9611
40. 2 receptor agonists disrupt prepulse inhibition of startle in mice Neuropsychopharmacology 28 108 118
41. KM Robertson L O'donnell MEE Jones SJ Meachem WC Boon CR Fischer KH Graves RI Mclachlan ER Simpson 1999 Impairment of spermatogenesis in mice lacking a functional aromatase (Cyp 19) gene Proc Natl Acad Sci USA 96 7986 7991
42. U Scheffel C Steinert SE Kim MD Ehlers JW Boja MJ Kuhar 1996 Effect of dopaminergic drugs on the in vivo binding of [3h]WIN 35, 428 to central dopamine transporters Synapse 23 61 69
43. ER Simpson C Clyne G Rubin WC Boon K Robertson K Britt C Speed M Jones 2002 Aromatase-a brief overview Annu Rev Physiol 64 93 127
44. M Van Den Buuse ER Simpson ME Jones 2003 Prepulse inhibition of acoustic startle in aromatase knock-out mice: effects of age and gender Genes Brain Behav 2 93 102
45. M Van Den Buuse B Garner A Gogos S Kusljic 2005 Importance of animal models in schizophrenia research Aust NZ J Psychiatry 39 550 557
46. FJ Wan NR Swerdlow 1993 Intra-accumbens infusion of quinpirole impairs sensorimotor gating of acoustic startle in rats Psychopharmacology 113 103 109
47. GN Woodruff PH Kelly AO Elkhawad 1976 Effects of dopamine receptor stimulants on locomotor activity of rats with electrolytic or 6-hydroxydopamine-induced lesions of the nucleus accumbens Psychopharmacologia 47 195 198
48. L Xiao JB Becker 1998 Effects of estrogen agonists on amphetamine-stimulated striatal dopamine release Synapse 29 379 391
49. BK Yee H Russig J Feldon 2004 Apomorphine-induced prepulse inhibition disruption is associated with a paradoxical enhancement of prepulse stimulus reactivity Neuropsychopharmacology 29 240 248
50. W Zhou C Ka T Ml 2002 Estrogen regulation of gene expression in the brain: a possible mechanism altering the response to psychostimulants in female rats Brain Res Mol Brain Res 100 75 83