Brain serotonin depletion by lesions of the median raphe nucleus enhances the psychotomimetic action of phencyclidine, but not dizocilpine (MK-801), in rats

Brain Research

Volumn 1049, Issue 2, 2005, Pages 217-226

  Kusljic, Snezana ^a,b   Brosda, Jan ^a   Norman, Trevor R ^b   Van Den Buuse, Maarten ^a,b  

^a FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Locomotor activity; MK 801; Phencyclidine; Schizophrenia; Serotonin

Indexed keywords

5,7 DIHYDROXYTRYPTAMINE; DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROTOXIN; PHENCYCLIDINE; PSYCHEDELIC AGENT; SEROTONIN; SEROTONIN AGONIST; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN INJURY; BRAIN REGION; COMPARATIVE STUDY; CONTROLLED STUDY; CORPUS STRIATUM; DORSAL RAPHE NUCLEUS; FRONTAL CORTEX; HIPPOCAMPUS; HYPERACTIVITY; LOCOMOTION; MALE; MEDIAN RAPHE NUCLEUS; MICROINJECTION; NERVE PROJECTION; NONHUMAN; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RAT; REARING; REGULATORY MECHANISM; SCHIZOPHRENIA; SEROTONIN BRAIN LEVEL; SEROTONIN RELEASE; STEREOTYPY;

5,7-DIHYDROXYTRYPTAMINE; ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; BRAIN; BRAIN CHEMISTRY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIZOCILPINE MALEATE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; EXCITATORY AMINO ACID ANTAGONISTS; HYPERKINESIS; MALE; MOTOR ACTIVITY; PHENCYCLIDINE; RAPHE NUCLEI; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN; SEROTONIN AGENTS; TIME FACTORS;

EID: 23044440159     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2005.05.017     Document Type: Article

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