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Volumn 41, Issue 3, 2009, Pages 332-338

Critical role of serum response factor in pulmonary myofibroblast differentiation induced by TGF-β

Author keywords

Myofibroblast; Protein kinase A; Serum response factor; Smad; Transforming growth factor

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; HYBRID PROTEIN; ILOPROST; SERUM RESPONSE FACTOR; SHORT HAIRPIN RNA; SMAD1 PROTEIN; TRANSFORMING GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA;

EID: 69449104522     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2008-0288OC     Document Type: Article
Times cited : (93)

References (50)
  • 1
    • 2142646426 scopus 로고    scopus 로고
    • TGF-beta signaling and the fibrotic response
    • Leask A, Abraham DJ. TGF-beta signaling and the fibrotic response. FASEB J 2004;18:816-827.
    • (2004) FASEB J , vol.18 , pp. 816-827
    • Leask, A.1    Abraham, D.J.2
  • 2
    • 0041827227 scopus 로고    scopus 로고
    • Fibroblast phenotypes in pulmonary fibrosis
    • Phan SH. Fibroblast phenotypes in pulmonary fibrosis. Am J Respir Cell Mol Biol 2003;29:S87-S92.
    • (2003) Am J Respir Cell Mol Biol , vol.29
    • Phan, S.H.1
  • 5
    • 0026010305 scopus 로고
    • Transforming growth factor beta 1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis
    • Broekelmann TJ, Limper AH, Colby TV, McDonald JA. Transforming growth factor beta 1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis. Proc Natl Acad Sci USA 1991;88:6642-6646.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 6642-6646
    • Broekelmann, T.J.1    Limper, A.H.2    Colby, T.V.3    McDonald, J.A.4
  • 6
    • 34147099468 scopus 로고    scopus 로고
    • Transforming growth factor (TGF)-beta1 stimulates pulmonary fibrosis and inflammation via a bax-dependent, bid-activated pathway that involves matrix metalloproteinase-12
    • Kang HR, Cho SJ, Lee CG, Homer RJ, Elias JA. Transforming growth factor (TGF)-beta1 stimulates pulmonary fibrosis and inflammation via a bax-dependent, bid-activated pathway that involves matrix metalloproteinase-12. J Biol Chem 2007;282:7723-7732.
    • (2007) J Biol Chem , vol.282 , pp. 7723-7732
    • Kang, H.R.1    Cho, S.J.2    Lee, C.G.3    Homer, R.J.4    Elias, J.A.5
  • 7
    • 0029337807 scopus 로고
    • Increased expression of transforming growth factor beta isoforms (beta 1, beta 2, beta 3) in bleomycin-induced pulmonary fibrosis
    • Santana A, Saxena B, Noble NA, Gold LI, Marshall BC. Increased expression of transforming growth factor beta isoforms (beta 1, beta 2, beta 3) in bleomycin-induced pulmonary fibrosis. Am J Respir Cell Mol Biol 1995;13:34-44.
    • (1995) Am J Respir Cell Mol Biol , vol.13 , pp. 34-44
    • Santana, A.1    Saxena, B.2    Noble, N.A.3    Gold, L.I.4    Marshall, B.C.5
  • 8
    • 0026597574 scopus 로고
    • Lung cytokine production in bleomycin-induced pulmonary fibrosis
    • Phan SH, Kunkel SL. Lung cytokine production in bleomycin-induced pulmonary fibrosis. Exp Lung Res 1992;18:29-43.
    • (1992) Exp Lung Res , vol.18 , pp. 29-43
    • Phan, S.H.1    Kunkel, S.L.2
  • 9
    • 23044466047 scopus 로고    scopus 로고
    • Specificity and versatility in TGF-beta signaling through smads
    • DOI 10.1146/annurev.cellbio.21.022404.142018
    • Feng XH, Derynck R. Specificity and versatility in TGF-beta signaling through Smads. Annu Rev Cell Dev Biol 2005;21:659-693. (Pubitemid 41740650)
    • (2005) Annual Review of Cell and Developmental Biology , vol.21 , pp. 659-693
    • Feng, X.-H.1    Derynck, R.2
  • 10
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad-independent pathways in TGF-beta family signalling
    • DOI 10.1038/nature02006
    • Derynck R, Zhang YE. Smad-dependent and smad-independent pathways in TGF-beta family signalling. Nature 2003;425:577-584. (Pubitemid 37280136)
    • (2003) Nature , vol.425 , Issue.6958 , pp. 577-584
    • Derynck, R.1    Zhang, Y.E.2
  • 11
    • 4644308155 scopus 로고    scopus 로고
    • Induction of vascular smooth muscle alpha-actin gene transcription in transforming growth factor beta1-activated myofibroblasts mediated by dynamic interplay between the pur repressor proteins and sp1/smad coactivators
    • Subramanian SV, Polikandriotis JA, Kelm RJ Jr, David JJ, Orosz CG, Strauch AR. Induction of vascular smooth muscle alpha-actin gene transcription in transforming growth factor beta1-activated myofibroblasts mediated by dynamic interplay between the pur repressor proteins and sp1/smad coactivators. Mol Biol Cell 2004;15:4532-4543.
    • (2004) Mol Biol Cell , vol.15 , pp. 4532-4543
    • Subramanian, S.V.1    Polikandriotis, J.A.2    Kelm Jr., R.J.3    David, J.J.4    Orosz, C.G.5    Strauch, A.R.6
  • 12
    • 0344924879 scopus 로고    scopus 로고
    • Interaction of Smad3 and SRF-associated complex mediates TGF-beta1 signals to regulate SM22 transcription during myofibroblast differentiation
    • DOI 10.1016/j.yjmcc.2003.09.002
    • Qiu P, Feng XH, Li L. Interaction of smad3 and srf-associated complex mediates TGF-beta1 signals to regulate sm22 transcription during myofibroblast differentiation. J Mol Cell Cardiol 2003;35:1407-1420. (Pubitemid 37491184)
    • (2003) Journal of Molecular and Cellular Cardiology , vol.35 , Issue.12 , pp. 1407-1420
    • Qiu, P.1    Feng, X.-H.2    Li, L.3
  • 13
    • 0042831330 scopus 로고    scopus 로고
    • Smad3 mediates transforming growth factor-beta-induced alpha-smooth muscle actin expression
    • DOI 10.1165/rcmb.2003-0063OC
    • Hu B, Wu Z, Phan SH. Smad3 mediates transforming growth factor-beta-induced alpha-smooth muscle actin expression. Am J Respir Cell Mol Biol 2003;29:397-404. (Pubitemid 37093999)
    • (2003) American Journal of Respiratory Cell and Molecular Biology , vol.29 , Issue.3 I , pp. 397-404
    • Hu, B.1    Wu, Z.2    Phan, S.H.3
  • 14
    • 0034532401 scopus 로고    scopus 로고
    • Positive- And negative-acting kruppel-like transcription factors bind a transforming growth factor beta control element required for expression of the smooth muscle cell differentiation marker sm22alpha in vivo
    • Adam PJ, Regan CP, Hautmann MB, Owens GK. Positive- and negative-acting kruppel-like transcription factors bind a transforming growth factor beta control element required for expression of the smooth muscle cell differentiation marker sm22alpha in vivo. J Biol Chem 2000;275:37798-37806.
    • (2000) J Biol Chem , vol.275 , pp. 37798-37806
    • Adam, P.J.1    Regan, C.P.2    Hautmann, M.B.3    Owens, G.K.4
  • 16
    • 0037183986 scopus 로고    scopus 로고
    • Vascular smooth muscle alpha-actin gene transcription during myofibroblast differentiation requires sp1/3 protein binding proximal to the mcat enhancer
    • Cogan JG, Subramanian SV, Polikandriotis JA, Kelm RJ Jr, Strauch AR. Vascular smooth muscle alpha-actin gene transcription during myofibroblast differentiation requires sp1/3 protein binding proximal to the mcat enhancer. J Biol Chem 2002;277:36433-36442.
    • (2002) J Biol Chem , vol.277 , pp. 36433-36442
    • Cogan, J.G.1    Subramanian, S.V.2    Polikandriotis, J.A.3    Kelm Jr., R.J.4    Strauch, A.R.5
  • 17
    • 34547647436 scopus 로고    scopus 로고
    • PGE(2) inhibition of TGF-beta1-induced myofibroblast differentiation is smad-independent but involves cell shape and adhesion-dependent signaling
    • Thomas PE, Peters-Golden M, White ES, Thannickal VJ, Moore BB. PGE(2) inhibition of TGF-beta1-induced myofibroblast differentiation is smad-independent but involves cell shape and adhesion-dependent signaling. Am J Physiol Lung Cell Mol Physiol 2007;293: L417-L428.
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.293
    • Thomas, P.E.1    Peters-Golden, M.2    White, E.S.3    Thannickal, V.J.4    Moore, B.B.5
  • 19
    • 0037870478 scopus 로고    scopus 로고
    • Serum response factor: Toggling between disparate programs of gene expression
    • Miano JM. Serum response factor: toggling between disparate programs of gene expression. J Mol Cell Cardiol 2003;35:577-593.
    • (2003) J Mol Cell Cardiol , vol.35 , pp. 577-593
    • Miano, J.M.1
  • 20
    • 0032538570 scopus 로고    scopus 로고
    • Specific involvement of G proteins in regulation of serum response factor-mediated gene transcription by different receptors
    • DOI 10.1074/jbc.273.42.27118
    • Mao J, Yuan H, Xie W, Simon MI, Wu D. Specific involvement of G proteins in regulation of serum response factor-mediated gene transcription by different receptors. J Biol Chem 1998;273:27118-27123. (Pubitemid 28500418)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.42 , pp. 27118-27123
    • Mao, J.1    Yuan, H.2    Xie, W.3    Simon, M.I.4    Wu, D.5
  • 21
    • 0037409295 scopus 로고    scopus 로고
    • Functional significance of protein kinase a activation by endothelin-1 and ATP: Negative regulation of SRF-dependent gene expression by PKA
    • DOI 10.1016/S0898-6568(02)00148-1
    • Davis A, Hogarth K, Fernandes D, Solway J, Niu J, Kolenko V, Browning D, Miano JM, Orlov SN, Dulin NO. Functional significance of protein kinase a activation by endothelin-1 and ATP: negative regulation of srf-dependent gene expression by PKA. Cell Signal 2003;15:597-604. (Pubitemid 36385165)
    • (2003) Cellular Signalling , vol.15 , Issue.6 , pp. 597-604
    • Davis, A.1    Hogarth, K.2    Fernandes, D.3    Solway, J.4    Niu, J.5    Kolenko, V.6    Browning, D.7    Miano, J.M.8    Orlov, S.N.9    Dulin, N.O.10
  • 22
    • 0035014034 scopus 로고    scopus 로고
    • Regulation of alpha-smooth muscle actin gene expression in myofibroblast differentiation from rat lung fibroblasts
    • DOI 10.1016/S1357-2725(01)00041-3, PII S1357272501000413
    • Roy SG, Nozaki Y, Phan SH. Regulation of alpha-smooth muscle actin gene expression in myofibroblast differentiation from rat lung fibroblasts. Int J Biochem Cell Biol 2001;33:723-734. (Pubitemid 32520968)
    • (2001) International Journal of Biochemistry and Cell Biology , vol.33 , Issue.7 , pp. 723-734
    • Roy, S.G.1    Nozaki, Y.2    Phan, S.H.3
  • 23
    • 0032847679 scopus 로고    scopus 로고
    • Similarities and differences in smooth muscle alpha-actin induction by TGF-beta in smooth muscle versus non-smooth muscle cells
    • Hautmann MB, Adam PJ, Owens GK. Similarities and differences in smooth muscle alpha-actin induction by TGF-beta in smooth muscle versus non-smooth muscle cells. Arterioscler Thromb Vasc Biol 1999; 19:2049-2058.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 2049-2058
    • Hautmann, M.B.1    Adam, P.J.2    Owens, G.K.3
  • 25
    • 0026744318 scopus 로고
    • Human and drosophila homeodomain proteins that enhance the DNA-binding activity of serum response factor
    • Grueneberg DA, Natesan S, Alexandre C, Gilman MZ. Human and drosophila homeodomain proteins that enhance the DNA-binding activity of serum response factor. Science 1992;257:1089-1095.
    • (1992) Science , vol.257 , pp. 1089-1095
    • Grueneberg, D.A.1    Natesan, S.2    Alexandre, C.3    Gilman, M.Z.4
  • 27
    • 14944366939 scopus 로고    scopus 로고
    • Regulation of serum response factor-dependent gene expression by proteasome inhibitors
    • DOI 10.1124/mol.104.006874
    • Sandbo N, Qin Y, Taurin S, Hogarth DK, Kreutz B, Dulin NO. Regulation of serum response factor-dependent gene expression by proteasome inhibitors. Mol Pharmacol 2005;67:789-797. (Pubitemid 40365326)
    • (2005) Molecular Pharmacology , vol.67 , Issue.3 , pp. 789-797
    • Sandbo, N.1    Qin, Y.2    Taurin, S.3    Hogarth, D.K.4    Kreutz, B.5    Dulin, N.O.6
  • 28
    • 34047105740 scopus 로고    scopus 로고
    • Downregulation of smooth muscle alpha-actin expression by bacterial lipopolysaccharide
    • DOI 10.1016/j.cardiores.2007.01.011, PII S0008636307000181
    • Sandbo N, Taurin S, Yau DM, Kregel S, Mitchell R, Dulin NO. Downregulation of smooth muscle alpha-actin expression by bacterial lipopolysaccharide. Cardiovasc Res 2007;74:262-269. (Pubitemid 46517509)
    • (2007) Cardiovascular Research , vol.74 , Issue.2 , pp. 262-269
    • Sandbo, N.1    Taurin, S.2    Yau, D.M.3    Kregel, S.4    Mitchell, R.5    Dulin, N.O.6
  • 31
    • 0029895008 scopus 로고    scopus 로고
    • Expression of the serum response factor gene is regulated by serum response factor binding sites
    • DOI 10.1074/jbc.271.28.16535
    • Spencer JA, Misra RP. Expression of the serum response factor gene is regulated by serum response factor binding sites. J Biol Chem 1996; 271:16535-16543. (Pubitemid 26239007)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.28 , pp. 16535-16543
    • Spencer, J.A.1    Misra, R.P.2
  • 32
    • 0033518111 scopus 로고    scopus 로고
    • Expression of the srf gene occurs through a ras/sp/srf-mediated-mechanism in response to serum growth signals
    • Spencer JA, Misra RP. Expression of the srf gene occurs through a ras/sp/srf-mediated-mechanism in response to serum growth signals. Oncogene 1999;18:7319-7327.
    • (1999) Oncogene , vol.18 , pp. 7319-7327
    • Spencer, J.A.1    Misra, R.P.2
  • 33
    • 0028303913 scopus 로고
    • CAMP- And cGMP-dependent protein kinase phosphorylation sites of the focal adhesion vasodilator-stimulated phosphoprotein (VASP) in vitro and in intact human platelets
    • Butt E, Abel K, Krieger M, Palm D, Hoppe V, Hoppe J, Walter U. CAMP- and CGMP-dependent protein kinase phosphorylation sites of the focal adhesion vasodilator-stimulated phosphoprotein (VASP) in vitro and in intact human platelets. J Biol Chem 1994;269:14509-14517. (Pubitemid 24194005)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.20 , pp. 14509-14517
    • Butt, E.1    Abel, K.2    Krieger, M.3    Palm, D.4    Hoppe, V.5    Hoppe, J.6    Walter, U.7
  • 35
  • 36
    • 0025742603 scopus 로고
    • The serum response factor is extensively modified by phosphorylation following its synthesis in serum-stimulated fibroblasts
    • Misra RP, Rivera VM, Wang JM, Fan PD, Greenberg ME. The serum response factor is extensively modified by phosphorylation following its synthesis in serum-stimulated fibroblasts. Mol Cell Biol 1991;11: 4545-4554.
    • (1991) Mol Cell Biol , vol.11 , pp. 4545-4554
    • Misra, R.P.1    Rivera, V.M.2    Wang, J.M.3    Fan, P.D.4    Greenberg, M.E.5
  • 37
    • 0038737042 scopus 로고    scopus 로고
    • Actin dynamics control SRF activity by regulation of its coactivator MAL
    • DOI 10.1016/S0092-8674(03)00278-2
    • Miralles F, Posern G, Zaromytidou AI, Treisman R. Actin dynamics control srf activity by regulation of its coactivator mal. Cell 2003;113: 329-342. (Pubitemid 36556115)
    • (2003) Cell , vol.113 , Issue.3 , pp. 329-342
    • Miralles, F.1    Posern, G.2    Zaromytidou, A.-I.3    Treisman, R.4
  • 38
    • 0033597825 scopus 로고    scopus 로고
    • Signal-regulated activation of serum response factor is mediated by changes in actin dynamics
    • DOI 10.1016/S0092-8674(00)81011-9
    • Sotiropoulos A, Gineitis D, Copeland J, Treisman R. Signal-regulated activation of serum response factor is mediated by changes in actin dynamics. Cell 1999;98:159-169. (Pubitemid 29344904)
    • (1999) Cell , vol.98 , Issue.2 , pp. 159-169
    • Sotiropoulos, A.1    Gineitis, D.2    Copeland, J.3    Treisman, R.4
  • 39
    • 0029015774 scopus 로고
    • The rho family GTPases rhoa, rac1, and cdc42hs regulate transcriptional activation by srf
    • Hill CS, Wynne J, Treisman R. The rho family GTPases rhoa, rac1, and cdc42hs regulate transcriptional activation by srf. Cell 1995;81:1159-1170.
    • (1995) Cell , vol.81 , pp. 1159-1170
    • Hill, C.S.1    Wynne, J.2    Treisman, R.3
  • 41
    • 5644293131 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate stimulates smooth muscle cell differentiation and proliferation by activating separate serum response factor co-factors
    • DOI 10.1074/jbc.M405432200
    • Lockman K, Hinson JS, Medlin MD, Morris D, Taylor JM, Mack CP. Sphingosine 1-phosphate stimulates smooth muscle cell differentiation and proliferation by activating separate serum response factor co-factors. J Biol Chem 2004;279:42422-42430. (Pubitemid 39372124)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.41 , pp. 42422-42430
    • Lockman, K.1    Hinson, J.S.2    Medlin, M.D.3    Morris, D.4    Taylor, J.M.5    Mack, C.P.6
  • 43
    • 0030040750 scopus 로고    scopus 로고
    • Protein kinase a phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes
    • Lang P, Gesbert F, Delespine-Carmagnat M, Stancou R, Pouchelet M, Bertoglio J. Protein kinase A phosphorylation of rhoa mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes. EMBO J 1996;15:510-519. (Pubitemid 26044564)
    • (1996) EMBO Journal , vol.15 , Issue.3 , pp. 510-519
    • Lang, P.1    Gesbert, F.2    Delespine-Carmagnat, M.3    Stancou, R.4    Pouchelet, M.5    Bertoglio, J.6
  • 44
    • 0037048683 scopus 로고    scopus 로고
    • The vasodilator-stimulated phosphoprotein promotes actin polymerisation through direct binding to monomeric actin
    • Walders-Harbeck B, Khaitlina SY, Hinssen H, Jockusch BM, Illenberger S. The vasodilator-stimulated phosphoprotein promotes actin polymerisation through direct binding to monomeric actin. FEBS Lett 2002;529: 275-280.
    • (2002) FEBS Lett , vol.529 , pp. 275-280
    • Walders-Harbeck, B.1    Khaitlina, S.Y.2    Hinssen, H.3    Jockusch, B.M.4    Illenberger, S.5
  • 46
    • 0028988488 scopus 로고
    • The serum response factor nuclear localization signal: General implications for cyclic AMP-dependent protein kinase activity in control of nuclear translocation
    • Gauthier-Rouviere C, Vandromme M, Lautredou N, Cai QQ, Girard F, Fernandez A, Lamb N. The serum response factor nuclear localization signal: general implications for cyclic AMP-dependent protein kinase activity in control of nuclear translocation. Mol Cell Biol 1995; 15:433-444. (Pubitemid 24379942)
    • (1995) Molecular and Cellular Biology , vol.15 , Issue.1 , pp. 433-444
    • Gauthier-rouviere, C.1    Vandromme, M.2    Lautredou, N.3    Cai, Q.Q.4    Girard, F.5    Fernandez, A.6    Lamb, N.7
  • 50
    • 53449089229 scopus 로고    scopus 로고
    • Prostaglandin E2 inhibits specific lung fibroblast functions via selective actions of PKA and EPAC-1
    • Huang SK, Wettlaufer SH, Chung J, Peters-Golden M. Prostaglandin E2 inhibits specific lung fibroblast functions via selective actions of PKA and EPAC-1. Am J Respir Cell Mol Biol 2008;39:482-489.
    • (2008) Am J Respir Cell Mol Biol , vol.39 , pp. 482-489
    • Huang, S.K.1    Wettlaufer, S.H.2    Chung, J.3    Peters-Golden, M.4


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