A novel benzodiazepine increases the sensitivity of B cells to receptor stimulation with synergistic effects on calcium signaling and apoptosis

Journal of Biological Chemistry

Volumn 279, Issue 28, 2004, Pages 29615-29621

  Bednarski, Jeffrey J ^a   Lyssiotis, Costas A ^a   Roush, Rebecca ^a   Boitano, Anthony E ^a   Glick, Gary D ^a   Opipari Jr , Anthony W ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; CALCIUM; CELLS; DISEASES; DRUG PRODUCTS;

ANTI LUPUS-AGENTS; THERAPEUTIC ACTIVITY;

BIOCHEMISTRY;

B LYMPHOCYTE RECEPTOR; BENZODIAZEPINE DERIVATIVE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; BROMOCALCIMYCIN; BZ 423; CALCIUM ION; CD40 ANTIGEN; CYCLOHEXIMIDE; CYCLOSPORIN A; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; IMMUNOGLOBULIN M ANTIBODY; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; B LYMPHOCYTE ACTIVATION; CALCIUM SIGNALING; CELL DEATH; DRUG POTENTIATION; FEMALE; GERMINAL CENTER; IMMUNOMODULATION; LYMPHOCYTOTOXICITY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SPLEEN CELL; SYSTEMIC LUPUS ERYTHEMATOSUS;

ANIMALS; APOPTOSIS; B-LYMPHOCYTES; BENZODIAZEPINES; CALCIUM; CALCIUM SIGNALING; CELLS, CULTURED; CHELATING AGENTS; DISEASE MODELS, ANIMAL; EGTAZIC ACID; FEMALE; FLUORESCENT DYES; GERMINAL CENTER; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MOLECULAR STRUCTURE; RECEPTORS, ANTIGEN, B-CELL; SUPEROXIDES;

ANIMALIA;

EID: 3142777968     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M403507200     Document Type: Article

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