Serine protease inhibitor (SERPIN) B1 promotes oral cancer cell motility and is over-expressed in invasive oral squamous cell carcinoma

Oral Oncology

Volumn 45, Issue 9, 2009, Pages 771-776

  Tseng, Mei Yu ^a   Liu, Shyun Yeu ^b,c   Chen, Hau Ren ^d   Wu, Yu Jen ^e   Chiu, Chien Chih ^a   Chan, Po Ting ^a   Chiang, Wei Fan ^b   Liu, Yu Chi ^f   Lu, Chien Yu ^g   Jou, Yuh Shan ^h   Chen, Jeff Yi Fu ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b CHI MEI MEDICAL CENTER   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d NATIONAL CHUNG CHENG UNIVERSITY   (Taiwan)

^e MEIHO UNIVERSITY   (Taiwan)

^f TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^g KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^h INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

Author keywords

Invasive oral squamous cell carcinoma; Metastases; Motility; Oral cancer; SERPINB1

Indexed keywords

MESSENGER RNA; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR CLADE B MEMBER1 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CANCER TISSUE; CELL DIFFERENTIATION; CELL MIGRATION; CELL MOTILITY; COMPARATIVE STUDY; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INVASIVE CARCINOMA; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOUTH CARCINOMA; MOUTH MUCOSA; PATHOLOGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEOMICS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA; TWO DIMENSIONAL ELECTROPHORESIS; WESTERN BLOTTING;

CARCINOMA, SQUAMOUS CELL; CASE-CONTROL STUDIES; CELL LINE, TUMOR; CELL MOVEMENT; HUMANS; MOUTH MUCOSA; MOUTH NEOPLASMS; NEOPLASM PROTEINS; PROTEOME; SERPINS;

EID: 69249236955     PISSN: 13688375     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2008.11.013     Document Type: Article

References (33)

1. Irving J.A., Pike R.N., Lesk A.M., and Whisstock J.C. Phylogeny of the serpin superfamily: implications of patterns of amino acid conservation for structure and function. Genome Res 10 (2000) 1845-1864
2. Rawlings N.D., Tolle D.P., and Barrett A.J. Evolutionary families of peptidase inhibitors. Biochem J 378 (2004) 705-716
3. Stein P.E., Leslie A.G., Finch J.T., Turnell W.G., McLaughlin P.J., and Carrell R.W. Crystal structure of ovalbumin as a model for the reactive centre of serpins. Nature 347 (1990) 99-102
4. Stein P.E., and Carrell R.W. What do dysfunctional serpins tell us about molecular mobility and disease?. Nat Struct Biol 2 (1995) 96-113
5. Komiyama T., Ray C.A., Pickup D.J., Howard A.D., Thornberry N.A., Peterson E.P., et al. Inhibition of interleukin-1 beta converting enzyme by the cowpox virus serpin CrmA. An example of cross-class inhibition. J Biol Chem 269 (1994) 19331-19337
6. Schick C., Pemberton P.A., Shi G.P., Kamachi Y., Cataltepe S., Bartuski A.J., et al. Cross-class inhibition of the cysteine proteinases cathepsins K, L, and S by the serpin squamous cell carcinoma antigen 1: a kinetic analysis. Biochemistry 37 (1998) 5258-5266
7. Silverman G.A., Bird P.I., Carrell R.W., Church F.C., Coughlin P.B., Gettins P.G., et al. The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature. J Biol Chem 276 (2001) 33293-33296
8. Pemberton P.A., Stein P.E., Pepys M.B., Potter J.M., and Carrell R.W. Hormone binding globulins undergo serpin conformational change in inflammation. Nature 336 (1988) 257-258
9. Nagata K. Hsp47: a collagen-specific molecular chaperone. Trends Biochem Sci 21 (1996) 22-26
10. Potempa J., Korzus E., and Travis J. The serpin superfamily of proteinase inhibitors: structure, function, and regulation. J Biol Chem 269 (1994) 15957-15960
11. Lomas D.A., Evans D.L., Finch J.T., and Carrell R.W. The mechanism of Z alpha 1-antitrypsin accumulation in the liver. Nature 357 (1992) 605-607
12. Bruce D., Perry D.J., Borg J.Y., Carrell R.W., and Wardell M.R. Thromboembolic disease due to thermolabile conformational changes of antithrombin Rouen-VI (187 Asn -->Asp). J Clin Invest 94 (1994) 2265-2274
13. Silverman G.A., Whisstock J.C., Askew D.J., Pak S.C., Luke C.J., Cataltepe S., et al. Human clade B serpins (ov-serpins) belong to a cohort of evolutionarily dispersed intracellular proteinase inhibitor clades that protect cells from promiscuous proteolysis. Cell Mol Life Sci 61 (2004) 301-325
14. Zou Z., Anisowicz A., Hendrix M.J., Thor A., Neveu M., Sheng S., et al. Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells. Science 263 (1994) 526-529
15. Luo J.L., Tan W., Ricono J.M., Korchynskyi O., Zhang M., Gonias S.L., et al. Nuclear cytokine-activated IKKalpha controls prostate cancer metastasis by repressing Maspin. Nature 446 (2007) 690-694
16. Woolgar J.A., Scott J., Vaughan E.D., Brown J.S., West C.R., and Rogers S. Survival, metastasis and recurrence of oral cancer in relation to pathological features. Ann R Coll Surg Engl 77 (1995) 325-331
17. Nagata M., Fujita H., Ida H., Hoshina H., Inoue T., Seki Y., et al. Identification of potential biomarkers of lymph node metastasis in oral squamous cell carcinoma by cDNA microarray analysis. Int J Cancer 106 (2003) 683-689
18. Nguyen S.T., Hasegawa S., Tsuda H., Tomioka H., Ushijima M., Noda M., et al. Identification of a predictive gene expression signature of cervical lymph node metastasis in oral squamous cell carcinoma. Cancer Sci 98 (2007) 740-746
19. O'Donnell R.K., Kupferman M., Wei S.J., Singhal S., Weber R., O'Malley B., et al. Gene expression signature predicts lymphatic metastasis in squamous cell carcinoma of the oral cavity. Oncogene 24 (2005) 1244-1251
20. Koike H., Uzawa K., Nakashima D., Shimada K., Kato Y., Higo M., et al. Identification of differentially expressed proteins in oral squamous cell carcinoma using a global proteomic approach. Int J Oncol 27 (2005) 59-67
21. Lo W.Y., Tsai M.H., Tsai Y., Hua C.H., Tsai F.J., Huang S.Y., et al. Identification of over-expressed proteins in oral squamous cell carcinoma (OSCC) patients by clinical proteomic analysis. Clin Chim Acta 376 (2007) 101-107
22. Turhani D., Krapfenbauer K., Thurnher D., Langen H., and Fountoulakis M. Identification of differentially expressed, tumor-associated proteins in oral squamous cell carcinoma by proteomic analysis. Electrophoresis 27 (2006) 1417-1423
23. Wang Z., Jiang L., Huang C., Li Z., Chen L., Gou L., et al. Comparative proteomic approach to screening of potential diagnostic and therapeutic targets for oral squamous cell carcinoma. Mol Cell Proteomics (2008)
24. Tantipaiboonwong P., Sinchaikul S., Sriyam S., Phutrakul S., and Chen S.T. Different techniques for urinary protein analysis of normal and lung cancer patients. Proteomics 5 (2005) 1140-1149
25. Chen J.Y., Chang Y.L., Yu Y.C., Chao C.C., Kao H.W., Wu C.T., et al. Specific induction of the high-molecular-weight microtubule-associated protein 2 (hmw-MAP2) by betel quid extract in cultured oral keratinocytes: clinical implications in betel quid-associated oral squamous cell carcinoma (OSCC). Carcinogenesis 25 (2004) 269-276
26. Liu S.Y., Chen Y.T., Tseng M.Y., Hung C.C., Chiang W.F., Chen H.R., et al. Involvement of microtubule-associated protein 2 (MAP2) in oral cancer cell motility: a novel biological function of MAP2 in non-neuronal cells. Biochem Biophys Res Commun 366 (2008) 520-525
27. Reeves E.P., Lu H., Jacobs H.L., Messina C.G., Bolsover S., Gabella G., et al. Killing activity of neutrophils is mediated through activation of proteases by K+ flux. Nature 416 (2002) 291-297
28. Birrer P. Proteases and antiproteases in cystic fibrosis: pathogenetic considerations and therapeutic strategies. Respiration 62 Suppl. 1 (1995) 25-28
29. Rees D.D., and Brain J.D. Effects of cystic fibrosis airway secretions on rat lung: role of neutrophil elastase. Am J Physiol 269 (1995) L195-202
30. Wang L., Zhu J.S., Song M.Q., Chen G.Q., and Chen J.L. Comparison of gene expression profiles between primary tumor and metastatic lesions in gastric cancer patients using laser microdissection and cDNA microarray. World J Gastroenterol 12 (2006) 6949-6954
31. Ashcroft G.S., Lei K., Jin W., Longenecker G., Kulkarni A.B., Greenwell-Wild T., et al. Secretory leukocyte protease inhibitor mediates non-redundant functions necessary for normal wound healing. Nat Med 6 (2000) 1147-1153
32. Wolf K., Mazo I., Leung H., Engelke K., von Andrian U.H., Deryugina E.I., et al. Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis. J Cell Biol 160 (2003) 267-277
33. Chen C.S., Tsai K.Y., and Hong D.J. Influence of the size and metastasis of cervical lymph nodes on the survival of oral cancer patients. Chin J Dent 1 (2005) 25-31