Involvement of microtubule-associated protein 2 (MAP2) in oral cancer cell motility: A novel biological function of MAP2 in non-neuronal cells

Biochemical and Biophysical Research Communications

Volumn 366, Issue 2, 2008, Pages 520-525

  Liu, Shyun Yeu ^a   Chen, Yi Ting ^b   Tseng, Mei Yu ^c   Hung, Chih Chang ^d   Chiang, Wei Fan ^a   Chen, Hau Ren ^e   Shieh, Tien Yu ^c   Chen, Chung Ho ^c   Jou, Yuh Shan ^f   Chen, Jeff Yi Fu ^c  

^a CHI MEI MEDICAL CENTER   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^d NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^e NATIONAL CHUNG CHENG UNIVERSITY   (Taiwan)

^f INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

Author keywords

Cell migration; Invasive oral cancer tissues; Microtubule bundling; Microtubule associated protein 2 (MAP2); Oral cancer cells

Indexed keywords

MICROTUBULE ASSOCIATED PROTEIN 2; SMALL INTERFERING RNA;

ARTICLE; BIOLOGICAL ACTIVITY; CANCER INVASION; CANCER TISSUE; CELL FUNCTION; CELL MATURATION; CELL MIGRATION; CELL MOTILITY; EPITHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MOUTH CANCER; NEURONAL DEVELOPMENT; ORAL SQUAMOUS CELL CARCINOMA; PRIORITY JOURNAL;

CELL LINE, TUMOR; CELL MOVEMENT; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; MOUTH NEOPLASMS; NEURONS;

EID: 37448999137     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.11.179     Document Type: Article

References (21)

1. Sanchez C., Diaz-Nido J., and Avila J. Phosphorylation of microtubule-associated protein 2 (MAP2) and its relevance for the regulation of the neuronal cytoskeleton function. Prog. Neurobiol. 61 (2000) 133-168
2. Wiche G. High-Mr microtubule-associated proteins: properties and functions. Biochem. J. 259 (1989) 1-12
3. Kalcheva N., Weidenheim K.M., Kress Y., and Shafit-Zagardo B. Expression of microtubule-associated protein-2a and other novel microtubule-associated protein-2 transcripts in human fetal spinal cord. J. Neurochem. 68 (1997) 383-391
4. Albala J.S., Kress Y., Liu W.K., Weidenheim K., Yen S.H., and Shafit-Zagardo B. Human microtubule-associated protein-2c localizes to dendrites and axons in fetal spinal motor neurons. J. Neurochem. 64 (1995) 2480-2490
5. Johnson G.V., and Jope R.S. The role of microtubule-associated protein 2 (MAP-2) in neuronal growth, plasticity, and degeneration. J. Neurosci. Res. 33 (1992) 505-512
6. Sheetz M.P., Pfister K.K., Bulinski J.C., and Cotman C.W. Mechanisms of trafficking in axons and dendrites: implications for development and neurodegeneration. Prog. Neurobiol. 55 (1998) 577-594
7. Sharma N., Kress Y., and Shafit-Zagardo B. Antisense MAP-2 oligonucleotides induce changes in microtubule assembly and neuritic elongation in pre-existing neurites of rat cortical neurons. Cell Motil. Cytoskeleton 27 (1994) 234-247
8. Boucher M., Belanger D., Beaulieu C., and Leclerc N. Tau-mediated process outgrowth is differentially altered by the expression of MAP2b and MAP2c in Sf9 cells. Cell Motil. Cytoskeleton 42 (1999) 257-273
9. Sanchez C., Tompa P., Szucs K., Friedrich P., and Avila J. Phosphorylation and dephosphorylation in the proline-rich C-terminal domain of microtubule-associated protein 2. Eur. J. Biochem. 241 (1996) 765-771
10. Itoh T.J., Hisanaga S., Hosoi T., Kishimoto T., and Hotani H. Phosphorylation states of microtubule-associated protein 2 (MAP2) determine the regulatory role of MAP2 in microtubule dynamics. Biochemistry 36 (1997) 12574-12582
11. Bershadsky A.D., Vaisberg E.A., and Vasiliev J.M. Pseudopodial activity at the active edge of migrating fibroblast is decreased after drug-induced microtubule depolymerization. Cell Motil. Cytoskeleton 19 (1991) 152-158
12. Ichii T., and Takeichi M. p120-catenin regulates microtubule dynamics and cell migration in a cadherin-independent manner. Genes Cells 12 (2007) 827-839
13. Kroboth K., Newton I.P., Kita K., Dikovskaya D., Zumbrunn J., Waterman-Storer C.M., and Nathke I.S. Lack of adenomatous polyposis coli protein correlates with a decrease in cell migration and overall changes in microtubule stability. Mol. Biol. Cell 18 (2007) 910-918
14. Lu H., Murtagh J., and Schwartz E.L. The microtubule binding drug laulimalide inhibits vascular endothelial growth factor-induced human endothelial cell migration and is synergistic when combined with docetaxel (taxotere). Mol. Pharmacol. 69 (2006) 1207-1215
15. Hu Y.L., Li S., Miao H., Tsou T.C., del Pozo M.A., and Chien S. Roles of microtubule dynamics and small GTPase Rac in endothelial cell migration and lamellipodium formation under flow. J. Vasc. Res. 39 (2002) 465-476
16. Teng J., Takei Y., Harada A., Nakata T., Chen J., and Hirokawa N. Synergistic effects of MAP2 and MAP1B knockout in neuronal migration, dendritic outgrowth, and microtubule organization. J. Cell Biol. 155 (2001) 65-76
17. Chen J.Y., Chang Y.L., Yu Y.C., Chao C.C., Kao H.W., Wu C.T., Lin W.C., Ko J.Y., and Jou Y.S. Specific induction of the high-molecular-weight microtubule-associated protein 2 (hmw-MAP2) by betel quid extract in cultured oral keratinocytes: clinical implications in betel quid-associated oral squamous cell carcinoma (OSCC). Carcinogenesis 25 (2004) 269-276
18. Kalcheva N., Rockwood J.M., Kress Y., Steiner A., and Shafit-Zagardo B. Molecular and functional characteristics of MAP-2a: ability of MAP-2a versus MAP-2b to induce stable microtubules in COS cells. Cell Motil. Cytoskeleton 40 (1998) 272-285
19. Dehmelt L., and Halpain S. Actin and microtubules in neurite initiation: are MAPs the missing link?. J. Neurobiol. 58 (2004) 18-33
20. Fang D., Hallman J., Sangha N., Kute T.E., Hammarback J.A., White W.L., and Setaluri V. Expression of microtubule-associated protein 2 in benign and malignant melanocytes: implications for differentiation and progression of cutaneous melanoma. Am. J. Pathol. 158 (2001) 2107-2115
21. Liu Y., Sturgis C.D., Grzybicki D.M., Jasnosz K.M., Olson P.R., Tong M., Dabbs D.D., Raab S.S., and Silverman J.F. Microtubule-associated protein-2: a new sensitive and specific marker for pulmonary carcinoid tumor and small cell carcinoma. Mod. Pathol. 14 (2001) 880-885