Synthesis and biological evaluation of a des-dihydropyran laulimalide analog

Tetrahedron Letters

Volumn 50, Issue 42, 2009, Pages 5790-5792

  Gollner, Andreas ^a   Altmann, Karl Heinz ^b   Gertsch, Jürg ^c   Mulzer, Johann ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b ETH ZURICH   (Switzerland)

^c UNIVERSITY OF BERN   (Switzerland)

Author keywords

Antitumor drugs; Evans alkylation; Macrolactonization; SAR studies; Total synthesis

Indexed keywords

LAULIMALIDE; LAULIMALIDE DERIVATIVE; PYRAN DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL STRAIN HCT116; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; LACTONIZATION; OLEFINATION; REACTION ANALYSIS; RING CLOSING METATHESIS; STRUCTURE ACTIVITY RELATION;

EID: 69249233627     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2009.07.122     Document Type: Article

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